G:24408

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Official Symbol Grin1
Aliases NR1, NMDAR1
EntrezGene 24408
UniProt Coming Soon
Unique Molecular Interactions 48
Total Molecular Interactions 71
Total Single Events 1332
Unique Interaction Partners 36

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Grin1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Grin1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Grin1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
2 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
3 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
4 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
5 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
6 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
7 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
8 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
9 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
10 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
11 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
12 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
13 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
14 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
15 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
16 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
17 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
18 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
19 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
20 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
21 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
22 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
23 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
24 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
25 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
26 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
27 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
28 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
29 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
30 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
31 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
32 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
33 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
34 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
35 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
36 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
37 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
38 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
39 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
40 INT131180 Binding of Grin1 and Oprd1 1 0.24 0 0.39
41 INT121757 Grin1 Regulation of Gene_expression of Fos 1 0.44 0.44 0.35
42 INT13374 Binding of Grin1 and Ltp 1 0.20 0 0.35
43 INT121758 Grin1 Regulation of Positive_regulation of Fos 1 0.44 0.44 0.35
44 INT16382 Binding of Grin1 and Gnmt 1 0.04 0.17 0.32
45 INT238087 Binding of Grin1 and Mmp3 1 0.13 0 0.15
46 INT260495 VEGFA Positive_regulation of Grin1 1 0.08 1.08 0.12
47 INT169858 Grin1 Regulation of Gene_expression of Grin2b 1 0.42 0 0
48 INT169856 Grin1 Positive_regulation of Grin2b 1 0.46 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24408. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24408. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
5 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
6 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
7 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
8 INT11246 Binding of Grin1 65 0.48 14.53 36.93
9 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
10 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
11 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
12 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
13 INT16624 Localization of Grin1 38 0.79 8.46 17.15
14 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
15 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
16 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
17 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
18 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
19 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
20 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
21 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
22 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89
23 INT111405 Negative_regulation of Regulation of Grin1 1 0.54 0.09 1.81
24 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71
25 INT74592 Regulation of Transcription of Grin1 2 0.60 1.05 1.51
26 INT115355 Regulation of Negative_regulation of Grin1 2 0.23 0.23 1.44
27 INT96330 Regulation of Regulation of Grin1 2 0.14 0.83 1.2
28 INT105326 Regulation of Localization of Grin1 3 0.44 0.76 1.16
29 INT235994 Protein_catabolism of Grin1 2 0.42 0.64 0.63
30 INT238082 Positive_regulation of Localization of Grin1 2 0.37 0.23 0.61
31 INT271631 Negative_regulation of Localization of Grin1 2 0.32 0.58 0.52
32 INT53816 Negative_regulation of Binding of Grin1 2 0.39 0 0.3
33 INT238075 Regulation of Protein_catabolism of Grin1 1 0.13 0 0.16
34 INT238070 Positive_regulation of Protein_catabolism of Grin1 1 0.24 0 0.16
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