G:24613

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Official Symbol Oprd1
Aliases none
EntrezGene 24613
UniProt Coming Soon
Unique Molecular Interactions 170
Total Molecular Interactions 214
Total Single Events 2516
Unique Interaction Partners 124

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Oprd1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Oprd1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Oprd1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28
2 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
3 INT249566 Binding of Oprd1 and Psmd1 1 0.01 0.82 3.8
4 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
5 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
6 INT69665 Binding of Oprd1 and Pnoc 5 0.35 0.4 2.5
7 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 0.01 0.66 2.5
8 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
9 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
10 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93
11 INT68273 G2e3 Negative_regulation of Binding of Oprd1 and G2e3 1 0.00 0.11 1.93
12 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
13 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82
14 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74
15 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
16 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
17 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
18 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64
19 INT61674 Gpm6a Regulation of Oprd1 1 0.01 0.07 1.62
20 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
21 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
22 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
23 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
24 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
25 INT249565 Binding of Gabrg1 and Oprd1 1 0.00 0.1 1.33
26 INT13756 Binding of Oprd1 and Scn4a 1 0.02 0 1.32
27 INT13755 Binding of Oprd1 and Ap2m1 1 0.20 0 1.32
28 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27
29 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23
30 INT13203 Oprd1 Negative_regulation of Akr1d1 1 0.01 0 1.18
31 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
32 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15
33 INT21267 Cck Negative_regulation of Binding of Oprd1 1 0.50 0 1.12
34 INT60783 Binding of Oprd1 and Cck 1 0.26 0.47 1.09
35 INT121089 Binding of Oprd1 and Adarb1 2 0.06 0 1.07
36 INT6415 Binding of Cpe and Oprd1 1 0.00 0 1.07
37 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
38 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04
39 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
40 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01
41 INT18890 Penk Regulation of Oprd1 1 0.25 0.45 0.97
42 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
43 INT82124 IK Positive_regulation of Gene_expression of Oprd1 1 0.00 0 0.92
44 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 0.01 0 0.91
45 INT34273 WAS Regulation of Oprd1 1 0.00 0 0.91
46 INT61317 Positive_regulation of Oprd1 Positive_regulation of Gene_expression of Coq10a 1 0.01 0.39 0.91
47 INT34272 WAS Positive_regulation of Oprd1 1 0.01 0 0.91
48 INT54188 Agp2 Negative_regulation of Binding of Oprd1 and Pag1 1 0.00 0.18 0.91
49 INT54196 Binding of Oprd1 and Agp2 1 0.00 0.18 0.91
50 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9
51 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
52 INT86589 Oprd1 Regulation of Localization of Pomc 1 0.18 0 0.9
53 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
54 INT54187 Gnai1 Negative_regulation of Binding of Oprd1 and Pag1 1 0.00 0.18 0.9
55 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
56 INT161916 Binding of POMC and Oprd1 1 0.01 0 0.89
57 INT161917 Negative_regulation of Binding of POMC and Oprd1 1 0.01 0 0.89
58 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89
