G:24323

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Official Symbol Edn1
Aliases Et1
EntrezGene 24323
UniProt Coming Soon
Unique Molecular Interactions 67
Total Molecular Interactions 91
Total Single Events 712
Unique Interaction Partners 50

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Edn1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Edn1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Edn1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
2 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
3 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
4 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
5 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
6 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
7 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
8 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
9 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
10 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
11 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
12 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
13 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
14 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
15 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
16 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
17 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
18 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
19 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
20 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
21 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
22 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
23 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
24 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
25 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
26 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
27 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
28 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
29 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
30 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
31 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
32 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
33 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
34 INT6674 Edn1 Positive_regulation of Gene_expression of FOS 1 0.08 0.19 0.1
35 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
36 INT10904 Edn1 Regulation of Localization of Nppb 1 0.22 0.54 0.1
37 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
38 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09
39 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
40 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
41 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08
42 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
43 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07
44 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
45 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05
46 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
47 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
48 INT353314 Edn1 Positive_regulation of Kalrn 1 0.03 0.21 0.04
49 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
50 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
51 INT353317 Edn1 Positive_regulation of RHOA 1 0.19 0.16 0.04
52 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03
53 INT10901 Edn1 Positive_regulation of Localization of Nppb 1 0.39 0.68 0
54 INT6676 Binding of Edn1 and Regulation of Gene_expression of CREB1 1 0.04 0.15 0
55 INT10909 Edn1 Positive_regulation of Nppb 1 0.39 0.16 0
56 INT186689 Binding of ACHE and Edn1 1 0.28 0 0
57 INT186685 Edn1 Regulation of Gene_expression of Il6 1 0.11 1.1 0
58 INT10902 Edn1 Regulation of Avp 1 0.27 0.35 0
59 INT111394 Binding of Edn1 and Pscs 1 0.25 0 0
60 INT191220 Cotl1 Positive_regulation of Edn1 1 0.19 0.69 0
61 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0
62 INT280620 Fig4 Regulation of Gene_expression of Edn1 1 0.03 0 0
63 INT356497 CGA Regulation of Edn1 1 0.02 0 0
64 INT6662 Edn1 Positive_regulation of Positive_regulation of Fos 1 0.00 0.17 0
65 INT10905 Edn1 Regulation of Agt 1 0.11 0.35 0
66 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0
67 INT6675 Edn1 Positive_regulation of Negative_regulation of PENK 1 0.07 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24323. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24323. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
3 INT5048 Binding of Edn1 55 0.47 18.86 19.16
4 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
5 INT6365 Localization of Edn1 56 0.81 18.84 13.83
6 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
7 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
8 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
9 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
10 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
11 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
12 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
13 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
14 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
15 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
16 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
17 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
18 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
19 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
20 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
21 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
22 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
23 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
24 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
25 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
26 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
27 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
28 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
29 INT181578 Negative_regulation of Phosphorylation of Edn1 1 0.37 0.1 0
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