G:2247

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Official Symbol FGF2
Aliases BFGF, FGFB, FGF-2, HBGF-2
EntrezGene 2247
UniProt Coming Soon
Unique Molecular Interactions 41
Total Molecular Interactions 48
Total Single Events 311
Unique Interaction Partners 28

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to FGF2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to FGF2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to FGF2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84
2 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
3 INT56091 FGF2 Positive_regulation of Transcription of SERPINE1 1 0.43 0.41 0.28
4 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22
5 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
6 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18
7 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18
8 INT24667 Binding of COL7A1 and FGF2 1 0.13 0.25 0.16
9 INT274472 IL12A Negative_regulation of Gene_expression of FGF2 1 0.02 0.36 0.14
10 INT274473 IL12A Regulation of Gene_expression of FGF2 1 0.02 0.36 0.14
11 INT170991 FGF2 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.72 0.13
12 INT351545 FGF2 Positive_regulation of CDH16 1 0.01 0.19 0.1
13 INT351546 FGF2 Positive_regulation of L1CAM 1 0.34 0.19 0.1
14 INT351543 FGF2 Positive_regulation of NCAM1 1 0.03 0.14 0.1
15 INT122546 FGF2 Regulation of Localization of IL6 1 0.55 0.1 0.1
16 INT122542 FGF2 Positive_regulation of Localization of IL6 1 0.62 0.09 0.09
17 INT117838 FGFR1 Regulation of FGF2 1 0.33 0.17 0.09
18 INT301921 UCK2 Regulation of Gene_expression of FGF2 1 0.01 1.22 0.08
19 INT24666 Binding of EGF and FGF2 1 0.35 0 0.06
20 INT295715 PTGER2 Regulation of Localization of FGF2 1 0.02 0.6 0.05
21 INT295723 VEGFA Regulation of Localization of FGF2 1 0.07 0.6 0.05
22 INT351155 AKT1 Positive_regulation of Positive_regulation of FGF2 1 0.03 0.81 0
23 INT260268 Binding of FGF2 and FGFR1 1 0.46 0.94 0
24 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0
25 INT183090 Gene_expression of SULF1 Positive_regulation of Phosphorylation of FGF2 1 0.19 0.42 0
26 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
27 INT183093 SULF1 Negative_regulation of Binding of FGF2 1 0.17 0.41 0
28 INT180856 FGF2 Positive_regulation of Transcription of MT1L 1 0.30 1.06 0
29 INT122541 FGF2 Positive_regulation of Transcription of IL6 1 0.42 0 0
30 INT122544 FGF2 Positive_regulation of Positive_regulation of GRAP2 1 0.20 0 0
31 INT249454 us Positive_regulation of Gene_expression of FGF2 1 0.01 0.13 0
32 INT342559 FGF2 Positive_regulation of MAPK1 1 0.08 1.22 0
33 INT122539 FGF2 Regulation of Transcription of IL6 1 0.24 0 0
34 INT260266 Binding of FGF2 and FGFBP1 1 0.48 0.94 0
35 INT122537 FGF2 Positive_regulation of Gene_expression of IL6 1 0.45 0 0
36 INT122536 FGF2 Positive_regulation of Positive_regulation of SGSM3 1 0.73 0 0
37 INT122540 FGF2 Positive_regulation of Binding of JUN 1 0.24 0 0
38 INT122543 FGF2 Positive_regulation of JUN 1 0.36 0 0
39 INT122545 FGF2 Positive_regulation of Positive_regulation of MAPK3 1 0.53 0 0
40 INT342557 FGF2 Positive_regulation of MAPK3 1 0.03 1.21 0
41 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 2247. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 2247. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
2 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17
3 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24
4 INT115317 Transcription of FGF2 14 0.62 12.79 3
5 INT174864 Positive_regulation of Transcription of FGF2 8 0.44 7.58 3
6 INT88810 Positive_regulation of Gene_expression of FGF2 17 0.50 12.62 2.98
7 INT24672 Localization of FGF2 27 0.71 14.59 2.48
8 INT97898 Regulation of FGF2 8 0.60 3.85 2.09
9 INT122547 Positive_regulation of Positive_regulation of FGF2 3 0.44 3.1 1.49
10 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48
11 INT24671 Binding of FGF2 14 0.35 8.73 1.43
12 INT174866 Regulation of Gene_expression of FGF2 4 0.39 7.13 1.2
13 INT147407 Protein_catabolism of FGF2 1 0.91 0.33 1.06
14 INT174870 Negative_regulation of Transcription of FGF2 1 0.37 1.66 0.38
15 INT122548 Negative_regulation of Localization of FGF2 3 0.41 1.01 0.22
16 INT174869 Regulation of Negative_regulation of FGF2 1 0.39 1.59 0.22
17 INT175919 Negative_regulation of Positive_regulation of FGF2 1 0.22 0.96 0.22
18 INT331725 Regulation of Localization of FGF2 2 0.17 0.52 0.19
19 INT326978 Regulation of Binding of FGF2 1 0.21 0.06 0.13
20 INT174865 Regulation of Transcription of FGF2 1 0.39 0.72 0.11
21 INT183123 Phosphorylation of FGF2 3 0.30 1.2 0.08
22 INT301929 Positive_regulation of Localization of FGF2 1 0.23 1.05 0.04
23 INT144612 Positive_regulation of Binding of FGF2 2 0.28 0.93 0
24 INT183130 Positive_regulation of Phosphorylation of FGF2 1 0.18 0.2 0
25 INT183115 Negative_regulation of Phosphorylation of FGF2 1 0.15 0.25 0
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