59 INT54194 Binding of Oprd1 and Pag1 1 0.01 0.18 0.89
60 INT82125 IK Regulation of Gene_expression of Oprd1 1 0.00 0 0.88
61 INT80792 Prkcg Regulation of Oprd1 1 0.19 0.2 0.86
62 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86
63 INT21534 Binding of Oprd1 and Il1 1 0.00 0 0.84
64 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
65 INT84414 Folr2 Regulation of Binding of Oprd1 1 0.03 0.18 0.84
66 INT113972 Regulation of Binding of Oprd1 and Smu1 1 0.00 0.45 0.84
67 INT113971 Binding of Oprd1 and Smu1 1 0.00 0.45 0.84
68 INT150348 Oprd1 Regulation of Pat 1 0.01 0.38 0.81
69 INT112842 Positive_regulation of Binding of Pdyn and Oprd1 1 0.00 0 0.81
70 INT112841 Binding of Pdyn and Oprd1 1 0.00 0 0.81
71 INT50793 Oprd1 Regulation of Phosphorylation of Oprd1 1 0.00 0 0.8
72 INT21543 Binding of Oprd1 and Cish 2 0.09 0.15 0.78
73 INT77526 Oprd1 Regulation of Positive_regulation of Odc1 1 0.01 0.12 0.78
74 INT90750 Oprd1 Regulation of Positive_regulation of Gpd1 1 0.10 0.25 0.78
75 INT102841 Pdcl Regulation of Oprd1 1 0.02 0.12 0.77
76 INT74829 Oprd1 Regulation of Slc1a2 1 0.17 0 0.76
77 INT15344 Oprd1 Regulation of Localization of Tacr3 1 0.00 0 0.76
78 INT83868 Oprd1 Positive_regulation of Gene_expression of Fos 1 0.01 0 0.75
79 INT114281 Binding of Oprd1 and Nacc1 1 0.03 0 0.74
80 INT93709 Positive_regulation of Oprd1 Regulation of Calm3 1 0.01 0 0.74
81 INT61050 Oprd1 Positive_regulation of Odc1 1 0.25 0 0.74
82 INT93708 Oprd1 Regulation of Calm3 1 0.01 0 0.73
83 INT7049 Binding of YY1 and Oprd1 1 0.01 0 0.73
84 INT87274 CALM1 Regulation of Oprd1 1 0.01 0.08 0.72
85 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72
86 INT72689 Binding of Oprd1 and Ptprg 1 0.00 0.38 0.71
87 INT29048 Oprd1 Regulation of Etf1 1 0.00 0 0.71
88 INT71815 Coq10a Regulation of Oprd1 1 0.00 0.15 0.7
89 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
90 INT150067 Cnr1 Regulation of Gene_expression of Oprd1 1 0.01 0.23 0.69
91 INT122028 Binding of IFNA1 and Oprd1 1 0.01 0.41 0.69
92 INT122029 Binding of Oprd1 and Positive_regulation of IFNA1 1 0.01 0.4 0.68
93 INT33274 Binding of Oprd1 and Igh-6 1 0.12 0 0.66
94 INT70161 Casp1 Regulation of Oprd1 1 0.03 0 0.65
95 INT111014 Binding of OPRL1 and Oprd1 1 0.02 0 0.64
96 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
97 INT90924 Oprd1 Regulation of Binding of Fgfr1op2 1 0.01 0 0.63
98 INT43321 Oprd1 Regulation of Ap2m1 1 0.20 0 0.63
99 INT31942 Binding of FCGR1A and Oprd1 1 0.00 0 0.62
100 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
101 INT59687 Gene_expression of Opcml Regulation of Binding of Oprd1 1 0.00 0.54 0.62
102 INT52018 Oprd1 Regulation of Gene_expression of C10orf10 1 0.00 0 0.61
103 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
104 INT56859 Oprd1 Positive_regulation of OPRD1 1 0.01 0.22 0.61
105 INT52817 Oprd1 Regulation of Gnrh1 1 0.11 0.17 0.61
106 INT52820 Oprd1 Regulation of NR3C1 1 0.02 0.17 0.61
107 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
108 INT76458 Binding of Oprd1 and Coq10a 1 0.01 0.08 0.6
109 INT20684 Binding of Oprd1 and Gnrh1 1 0.17 0 0.57
110 INT78580 Binding of Adra2b and Oprd1 1 0.01 0.07 0.57
111 INT60665 Il1b Regulation of Oprd1 1 0.05 0 0.57
112 INT142868 YY1 Positive_regulation of Oprd1 1 0.01 0.1 0.55
113 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
114 INT18116 NPC1 Negative_regulation of Binding of NPC1 and Oprd1 1 0.13 0 0.54
115 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54
116 INT160793 Regulation of Binding of Oprd1 and Pvalb 1 0.03 0 0.53
117 INT160792 Binding of Oprd1 and Pvalb 1 0.02 0 0.53
118 INT60759 Ikbip Regulation of Gene_expression of Oprd1 1 0.01 0 0.52
119 INT166862 Kcnj6 Positive_regulation of Gene_expression of Oprd1 1 0.15 0 0.52
120 INT90067 Binding of Oprd1 and Npff 1 0.20 0.09 0.52
121 INT33505 Oprd1 Regulation of Localization of CGA 1 0.00 0 0.52
122 INT166864 Kcnj9 Positive_regulation of Gene_expression of Oprd1 1 0.07 0 0.52
