G:24505

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Official Symbol Ins1
Aliases none
EntrezGene 24505
UniProt Coming Soon
Unique Molecular Interactions 164
Total Molecular Interactions 238
Total Single Events 3287
Unique Interaction Partners 104

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Ins1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Ins1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Ins1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42
2 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
3 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
4 INT18520 Adra2c Positive_regulation of Localization of Ins1 3 0.41 0.63 1.66
5 INT19819 Penk Regulation of Gene_expression of Ins1 1 0.05 0 1.27
6 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
7 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
8 INT37308 Ins1 Regulation of Localization of Gast 1 0.20 0 0.97
9 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
10 INT114546 Ins1 Positive_regulation of Positive_regulation of Trpv1 1 0.39 0.19 0.86
11 INT30422 Penk Regulation of Ins1 1 0.06 0 0.85
12 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
13 INT120149 Positive_regulation of Pomc Positive_regulation of Localization of Ins1 1 0.03 0.09 0.82
14 INT41108 Adarb1 Positive_regulation of Localization of Ins1 1 0.03 0 0.81
15 INT114547 Ins1 Positive_regulation of Trpv1 1 0.36 0.19 0.77
16 INT19818 Penk Positive_regulation of Gene_expression of Ins1 1 0.32 0 0.74
17 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
18 INT101442 Penk Positive_regulation of Localization of Ins1 1 0.29 0.9 0.73
19 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
20 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71
21 INT27690 Ins1 Negative_regulation of GYPA 1 0.00 0.73 0.69
22 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
23 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
24 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
25 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
26 INT321300 Ins1 Negative_regulation of Pck1 1 0.09 0.52 0.59
27 INT321285 Ins1 Negative_regulation of G6pc 1 0.07 0.52 0.59
28 INT94240 Binding of Cp and Ins1 1 0.02 0.7 0.58
29 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54
30 INT80833 Oxt Regulation of Ins1 1 0.04 0 0.53
31 INT80835 Oxt Positive_regulation of Regulation of Ins1 1 0.04 0 0.53
32 INT30028 Ins1 Regulation of Odc1 2 0.11 0 0.51
33 INT31712 Ptger2 Positive_regulation of Localization of Ins1 1 0.13 0.06 0.49
34 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44
35 INT12139 Ins1 Regulation of Gad1 1 0.15 0.33 0.42
36 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
37 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
38 INT64640 Ins1 Regulation of LH 1 0.13 0.38 0.4
39 INT153422 Ins1 Regulation of Transcription of Qrfp 1 0.08 0.23 0.4
40 INT64642 Ins1 Positive_regulation of Localization of Gnrh1 1 0.06 0.44 0.39
41 INT12767 Ins1 Positive_regulation of Phosphorylation of Prkcg 1 0.36 0 0.38
42 INT40395 Ins1 Positive_regulation of Localization of Avp 1 0.16 0.09 0.38
43 INT64641 Ins1 Positive_regulation of Gnrh1 1 0.06 0.44 0.38
44 INT67031 Ins1 Regulation of Etf1 1 0.01 0.69 0.37
45 INT31713 Adra2c Regulation of Localization of Ins1 1 0.22 0.31 0.35
46 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
47 INT37311 Ins1 Regulation of Gast 1 0.05 0 0.33
48 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
