G:240

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Official Symbol ALOX5
Aliases 5-LO, 5LPG, LOG5, 5-LOX, MGC163204
EntrezGene 240
UniProt Coming Soon
Unique Molecular Interactions 32
Total Molecular Interactions 51
Total Single Events 391
Unique Interaction Partners 18

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ALOX5. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ALOX5. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ALOX5. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
2 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9
3 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
4 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81
5 INT203164 PTGER2 Regulation of ALOX5 1 0.00 0.9 0.78
6 INT203171 PTGER2 Negative_regulation of ALOX5 1 0.01 0.89 0.77
7 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59
8 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57
9 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
10 INT203163 LTB4R Regulation of Gene_expression of ALOX5 1 0.00 0.98 0.41
11 INT312123 ELANE Positive_regulation of ALOX5 1 0.09 0.74 0.4
12 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
13 INT39208 ALOX5 Regulation of Gene_expression of IL2 1 0.04 0.06 0.34
14 INT312085 ELANE Regulation of Regulation of ALOX5 1 0.09 0.64 0.32
15 INT59189 Negative_regulation of GBE1 Negative_regulation of ALOX5 1 0.00 0.33 0.31
16 INT203170 Negative_regulation of CPOX Positive_regulation of ALOX5 1 0.01 0.53 0.29
17 INT313498 Binding of ALOX5 and SNRNP70 1 0.05 2.7 0.21
18 INT312091 ALOX5AP Regulation of Transcription of ALOX5 1 0.13 0.37 0.18
19 INT313554 Binding of ALOX5 and Cor 1 0.02 2.47 0.17
20 INT312095 LTB4R Positive_regulation of ALOX5 1 0.01 0.32 0.16
21 INT312096 ELANE Positive_regulation of Transcription of ALOX5 1 0.06 0.27 0.13
22 INT312121 Negative_regulation of PTGER2 Regulation of Gene_expression of ALOX5 1 0.02 0.2 0.1
23 INT273354 Binding of ALOX5 and LTC4S 1 0.04 0.19 0.09
24 INT312103 ELANE Regulation of Gene_expression of ALOX5 1 0.06 0.15 0.08
25 INT313509 Binding of ALOX5 and SP1 1 0.07 1.51 0.08
26 INT184889 Binding of ALOX5 and MCRS1 1 0.06 1.34 0.07
27 INT312087 PTGER2 Regulation of Gene_expression of ALOX5 1 0.01 0.13 0.07
28 INT312110 ELANE Positive_regulation of Gene_expression of ALOX5 1 0.09 0.07 0.04
29 INT312104 Binding of ALOX5 and PTGES 1 0.13 0.14 0.04
30 INT312076 PTGER2 Regulation of ELANE Regulation of ALOX5 1 0.01 0.06 0.03
31 INT184887 MCRS1 Positive_regulation of ALOX5 1 0.11 0.64 0
32 INT313507 Binding of ALOX5 and CXADRP1 1 0.01 0 0
33 INT343160 ACSL4 Regulation of Positive_regulation of ALOX5 1 0.02 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 240. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 240. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
2 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29
3 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47
4 INT28165 Positive_regulation of ALOX5 38 0.47 10.8 5.37
5 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65
6 INT10476 Binding of ALOX5 26 0.36 7.69 3.2
7 INT35448 Negative_regulation of Gene_expression of ALOX5 11 0.57 5.28 3.03
8 INT34905 Positive_regulation of Gene_expression of ALOX5 18 0.50 7.46 2.46
9 INT73926 Localization of ALOX5 8 0.44 3.14 1.52
10 INT170987 Transcription of ALOX5 4 0.69 2.71 1.41
11 INT184896 Negative_regulation of Positive_regulation of ALOX5 2 0.42 0.92 0.96
12 INT205494 Negative_regulation of Negative_regulation of ALOX5 2 0.32 1.2 0.54
13 INT44371 Positive_regulation of Positive_regulation of ALOX5 3 0.31 0.7 0.44
14 INT170989 Regulation of Transcription of ALOX5 2 0.26 0.58 0.39
15 INT44274 Negative_regulation of Regulation of ALOX5 2 0.33 0.28 0.31
16 INT59192 Regulation of Positive_regulation of ALOX5 1 0.15 0.29 0.24
17 INT259885 Regulation of Binding of ALOX5 1 0.07 0.51 0.16
18 INT312131 Positive_regulation of Transcription of ALOX5 1 0.16 0.12 0.06
19 INT184891 Positive_regulation of Localization of ALOX5 2 0.16 0.72 0.03
20 INT312136 Regulation of Regulation of ALOX5 1 0.14 0.06 0.03
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