G:20750

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Official Symbol Spp1
Aliases OP, 2AR, Bsp, Eta, Opn, Ric, BNSP, BSPI, Opnl, Apl-1, ETA-1, Spp-1
EntrezGene 20750
UniProt Coming Soon
Unique Molecular Interactions 41
Total Molecular Interactions 50
Total Single Events 479
Unique Interaction Partners 27

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Spp1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Spp1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Spp1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
2 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
3 INT282420 Spp1 Positive_regulation of Ins1 1 0.20 1.25 0.32
4 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3
5 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
6 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28
7 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
8 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
9 INT329311 Spp1 Positive_regulation of IFN1@ 1 0.20 1.2 0.23
10 INT329306 Spp1 Positive_regulation of Il12a 1 0.08 1.19 0.23
11 INT299155 Smcp Negative_regulation of Spp1 1 0.00 0.7 0.22
12 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
13 INT329310 Spp1 Positive_regulation of Gene_expression of IFN1@ 1 0.48 0.88 0.19
14 INT329309 Spp1 Regulation of Gene_expression of IFN1@ 1 0.26 0.82 0.19
15 INT242993 Positive_regulation of Ppara Positive_regulation of Gene_expression of Spp1 1 0.24 0.66 0.18
16 INT329305 Spp1 Positive_regulation of Gene_expression of Il12a 1 0.12 0.88 0.16
17 INT329304 Spp1 Negative_regulation of Gene_expression of Il10 1 0.06 0.93 0.13
18 INT329303 Spp1 Positive_regulation of Localization of Il12a 1 0.12 0.92 0.12
19 INT320768 Spp1 Regulation of Protein_catabolism of Dsg1a 1 0.08 0.77 0.11
20 INT264838 Binding of Eno2 and Spp1 1 0.00 0.17 0.1
21 INT289711 Binding of F2 and Spp1 1 0.08 0.21 0.08
22 INT289710 F2 Regulation of Spp1 1 0.04 0 0.08
23 INT225781 Ppi-rs Positive_regulation of Gene_expression of Spp1 1 0.03 1 0.07
24 INT225791 Ppi-rs Positive_regulation of Spp1 1 0.02 0.49 0.04
25 INT176549 Mtv7 Positive_regulation of Spp1 1 0.26 0.86 0.03
26 INT176540 Pik3cd Positive_regulation of Spp1 1 0.11 1.8 0.03
27 INT176543 Binding of Cd44 and Spp1 2 0.31 0.57 0
28 INT320766 Spp1 Negative_regulation of Dsg1a 1 0.11 1.05 0
29 INT176548 Gopc Regulation of Gene_expression of Spp1 1 0.12 0 0
30 INT176538 Mapk1 Positive_regulation of Gene_expression of Spp1 1 0.12 0.43 0
31 INT176551 Binding of Pik3r1 and Spp1 1 0.03 0.65 0
32 INT344401 Agtr2 Positive_regulation of Gene_expression of Spp1 1 0.01 3.21 0
33 INT176534 Mapk14 Positive_regulation of Spp1 1 0.14 0.42 0
34 INT176554 Ass1 Positive_regulation of Gene_expression of Spp1 1 0.01 1.26 0
35 INT176555 Ass1 Positive_regulation of Spp1 1 0.01 0 0
36 INT344405 Binding of EGFR and Spp1 1 0.09 1.34 0
37 INT176550 Pik3r1 Positive_regulation of Gene_expression of Spp1 1 0.05 0.47 0
38 INT176556 Binding of Mapk14 and Positive_regulation of Gene_expression of Spp1 1 0.14 0.43 0
39 INT176544 Mapk14 Positive_regulation of Transcription of Spp1 1 0.20 0.42 0
40 INT176557 Binding of Pik3r1 and Mtv7 Regulation of Gene_expression of Spp1 1 0.02 0.46 0
41 INT176541 Mapk1 Positive_regulation of Spp1 1 0.13 0.42 0
42 INT176547 Mapk1 Positive_regulation of Transcription of Spp1 1 0.18 0.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 20750. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 20750. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
2 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49
3 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33
4 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33
5 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28
6 INT176510 Binding of Spp1 21 0.42 22.1 2
7 INT176516 Localization of Spp1 28 0.76 19.39 1.9
8 INT242988 Positive_regulation of Transcription of Spp1 4 0.28 3.28 0.92
9 INT176528 Regulation of Spp1 9 0.45 9.05 0.77
10 INT176513 Transcription of Spp1 5 0.63 4.32 0.67
11 INT242987 Positive_regulation of Localization of Spp1 3 0.60 7.04 0.59
12 INT289704 Protein_catabolism of Spp1 5 0.27 2.42 0.39
13 INT176519 Regulation of Gene_expression of Spp1 7 0.58 8.54 0.35
14 INT329301 Phosphorylation of Spp1 1 0.62 1.71 0.34
15 INT176518 Positive_regulation of Positive_regulation of Spp1 5 0.47 3.36 0.28
16 INT248262 Negative_regulation of Positive_regulation of Spp1 1 0.04 0.65 0.24
17 INT176522 Negative_regulation of Localization of Spp1 3 0.37 2.65 0.17
18 INT316578 Regulation of Transcription of Spp1 1 0.09 0.16 0
19 INT316579 Negative_regulation of Binding of Spp1 1 0.09 0.06 0
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