49 INT178910 Ins1 Negative_regulation of Gene_expression of Pck1 1 0.04 0.34 0.31
50 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
51 INT17929 Vip Regulation of Localization of Ins1 1 0.07 0 0.3
52 INT26737 Alox5 Regulation of Localization of Ins1 1 0.06 0.09 0.3
53 INT26738 Ca2 Positive_regulation of Localization of Ins1 1 0.12 0.09 0.3
54 INT17930 Calcb Regulation of Localization of Ins1 1 0.05 0 0.3
55 INT57362 Ins1 Positive_regulation of Prkcg Positive_regulation of NA 1 0.01 0.07 0.29
56 INT57363 Ins1 Positive_regulation of NA 1 0.01 0.07 0.29
57 INT280612 Binding of Il6 and Ins1 1 0.05 0.55 0.29
58 INT105877 Positive_regulation of Binding of Ins1 and Oprm1 1 0.21 0.67 0.28
59 INT17091 Il1b Negative_regulation of Localization of Ins1 1 0.32 0.28 0.28
60 INT120975 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.19 0.75 0.27
61 INT37309 Ins1 Negative_regulation of Localization of Gcg 1 0.12 0 0.27
62 INT46500 Ins1 Positive_regulation of Odc1 1 0.27 0 0.27
63 INT105872 Binding of Ins1 and Oprm1 1 0.16 0.58 0.27
64 INT65946 Ins1 Positive_regulation of Atp2b4 1 0.20 0.46 0.25
65 INT120974 Pomc Positive_regulation of Gene_expression of Ins1 1 0.11 0.42 0.25
66 INT214366 Ins1 Regulation of Slc6a3 1 0.11 0.09 0.25
67 INT24105 Gal Negative_regulation of Localization of Ins1 4 0.41 0.06 0.23
68 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
69 INT120976 Pomc Regulation of Ins1 1 0.10 0.47 0.23
70 INT41024 Nts Negative_regulation of Ins1 1 0.14 0.22 0.22
71 INT321979 Negative_regulation of Klk1c8 Negative_regulation of Positive_regulation of Ins1 1 0.04 0.81 0.22
72 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22
73 INT139903 Ins1 Positive_regulation of Gpr83 1 0.13 1.43 0.22
74 INT355103 Binding of Ins2 and Ins1 1 0.12 2 0.21
75 INT321286 Ins1 Negative_regulation of Transcription of G6pc 1 0.05 0.19 0.2
76 INT25951 Ins1 Regulation of Avp 1 0.16 0.15 0.19
77 INT99440 Fglu Positive_regulation of Localization of Ins1 1 0.01 0.18 0.17
78 INT69533 Ins1 Positive_regulation of Localization of LH 1 0.01 0.49 0.17
79 INT34949 Ins1 Positive_regulation of Negative_regulation of B3gat3 1 0.01 0.49 0.17
80 INT34950 Ins1 Positive_regulation of B3gat3 1 0.01 0.49 0.17
81 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16
82 INT59744 Glp1r Regulation of Localization of Ins1 1 0.07 0.14 0.16
83 INT303743 Positive_regulation of Binding of Ins1 and Chrm1 1 0.07 1.04 0.15
84 INT25149 Gnrhr Regulation of Localization of Ins1 1 0.21 0.1 0.15
85 INT17092 Il1b Regulation of Localization of Ins1 1 0.46 0.13 0.15
86 INT303744 Binding of Chrm3 and Ins1 1 0.04 1.03 0.15
87 INT303746 Binding of Ins1 and Chrm1 1 0.05 1.03 0.15
88 INT303745 Positive_regulation of Binding of Chrm3 and Ins1 1 0.05 1.04 0.15
89 INT25150 Gh1 Regulation of Localization of Ins1 1 0.29 0.1 0.15
90 INT205555 Sst Negative_regulation of Ins1 1 0.05 0.77 0.14
91 INT50608 Cpa5 Regulation of Ins1 1 0.02 0 0.14
92 INT50609 Ugt1a5 Regulation of Ins1 1 0.07 0 0.14
93 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14
94 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12
95 INT50610 Cpa5 Positive_regulation of Localization of Ins1 1 0.12 0 0.12
96 INT14775 F8 Negative_regulation of Ins1 1 0.48 0 0.12
97 INT64590 Gnrhr Positive_regulation of Positive_regulation of Ins1 1 0.14 0.33 0.12
98 INT31714 Hrh1 Positive_regulation of Localization of Ins1 1 0.00 0.36 0.11
99 INT14667 Slc3a2 Regulation of Localization of Ins1 1 0.01 0 0.11
