G:21943

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Official Symbol Tnfsf11
Aliases ODF, OPG, OPGL, RANKL, Ly109l, Trance
EntrezGene 21943
UniProt Coming Soon
Unique Molecular Interactions 43
Total Molecular Interactions 74
Total Single Events 453
Unique Interaction Partners 30

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Tnfsf11. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Tnfsf11. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Tnfsf11. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
2 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
3 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
4 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71
5 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7
6 INT187220 Il11 Positive_regulation of Gene_expression of Tnfsf11 1 0.13 0.86 0.69
7 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
8 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
9 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
10 INT187227 Vip Negative_regulation of Gene_expression of Tnfsf11 1 0.35 1.23 0.51
11 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
12 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49
13 INT165764 Tnfsf11 Positive_regulation of Mapk3 1 0.17 1.08 0.33
14 INT165766 Tnfsf11 Negative_regulation of Tnfsf11 Positive_regulation of Nfkb1 1 0.00 1.08 0.33
15 INT165765 Tnfsf11 Positive_regulation of Nfkb1 1 0.01 1.07 0.33
16 INT165763 Tnfsf11 Positive_regulation of Phosphorylation of Mapk3 1 0.40 1.08 0.33
17 INT187223 Il1 Positive_regulation of Gene_expression of Tnfsf11 1 0.09 0.64 0.32
18 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31
19 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31
20 INT301279 Tnfsf11 Regulation of Gene_expression of Mmp9 1 0.13 0.34 0.21
21 INT171973 Tnfsf11 Positive_regulation of Gene_expression of Il1 1 0.06 0.21 0.21
22 INT171972 Tnfsf11 Positive_regulation of Gene_expression of Il6 1 0.08 0.21 0.21
23 INT301281 Tnfsf11 Regulation of Gene_expression of Clec5a 1 0.22 0.34 0.21
24 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21
25 INT301290 Tnfsf11 Positive_regulation of Nfatc1 1 0.15 0.65 0.2
26 INT301282 Tnfsf11 Positive_regulation of Traf6 1 0.10 0.65 0.2
27 INT355364 Regulation of PTHLH Positive_regulation of Tnfsf11 1 0.04 1.51 0.19
28 INT355363 PTHLH Positive_regulation of Tnfsf11 1 0.04 1.47 0.19
29 INT355365 CSF1 Positive_regulation of Tnfsf11 1 0.03 1.49 0.19
30 INT355366 Regulation of CSF1 Positive_regulation of Tnfsf11 1 0.02 1.5 0.19
31 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17
32 INT148532 Binding of CCL3 and Tnfsf11 1 0.03 0.71 0.14
33 INT301284 Tnfsf11 Positive_regulation of Localization of Nfatc1 1 0.16 0.32 0.11
34 INT93535 PTH Negative_regulation of Gene_expression of Tnfsf11 1 0.19 0.22 0.11
35 INT107909 Binding of Tnfsf11 and Tnfrsf22 1 0.01 2.12 0.11
36 INT254284 Binding of TNF and Tnfsf11 1 0.04 0.44 0.1
37 INT338999 Binding of BTF3P11 and Tnfsf11 1 0.01 0.35 0.08
38 INT254277 Binding of Hand1 and Tnfsf11 1 0.02 0.08 0.08
39 INT314369 Tnfsf11 Negative_regulation of Gene_expression of Tnfrsf11b 1 0.08 2.2 0.05
40 INT232206 Binding of Tgfb1 and Tnfsf11 1 0.02 0.52 0.04
41 INT217474 Tnfrsf11a Regulation of Gene_expression of Tnfsf11 1 0.41 1.2 0.04
42 INT210581 Binding of AMELX and Tnfsf11 1 0.01 0.15 0
43 INT217480 Tnfsf11 Negative_regulation of Tnfrsf11a 1 0.39 0.75 0
44 INT210580 Negative_regulation of Binding of TNFRSF11A and Tnfsf11 1 0.07 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 21943. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 21943. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
2 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
3 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45
4 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35
5 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23
6 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84
7 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78
8 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39
9 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39
10 INT105551 Transcription of Tnfsf11 6 0.69 4.21 1.38
11 INT105552 Positive_regulation of Transcription of Tnfsf11 3 0.31 2.94 1.17
12 INT210586 Negative_regulation of Positive_regulation of Tnfsf11 3 0.41 1.4 1.02
13 INT132847 Negative_regulation of Localization of Tnfsf11 1 0.32 0.16 1.01
14 INT171963 Positive_regulation of Positive_regulation of Tnfsf11 3 0.42 2.44 0.93
15 INT165760 Positive_regulation of Binding of Tnfsf11 2 0.36 1.83 0.71
16 INT264991 Positive_regulation of Localization of Tnfsf11 5 0.24 3.22 0.59
17 INT207379 Regulation of Negative_regulation of Tnfsf11 2 0.28 1.7 0.5
18 INT165761 Phosphorylation of Tnfsf11 3 0.75 2.76 0.4
19 INT187214 Negative_regulation of Binding of Tnfsf11 1 0.25 1.01 0.38
20 INT210588 Protein_catabolism of Tnfsf11 1 0.72 1.43 0.23
21 INT144491 Negative_regulation of Transcription of Tnfsf11 1 0.42 0.82 0.07
22 INT232197 Positive_regulation of Phosphorylation of Tnfsf11 1 0.46 0.6 0.04
23 INT232196 Negative_regulation of Negative_regulation of Tnfsf11 1 0.39 1.5 0.04
24 INT210591 Positive_regulation of Negative_regulation of Tnfsf11 1 0.47 1.46 0.03
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