G:242202

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Official Symbol Pde5a
Aliases Cn5n, Pde5, Cgbpde, Pde5a1
EntrezGene 242202
UniProt Coming Soon
Unique Molecular Interactions 14
Total Molecular Interactions 17
Total Single Events 146
Unique Interaction Partners 8

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Pde5a. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Pde5a. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Pde5a. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86
2 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75
3 INT257229 Binding of PRKG1 and Pde5a 1 0.01 0.17 0.41
4 INT221259 Pde5a Positive_regulation of Localization of PRKG1 1 0.00 0.06 0.37
5 INT275094 Pde5a Regulation of Ltp 1 0.05 0 0.35
6 INT257224 Pde5a Positive_regulation of Phosphorylation of Creb1 1 0.03 0.09 0.2
7 INT202297 Pde5a Positive_regulation of Prkg1 1 0.00 0.13 0.18
8 INT257217 Binding of Pde2a and Pde5a 1 0.03 0 0.1
9 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
10 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
11 INT275090 Twist1 Positive_regulation of Gene_expression of Pde5a 1 0.02 0.62 0.04
12 INT275095 Twist1 Positive_regulation of Pde5a 1 0.03 0.62 0.04
13 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
14 INT275091 Negative_regulation of Twist1 Positive_regulation of Pde5a 1 0.02 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 242202. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 242202. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209 Positive_regulation of Pde5a 30 0.21 2.54 16.31
2 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14
3 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27
4 INT73127 Gene_expression of Pde5a 18 0.76 5.25 3.31
5 INT108422 Binding of Pde5a 11 0.36 3.07 2.07
6 INT73126 Positive_regulation of Gene_expression of Pde5a 3 0.59 0.55 1.31
7 INT257200 Phosphorylation of Pde5a 1 0.25 0 0.94
8 INT177532 Localization of Pde5a 2 0.56 0.96 0.81
9 INT257202 Protein_catabolism of Pde5a 2 0.38 0.36 0.66
10 INT208 Negative_regulation of Positive_regulation of Pde5a 3 0.17 2.02 0.65
11 INT275071 Negative_regulation of Protein_catabolism of Pde5a 1 0.17 0.36 0.6
12 INT257211 Negative_regulation of Localization of Pde5a 1 0.13 0.2 0.48
13 INT275073 Positive_regulation of Negative_regulation of Pde5a 1 0.22 0.45 0.3
14 INT42375 Positive_regulation of Positive_regulation of Pde5a 2 0.14 0.1 0.19
15 INT42376 Regulation of Positive_regulation of Pde5a 1 0.03 0 0.18
16 INT177528 Negative_regulation of Binding of Pde5a 1 0.34 0.46 0.15
17 INT275069 Negative_regulation of Gene_expression of Pde5a 1 0.26 0.54 0.13
18 INT257205 Transcription of Pde5a 1 0.21 0 0.08
19 INT323262 Negative_regulation of Negative_regulation of Pde5a 1 0.03 1.32 0.04
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