100 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11
101 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11
102 INT257873 Ins1 Positive_regulation of Pik3cg 1 0.13 1.05 0.11
103 INT43966 Ins1 Negative_regulation of Gh1 1 0.09 0.33 0.1
104 INT52893 Ins1 Positive_regulation of Localization of Sst 1 0.29 0.17 0.09
105 INT56111 Ins1 Regulation of Localization of Gip 1 0.13 0.23 0.09
106 INT25950 Ins1 Regulation of Crh 1 0.14 0.07 0.09
107 INT24111 GRP Negative_regulation of Localization of Ins1 1 0.08 0 0.09
108 INT330855 Binding of Ins1 and Tgs1 1 0.02 0.86 0.09
109 INT52894 Gcg Negative_regulation of Ins1 1 0.16 0.18 0.09
110 INT46501 Positive_regulation of Ins1 Positive_regulation of Odc1 1 0.27 0 0.09
111 INT306241 Ins1 Negative_regulation of Gene_expression of PCK1 1 0.00 0.91 0.08
112 INT24110 GRP Negative_regulation of Ins1 1 0.08 0 0.08
113 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
114 INT131149 Rxfp2 Positive_regulation of Localization of Ins1 1 0.23 0 0.07
115 INT13148 Avp Positive_regulation of Localization of Ins1 1 0.07 0.05 0.06
116 INT46528 Binding of Ins1 and Gcg 1 0.25 0.07 0.06
117 INT46529 Gcg Positive_regulation of Ins1 1 0.34 0.07 0.06
118 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05
119 INT229711 Positive_regulation of Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05
120 INT173477 Bcar1 Regulation of Localization of Ins1 1 0.16 0.07 0.05
121 INT229712 Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05
122 INT306238 Tead1 Regulation of Ins1 1 0.00 1.04 0.05
123 INT235313 Cyp3a23/3a1 Positive_regulation of Ins1 1 0.14 0.82 0.05
124 INT150048 Ins1 Positive_regulation of Rps6kb1 2 0.23 0.83 0.04
125 INT257878 Ins1 Positive_regulation of Gene_expression of Ntrk2 1 0.00 0.65 0.04
126 INT257877 Ins1 Positive_regulation of Phosphorylation of Ntrk2 1 0.00 0.66 0.04
127 INT278250 Binding of PCOS1 and Ins1 1 0.00 1.23 0.04
128 INT238315 Binding of Ins1 and Hypism 1 0.00 0.37 0.04
129 INT240809 Glp1r Positive_regulation of Localization of Ins1 1 0.15 0.16 0.04
130 INT257881 Ins1 Positive_regulation of Mtor 1 0.05 0.37 0.04
131 INT321294 Ins1 Positive_regulation of Trh 1 0.00 0.08 0.04
132 INT24108 Gal Negative_regulation of Ins1 1 0.41 0 0.04
133 INT179951 Binding of PIK3CA and Ins1 1 0.39 0.32 0.03
134 INT24104 Gip Positive_regulation of Localization of Ins1 1 0.39 0 0.03
135 INT246136 Binding of Ins1 and Capn10 1 0.14 0.86 0.03
136 INT257880 Ins1 Positive_regulation of Phosphorylation of Rraga 1 0.01 0.68 0.03
137 INT348222 Binding of Ins1 and Glp1r 1 0.05 0.82 0.03
138 INT179949 Binding of Ins1 and Irs1 1 0.31 0.32 0.03
139 INT319700 Ins1 Negative_regulation of Lipe 1 0.04 1.22 0.03
140 INT280619 Ins1 Positive_regulation of Srebf1 1 0.04 0.16 0
141 INT289928 Ctrc Negative_regulation of Protein_catabolism of Ins1 1 0.01 0 0
142 INT24114 GRP Regulation of Localization of Ins1 1 0.09 0 0
143 INT275756 xn Regulation of Ins1 1 0.01 3.25 0
144 INT275733 Igfbp3 Regulation of Ins1 1 0.03 0.16 0
145 INT355409 Ins1 Regulation of Transcription of Rax 1 0.00 0.09 0
146 INT321367 Positive_regulation of Ins1 Negative_regulation of Fig4 Positive_regulation of Nr0b2 1 0.02 0.16 0
147 INT246140 Ins1 Positive_regulation of Transcription of Capn10 1 0.19 0.76 0
148 INT97461 2361ex4-5 Positive_regulation of Localization of Ins1 1 0.05 0.1 0
149 INT257871 Binding of Ins1 and Positive_regulation of Trib3 1 0.01 0.49 0
