G:24494

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Official Symbol Il1b
Aliases none
EntrezGene 24494
UniProt Coming Soon
Unique Molecular Interactions 92
Total Molecular Interactions 130
Total Single Events 716
Unique Interaction Partners 43

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il1b. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il1b. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il1b. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
2 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
3 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
4 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
5 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
6 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
7 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
8 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
9 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
10 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
11 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
12 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
13 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
14 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
15 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
16 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
17 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
18 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
19 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
20 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
21 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
22 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
23 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
24 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
25 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
26 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
27 INT10275 Il1b Positive_regulation of Gene_expression of Penk 1 0.49 0.75 0.83
28 INT150993 Sfpq Positive_regulation of Gene_expression of Il1b 1 0.04 0.7 0.72
29 INT83838 Binding of CEACAM6 and Il1b 1 0.05 0 0.71
30 INT150994 Sfpq Negative_regulation of Gene_expression of Il1b 1 0.03 0.69 0.66
31 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
32 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
33 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
34 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
35 INT103214 Binding of Il1b and Pnoc 1 0.40 0.23 0.61
36 INT128814 Ephb1 Negative_regulation of Gene_expression of Il1b 1 0.02 0.37 0.61
37 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6
38 INT105848 Il1b Positive_regulation of Gene_expression of Cpox 1 0.12 0.41 0.59
39 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
40 INT96240 Il13 Negative_regulation of Il1b 1 0.17 0.6 0.59
41 INT96242 Il13 Negative_regulation of Gene_expression of Il1b 1 0.15 0.67 0.59
42 INT128603 Il1b Positive_regulation of Gene_expression of Fos 1 0.50 0.59 0.58
43 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57
44 INT60665 Il1b Regulation of Oprd1 1 0.05 0 0.57
45 INT58805 Il1b Negative_regulation of LH 1 0.24 0 0.56
46 INT134488 Il1b Regulation of Oxt 1 0.30 0.08 0.54
47 INT59601 Il1b Regulation of Localization of LH 1 0.18 0 0.54
48 INT66769 Negative_regulation of Il1b Positive_regulation of Pla2g10 1 0.04 0.25 0.53
49 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51
50 INT58804 Il1b Negative_regulation of Negative_regulation of LH 1 0.24 0 0.51
51 INT143939 Il1b Regulation of Gene_expression of Fos 1 0.10 0.44 0.49
52 INT10277 Il1b Positive_regulation of Transcription of Penk 1 0.46 0.26 0.49
53 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
54 INT114593 Il1b Positive_regulation of Gene_expression of Ppt1 1 0.05 0.06 0.48
55 INT85736 Positive_regulation of Il1b Positive_regulation of Tpgs2 1 0.02 0.2 0.48
56 INT114595 Il1b Positive_regulation of Gene_expression of Rent1 1 0.00 0.06 0.48
57 INT62164 Il1b Positive_regulation of PTGS2 1 0.00 0.49 0.47
58 INT62163 Il1b Positive_regulation of Positive_regulation of PTGS2 1 0.00 0.49 0.47
59 INT85735 Il1b Positive_regulation of Tpgs2 1 0.02 0.2 0.47
60 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
61 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44
62 INT114601 Il1b Positive_regulation of Transcription of Ppt1 1 0.35 0.1 0.41
63 INT83913 Il1b Positive_regulation of Gene_expression of IL6 1 0.01 0.5 0.41
64 INT83915 Il1b Positive_regulation of SERPINA3 1 0.02 0.5 0.41
65 INT83916 Il1b Positive_regulation of IL6 1 0.02 0.5 0.41
66 INT114600 Positive_regulation of Il1b Positive_regulation of Il1rap 1 0.19 0.09 0.4
67 INT114598 Positive_regulation of Il1b Positive_regulation of Trib3 1 0.08 0.08 0.4
68 INT114592 Il1b Positive_regulation of Il1rap 1 0.27 0.09 0.4
69 INT114594 Il1b Positive_regulation of Positive_regulation of Trib3 1 0.08 0.08 0.4
70 INT114596 Il1b Positive_regulation of Trib3 1 0.08 0.08 0.4
71 INT88069 Il1b Positive_regulation of Transcription of Fos 1 0.04 0 0.36
72 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36
73 INT112619 Mapk9 Regulation of Il1b 1 0.16 1.11 0.36
74 INT78063 Il1a Positive_regulation of Il1b 1 0.02 0.07 0.32
75 INT66908 Il1b Positive_regulation of Localization of Avp 1 0.36 0.49 0.31
76 INT128934 Il1b Positive_regulation of Transcription of Ptger4 1 0.00 0 0.29
77 INT128933 Il1b Positive_regulation of Gene_expression of Ptger4 1 0.00 0 0.29
78 INT128932 Il1b Positive_regulation of Gene_expression of Ptger2 1 0.00 0 0.28
79 INT17091 Il1b Negative_regulation of Localization of Ins1 1 0.32 0.28 0.28
80 INT20035 Il1b Negative_regulation of Gene_expression of LH 1 0.28 0.2 0.22
81 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
82 INT193546 Il1b Positive_regulation of Ephb1 1 0.12 0.35 0.16
83 INT17092 Il1b Regulation of Localization of Ins1 1 0.46 0.13 0.15
84 INT66909 Il1b Regulation of Localization of Avp 1 0.32 0.09 0.15
85 INT139336 Il1b Regulation of Tnfrsf1a 1 0.27 1.3 0.14
86 INT139345 Il1b Positive_regulation of Tnfrsf1b 1 0.11 1.26 0.14
87 INT139337 Il1b Positive_regulation of Positive_regulation of Tnfrsf1b 1 0.12 1.26 0.14
88 INT139341 Positive_regulation of Il1b Positive_regulation of Tnfrsf1b 1 0.11 1.27 0.14
89 INT139344 Negative_regulation of Il1b Positive_regulation of Tnfrsf1b 1 0.10 1.26 0.14
90 INT139340 Il1b Positive_regulation of Positive_regulation of Tnf 1 0.09 1.26 0.14
91 INT139347 Il1b Regulation of Gene_expression of Tnfrsf1a 1 0.27 1.3 0.14
92 INT139343 Il1b Positive_regulation of Nos2 1 0.09 1.26 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24494. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24494. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
2 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
3 INT9347 Localization of Il1b 58 0.81 26.13 31.53
4 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
5 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
6 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
7 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
8 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
9 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
10 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
11 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
12 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
13 INT10705 Binding of Il1b 9 0.36 2.8 5.53
14 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
15 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
16 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
17 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
18 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02
19 INT168275 Phosphorylation of Il1b 1 0.79 2.39 2.01
20 INT9348 Regulation of Localization of Il1b 2 0.27 0.14 1.04
21 INT50989 Regulation of Positive_regulation of Il1b 2 0.42 0.86 1.02
22 INT168280 Positive_regulation of Phosphorylation of Il1b 1 0.49 1.1 0.93
23 INT127822 Negative_regulation of Transcription of Il1b 2 0.42 1.2 0.72
24 INT281991 Regulation of Negative_regulation of Il1b 1 0.03 0.77 0.2
25 INT16046 Regulation of Regulation of Il1b 1 0.45 0 0
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