G:23411

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Official Symbol SIRT1
Aliases SIR2L1
EntrezGene 23411
UniProt Coming Soon
Unique Molecular Interactions 10
Total Molecular Interactions 11
Total Single Events 62
Unique Interaction Partners 5

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to SIRT1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to SIRT1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to SIRT1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT204318 NOS3 Regulation of NOS3 Regulation of SIRT1 1 0.20 0.1 0
2 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
3 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
4 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
5 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
6 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
7 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
8 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
9 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
10 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0
11 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 23411. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 23411. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
2 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
3 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
4 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
5 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
6 INT204349 Regulation of SIRT1 8 0.61 1.99 0
7 INT204353 Transcription of SIRT1 3 0.68 0.67 0
8 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0
9 INT204371 Positive_regulation of Transcription of SIRT1 1 0.49 0.13 0
10 INT318239 Regulation of Transcription of SIRT1 1 0.26 0.45 0
11 INT350520 Phosphorylation of SIRT1 1 0.25 0.72 0
12 INT204356 Regulation of Gene_expression of SIRT1 1 0.61 0.29 0
13 INT204331 Binding of SIRT1 1 0.47 0.39 0
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