G:24185

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Official Symbol Akt1
Aliases Akt
EntrezGene 24185
UniProt Coming Soon
Unique Molecular Interactions 90
Total Molecular Interactions 144
Total Single Events 1042
Unique Interaction Partners 58

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Akt1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Akt1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Akt1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
4 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
5 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
6 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
7 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
8 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
9 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
10 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
11 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
12 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
13 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
14 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
15 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
16 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
17 INT309167 Akt1 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.01 0.37 0.48
18 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
19 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
20 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
21 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
22 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
23 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
24 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
25 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
26 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
27 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
28 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
29 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
30 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
31 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
32 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
33 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
34 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
35 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
36 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
37 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
38 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
39 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
40 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
41 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
42 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
43 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16
44 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
45 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15
46 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
47 INT355226 VEGFA Positive_regulation of Akt1 1 0.04 0.27 0.14
48 INT303085 Akt1 Regulation of Gene_expression of Mafk 1 0.12 0.33 0.11
49 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
50 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09
51 INT349031 Epo Positive_regulation of Akt1 1 0.36 0.23 0.09
52 INT303080 Akt1 Negative_regulation of Mafk 1 0.20 0 0.07
53 INT303061 Akt1 Negative_regulation of Syn1 1 0.06 0 0.07
54 INT303055 Akt1 Negative_regulation of Syt1 1 0.21 0 0.07
55 INT300309 Akt1 Regulation of Rorb 1 0.05 3.28 0.06
56 INT300310 Akt1 Regulation of Foxo3 1 0.21 1.5 0.06
57 INT352942 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.33 0.21 0.06
58 INT253362 Il6 Positive_regulation of Akt1 1 0.21 0.07 0.05
59 INT313890 Akt1 Positive_regulation of Gene_expression of XRCC1 1 0.00 0.79 0.05
60 INT303060 Akt1 Regulation of Gene_expression of Syn1 1 0.04 0 0.05
61 INT303064 Negative_regulation of Akt1 Positive_regulation of Gene_expression of Syn1 1 0.07 0.25 0.04
62 INT331153 Akt1 Positive_regulation of Bad 1 0.03 0.92 0.04
63 INT331155 Akt1 Positive_regulation of Binding of Bad 1 0.04 0.93 0.04
64 INT352944 Sh2d6 Negative_regulation of Phosphorylation of Akt1 1 0.06 0.08 0.04
65 INT276211 Pdpk1 Regulation of Akt1 1 0.07 0.72 0.04
66 INT331156 Akt1 Positive_regulation of Phosphorylation of Bad 1 0.02 0.91 0.04
67 INT149751 Rapgef3 Regulation of Phosphorylation of Akt1 1 0.50 0.39 0.04
68 INT321297 Positive_regulation of Binding of Akt1 and Pdk1 1 0.15 0.13 0.03
69 INT239466 Ppp2r1a Regulation of Phosphorylation of Akt1 1 0.01 0 0.03
70 INT321291 Binding of Akt1 and Pdk1 1 0.11 0.13 0.03
71 INT303088 Akt1 Negative_regulation of Gene_expression of CANX 1 0.10 0.28 0
72 INT303089 Akt1 Negative_regulation of CANX 1 0.10 0.28 0
73 INT246801 Negative_regulation of Akt1 Negative_regulation of Phosphorylation of Tsc2 1 0.17 0 0
74 INT246792 Akt1 Positive_regulation of Phosphorylation of Tsc2 1 0.19 0.78 0
75 INT246798 Akt1 Regulation of Tsc2 1 0.16 0.34 0
76 INT194003 MAPK1 Regulation of Positive_regulation of Akt1 1 0.01 0 0
77 INT303090 Akt1 Negative_regulation of CADM1 1 0.14 0.29 0
78 INT246805 Ros1 Positive_regulation of Akt1 1 0.05 0 0
79 INT246810 Negative_regulation of Akt1 Positive_regulation of Ogg1 1 0.42 0 0
80 INT256075 Serpina3k Negative_regulation of Phosphorylation of Akt1 1 0.14 0.17 0
81 INT310241 INS Positive_regulation of Akt1 1 0.30 0.98 0
82 INT246802 Pik3c3 Positive_regulation of Positive_regulation of Akt1 1 0.04 0 0
83 INT246782 Ros1 Positive_regulation of Positive_regulation of Akt1 1 0.06 0.66 0
84 INT246806 Gene_expression of Akt1 Positive_regulation of Phosphorylation of Tsc2 1 0.19 0.32 0
85 INT246803 Binding of Akt1 and Tsc2 1 0.14 0.85 0
86 INT281610 Positive_regulation of Akt1 Positive_regulation of Gsk3b 1 0.02 0.12 0
87 INT276212 Binding of Akt1 and Gsk3a 1 0.11 0 0
88 INT303087 Akt1 Negative_regulation of Gene_expression of CADM1 1 0.14 0.29 0
89 INT246785 Tgfb1i1 Positive_regulation of Positive_regulation of Akt1 1 0.01 0.66 0
90 INT253371 Akt1 Regulation of Mtor 1 0.05 0.19 0
91 INT186989 Binding of Akt1 and Tert 1 0.00 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24185. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24185. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
2 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
3 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
4 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
5 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
6 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
7 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
8 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
9 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
10 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
11 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
12 INT136692 Localization of Akt1 12 0.78 2.14 3.65
13 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
14 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
15 INT214355 Binding of Akt1 13 0.36 3.72 2.59
16 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
17 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
18 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
19 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
20 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
21 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2
22 INT276192 Transcription of Akt1 1 0.66 0.47 0.18
23 INT214360 Negative_regulation of Binding of Akt1 2 0.41 0.09 0.12
24 INT355216 Positive_regulation of Binding of Akt1 1 0.37 0.35 0.12
25 INT307475 Positive_regulation of Negative_regulation of Akt1 1 0.12 0.12 0.07
26 INT230480 Positive_regulation of Protein_catabolism of Akt1 1 0.06 0.75 0
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