G:2068

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Official Symbol ERCC2
Aliases EM9, TTD, XPD, COFS2, MGC102762, MGC126218, MGC126219
EntrezGene 2068
UniProt Coming Soon
Unique Molecular Interactions 9
Total Molecular Interactions 16
Total Single Events 37
Unique Interaction Partners 6

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ERCC2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ERCC2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ERCC2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
2 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
3 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
4 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
5 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
6 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
7 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
8 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
9 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 2068. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 2068. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
2 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
3 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
4 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
5 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
6 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
7 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
8 INT149430 Localization of ERCC2 1 0.43 0.76 0
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