150 INT275747 xn Positive_regulation of Gene_expression of Ins1 1 0.01 0 0
151 INT275759 Binding of xn and Ins1 1 0.01 1.95 0
152 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0
153 INT288214 Lep Negative_regulation of Gene_expression of Ins1 1 0.35 0.05 0
154 INT275748 xn Positive_regulation of Regulation of Ins1 1 0.01 0 0
155 INT275750 xn Regulation of Gene_expression of Ins1 1 0.01 0.11 0
156 INT19288 Il4i1 Positive_regulation of Localization of Ins1 1 0.32 0.26 0
157 INT24107 Gal Regulation of Localization of Ins1 1 0.44 0 0
158 INT150049 Ins1 Positive_regulation of Eif4ebp1 1 0.24 0.46 0
159 INT24106 Grp Regulation of Localization of Ins1 1 0.33 0 0
160 INT275749 Gopc Positive_regulation of Gene_expression of Ins1 1 0.01 0 0
161 INT246139 Ins1 Regulation of Transcription of Capn10 1 0.18 0.76 0
162 INT356349 Ins1 Positive_regulation of Lpl 1 0.10 0.45 0
163 INT275757 xn Positive_regulation of Ins1 1 0.01 0 0
164 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0
165 INT246138 Ins1 Positive_regulation of Capn10 1 0.19 0.75 0
166 INT246709 Ins1 Regulation of Cebpz 1 0.05 1.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24505. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24505. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1114 Localization of Ins1 748 0.80 192.95 165.48
2 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36
3 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76
4 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37
5 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14
6 INT2276 Regulation of Ins1 234 0.61 103.78 54.05
7 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94
8 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07
9 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36
10 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07
11 INT2578 Binding of Ins1 74 0.48 33.57 12.92
12 INT12762 Negative_regulation of Positive_regulation of Ins1 24 0.59 8.51 8.28
13 INT2217 Positive_regulation of Positive_regulation of Ins1 21 0.69 7.66 6.32
14 INT17425 Regulation of Gene_expression of Ins1 23 0.45 18.99 5.61
15 INT2579 Protein_catabolism of Ins1 43 0.99 9.91 5.14
16 INT21606 Positive_regulation of Regulation of Ins1 8 0.41 3.9 2.97
17 INT4329 Regulation of Regulation of Ins1 10 0.61 3.17 2.72
18 INT10267 Regulation of Positive_regulation of Ins1 11 0.24 2.74 2.63
19 INT139896 Phosphorylation of Ins1 29 0.77 24.03 2.35
20 INT2581 Regulation of Binding of Ins1 7 0.61 2.05 2.08
21 INT20509 Positive_regulation of Negative_regulation of Ins1 7 0.48 2.8 1.46
22 INT21652 Negative_regulation of Negative_regulation of Ins1 7 0.39 4.16 1.46
23 INT81733 Transcription of Ins1 9 0.50 6.27 1.41
24 INT10266 Negative_regulation of Regulation of Ins1 9 0.43 3.68 1.28
25 INT2580 Negative_regulation of Protein_catabolism of Ins1 8 0.58 1.34 0.81
26 INT39105 Positive_regulation of Protein_catabolism of Ins1 5 0.61 2.01 0.75
27 INT130279 Positive_regulation of Transcription of Ins1 1 0.24 0.1 0.73
28 INT96602 Positive_regulation of Binding of Ins1 4 0.65 1.59 0.7
29 INT137414 Regulation of Negative_regulation of Ins1 2 0.28 1.84 0.6
30 INT39106 Regulation of Protein_catabolism of Ins1 2 0.37 1.02 0.54
31 INT226594 Positive_regulation of Phosphorylation of Ins1 6 0.22 6.42 0.48
32 INT348775 Negative_regulation of Phosphorylation of Ins1 1 0.19 3.52 0.44
33 INT57643 Negative_regulation of Binding of Ins1 6 0.43 3.51 0.43
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