G:21939

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Official Symbol Cd40
Aliases IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936
EntrezGene 21939
UniProt Coming Soon
Unique Molecular Interactions 33
Total Molecular Interactions 72
Total Single Events 389
Unique Interaction Partners 24

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cd40. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cd40. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cd40. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52
3 INT189849 Binding of Cd40 and Churc1 Regulation of Gene_expression of Ik 1 0.00 0.73 0.41
4 INT189846 Binding of Cd40 and Churc1 1 0.01 0.73 0.41
5 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
6 INT188696 Binding of Cd40 and Eae1 1 0.05 1.57 0.21
7 INT238001 Cxcl10 Positive_regulation of Gene_expression of Cd40 1 0.17 0.91 0.21
8 INT311987 Binding of Cd40 and Negative_regulation of Regulation of Hand1 1 0.28 0.27 0.21
9 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18
10 INT310257 Tlr4 Positive_regulation of Gene_expression of Cd40 1 0.13 0.06 0.15
11 INT188697 Il6 Positive_regulation of Cd40 1 0.05 0.18 0.14
12 INT249598 Stat1 Positive_regulation of Gene_expression of Cd40 1 0.41 0.46 0.14
13 INT324128 Binding of Cd4 and Cd40 2 0.29 0.3 0.13
14 INT331564 Binding of Apcs and Cd40 1 0.12 0.74 0.13
15 INT189848 IFN1@ Positive_regulation of Gene_expression of Cd40 1 0.69 0 0.09
16 INT249601 IFNA1 Negative_regulation of Gene_expression of Cd40 1 0.42 0.51 0.09
17 INT252344 Binding of Cd40 and Mthfd1 2 0.16 0.34 0.08
18 INT231504 Binding of Tlr4 and Cd40 1 0.09 0.18 0.08
19 INT220903 Regulation of Binding of Crp and Cd40 1 0.05 0.37 0.05
20 INT220906 Binding of Crp and Cd40 1 0.04 0.37 0.05
21 INT284559 Gopc Positive_regulation of Cd40 1 0.19 0.23 0.05
22 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03
23 INT252339 Binding of Cd40 and Positive_regulation of Mthfd1 1 0.04 0.19 0
24 INT349016 Negative_regulation of Binding of Cd80 and Cd40 1 0.25 0 0
25 INT220901 Regulation of Binding of Saa1 and Cd40 1 0.04 0.36 0
26 INT290160 Atp6v1e1 Positive_regulation of Cd40 1 0.24 0.5 0
27 INT252341 Cd40 Positive_regulation of Gene_expression of Cd80 1 0.12 0.1 0
28 INT248298 Binding of Cd40 and Rf 1 0.08 0 0
29 INT314970 Binding of Cd40 and Lbr 1 0.03 0.07 0
30 INT252334 Positive_regulation of Binding of Cd40 and Cd40lg 1 0.11 0.1 0
31 INT284553 Adc Positive_regulation of Gene_expression of Cd40 1 0.18 0.35 0
32 INT220900 Binding of C4bp and Cd40 1 0.21 0.72 0
33 INT252348 Binding of Cd40 and Cd40lg Positive_regulation of Gene_expression of Cd80 1 0.06 0.15 0
34 INT220908 Binding of Saa1 and Cd40 1 0.04 0.36 0
35 INT349017 Binding of Cd80 and Cd40 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 21939. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 21939. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
2 INT133156 Binding of Cd40 77 0.48 45.92 13.77
3 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51
4 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56
5 INT142606 Regulation of Gene_expression of Cd40 13 0.56 6.15 3.27
6 INT96151 Negative_regulation of Gene_expression of Cd40 20 0.58 6.06 2.58
7 INT248297 Negative_regulation of Cd40 14 0.58 8.96 2.34
8 INT188691 Negative_regulation of Binding of Cd40 3 0.42 2.49 1.31
9 INT189836 Regulation of Cd40 10 0.40 3.02 1.1
10 INT5211 Localization of Cd40 6 0.78 1.75 0.71
11 INT269970 Positive_regulation of Positive_regulation of Cd40 2 0.50 1.79 0.57
12 INT188663 Regulation of Binding of Cd40 1 0.41 0.95 0.55
13 INT188680 Positive_regulation of Binding of Cd40 1 0.46 1.33 0.32
14 INT176333 Transcription of Cd40 1 0.52 0.8 0.28
15 INT5213 Regulation of Localization of Cd40 1 0.26 0 0.27
16 INT311985 Regulation of Positive_regulation of Cd40 1 0.45 0.64 0.24
17 INT252316 Regulation of Regulation of Cd40 2 0.24 0.71 0.15
18 INT311981 Regulation of Protein_catabolism of Cd40 1 0.45 0.31 0.07
19 INT311983 Protein_catabolism of Cd40 1 0.88 0.31 0.07
20 INT284542 Negative_regulation of Positive_regulation of Cd40 1 0.27 0.28 0
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