G:22059

From wiki-pain
Jump to: navigation, search
Official Symbol Trp53
Aliases bbl, bfy, bhy, p44, p53, Tp53
EntrezGene 22059
UniProt Coming Soon
Unique Molecular Interactions 71
Total Molecular Interactions 82
Total Single Events 658
Unique Interaction Partners 49

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Trp53. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Trp53. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Trp53. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
2 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
3 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
4 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
5 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
6 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
7 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
8 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
9 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
10 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
11 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
12 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
13 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
14 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
15 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
16 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
17 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
18 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
19 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
20 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
21 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
22 INT345197 Gpr87 Regulation of Gpr87 Regulation of Trp53 1 0.00 0.42 0.05
23 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
24 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
25 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
26 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
27 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
28 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
29 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
30 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
31 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
32 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
33 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
34 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
35 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
36 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
37 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
38 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
39 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0
40 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0
41 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
42 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
43 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
44 INT342007 Mta1 Regulation of Trp53 1 0.15 0.15 0
45 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
46 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
47 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
48 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
49 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
50 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
51 INT225564 Ncoa6 Regulation of Trp53 1 0.04 0.93 0
52 INT352617 Mdm2 Positive_regulation of Positive_regulation of Trp53 1 0.20 2.56 0
53 INT276380 Binding of PIM1 and Trp53 1 0.01 0.66 0
54 INT305540 Binding of Trp53 and Tpt1 1 0.07 0.9 0
55 INT333697 Binding of Hr and Trp53 1 0.19 0.56 0
56 INT179090 Positive_regulation of Myc Regulation of Gene_expression of Trp53 1 0.23 0.69 0
57 INT301466 Smyd2 Negative_regulation of Binding of Trp53 1 0.20 0.3 0
58 INT301468 Smyd2 Negative_regulation of Trp53 1 0.20 0.31 0
59 INT193120 Trp53 Regulation of Trp53 Regulation of Birc5 1 0.08 0.55 0
60 INT333695 Trp53 Positive_regulation of Localization of Bcl2l1 1 0.23 1.33 0
61 INT333693 Hr Negative_regulation of Gene_expression of Trp53 1 0.27 0.9 0
62 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
63 INT333691 Trp53 Positive_regulation of Bcl2l1 1 0.23 1.33 0
64 INT305541 Binding of Bcl2 and Trp53 1 0.05 0.9 0
65 INT305539 Binding of Mki67 and Trp53 1 0.20 0.91 0
66 INT352614 Negative_regulation of Binding of Mdm2 and Trp53 1 0.19 1.16 0
67 INT342251 Binding of Trp53 and Tymp 1 0.21 1.01 0
68 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0
69 INT333687 Trp53 Positive_regulation of Localization of Bcl2 1 0.45 1.24 0
70 INT301465 Mdm4 Negative_regulation of Trp53 1 0.13 0.35 0
71 INT333686 Gene_expression of Hr Negative_regulation of Gene_expression of Trp53 1 0.23 1.02 0
72 INT253022 PTTG1 Negative_regulation of Negative_regulation of Trp53 1 0.03 1.34 0
73 INT193119 Trp53 Regulation of Birc5 1 0.19 0.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 22059. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 22059. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
2 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
3 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
4 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
5 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
6 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
7 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
8 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
9 INT172953 Binding of Trp53 33 0.37 20.76 1.41
10 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
11 INT174156 Localization of Trp53 16 0.72 13.52 1.18
12 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
13 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
14 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
15 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
16 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
17 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
18 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
19 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
20 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
21 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
22 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
23 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
24 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
25 INT333669 Positive_regulation of Transcription of Trp53 3 0.45 2.33 0
26 INT333668 Regulation of Protein_catabolism of Trp53 1 0.24 1.58 0
27 INT333671 Regulation of Transcription of Trp53 1 0.24 0.83 0
28 INT179076 Negative_regulation of Protein_catabolism of Trp53 1 0.32 0.43 0
29 INT333663 Positive_regulation of Protein_catabolism of Trp53 1 0.45 0.84 0
30 INT333662 Negative_regulation of Transcription of Trp53 1 0.53 1.15 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox