G:24514

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Official Symbol Jak2
Aliases none
EntrezGene 24514
UniProt Coming Soon
Unique Molecular Interactions 14
Total Molecular Interactions 15
Total Single Events 47
Unique Interaction Partners 9

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Jak2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Jak2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Jak2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
2 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
3 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
4 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
5 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
6 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
7 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
8 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
9 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
10 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
11 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
12 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
13 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
14 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24514. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24514. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
2 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
3 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
4 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
5 INT169336 Binding of Jak2 2 0.42 1.31 0.93
6 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
7 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
8 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
9 INT107462 Localization of Jak2 2 0.60 0.78 0.4
10 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
11 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
12 INT202420 Transcription of Jak2 1 0.56 0.91 0
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