123 INT126654 Oprd1 Regulation of Oprm1 1 0.03 0.13 0.52
124 INT85565 Oprd1 Regulation of KCNJ6 1 0.00 0 0.51
125 INT25524 Oprd1 Regulation of Localization of GCG 1 0.01 0.52 0.48
126 INT264975 BOC Negative_regulation of Localization of Oprd1 1 0.01 0.17 0.48
127 INT16677 Binding of Avp and Oprd1 1 0.02 0.8 0.47
128 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
129 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
130 INT151483 Negative_regulation of Binding of Oprd1 and Penk 1 0.02 0 0.47
131 INT64217 Oprm1 Positive_regulation of Oprd1 1 0.24 0 0.46
132 INT66890 Binding of PENK and Oprd1 1 0.05 0 0.45
133 INT13364 Binding of Oprd1 and Rbm39 1 0.00 0 0.45
134 INT31707 Binding of Oprd1 and Fads1 1 0.01 0 0.44
135 INT27997 Oprd1 Positive_regulation of Localization of Me1 1 0.03 0 0.44
136 INT31706 Binding of Oprd1 and Slc3a1 1 0.01 0 0.43
137 INT66196 OPRK1 Negative_regulation of Oprd1 1 0.00 0 0.43
138 INT134114 Gnai2 Positive_regulation of Oprd1 Regulation of ADCY1 1 0.00 0.47 0.41
139 INT77924 Binding of SCD and Oprd1 1 0.00 0.25 0.4
140 INT18270 Binding of Oprd1 and Pomc 1 0.30 0 0.4
141 INT77923 Negative_regulation of Binding of SCD and Oprd1 1 0.00 0.25 0.4
142 INT157646 Positive_regulation of Oprd1 Positive_regulation of Phosphorylation of Prkcc 1 0.01 0 0.4
143 INT157647 Positive_regulation of Oprd1 Positive_regulation of Pik3c3 1 0.01 0 0.4
144 INT57649 Oprd1 Positive_regulation of Npr1 1 0.01 0.1 0.39
145 INT90807 EGF Positive_regulation of Oprd1 1 0.00 0.39 0.39
146 INT131180 Binding of Grin1 and Oprd1 1 0.24 0 0.39
147 INT59443 Oprd1 Positive_regulation of Gtf3a 1 0.06 0 0.39
148 INT67445 Oprd1 Regulation of Localization of POMC 1 0.00 0 0.39
149 INT67287 Negative_regulation of Binding of Oprd1 and Oprm1 1 0.03 0.18 0.37
150 INT68119 Binding of IL2 and Oprd1 1 0.02 0 0.37
151 INT67443 Oprd1 Regulation of Ugt1a10 1 0.00 0 0.36
152 INT21286 Binding of Oprd1 and Pck1 1 0.08 0 0.34
153 INT79383 Pde1b Regulation of Oprd1 1 0.02 0 0.34
154 INT50069 Binding of Oprl1 and Oprd1 1 0.02 0 0.32
155 INT30057 Positive_regulation of Binding of Oprd1 and Penk 1 0.35 0.61 0.32
156 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
157 INT29119 Nts Regulation of Oprd1 1 0.18 0.79 0.31
158 INT29118 Trh Regulation of Oprd1 1 0.24 0.79 0.31
159 INT334737 Binding of Oprd1 and Gpi 1 0.01 0.71 0.28
160 INT32157 Binding of TNFRSF10B and Oprd1 1 0.01 0 0.27
161 INT32156 Binding of ENG and Oprd1 1 0.00 0 0.26
162 INT132170 PSG7 Positive_regulation of Positive_regulation of Oprd1 1 0.00 0 0.26
163 INT82194 Dbi Regulation of Oprd1 1 0.12 0.07 0.26
164 INT74043 Negative_regulation of Oprd1 Negative_regulation of Localization of GHRH 1 0.02 0 0.25
165 INT74042 Negative_regulation of Oprd1 Negative_regulation of Localization of GH1 1 0.01 0 0.25
166 INT74044 GHRH Positive_regulation of Localization of Oprd1 1 0.02 0 0.25
167 INT98379 Regulation of Binding of Pomc and Oprd1 1 0.01 0.35 0.23
168 INT98380 Binding of Pomc and Oprd1 1 0.02 0.35 0.23
169 INT42608 Pomc Positive_regulation of Oprd1 1 0.27 0 0.17
170 INT5521 Oprd1 Negative_regulation of Gene_expression of Crh 1 0.11 0.43 0.16
171 INT5516 Oprd1 Negative_regulation of Crh 1 0.15 0.43 0.16
172 INT226708 Oprd1 Positive_regulation of Tsg101 1 0.00 0.3 0.1
173 INT226709 Oprd1 Positive_regulation of Vps28 1 0.00 0.3 0.1
174 INT89016 Oprd1 Negative_regulation of Drd1a 1 0.06 0 0
175 INT87158 Pmf1 Positive_regulation of Gene_expression of Oprd1 1 0.08 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24613. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24613. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5660 Binding of Oprd1 477 0.48 71.86 342.06
2 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32
3 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41
4 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9
5 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11
6 INT12569 Localization of Oprd1 94 0.81 23.81 104.56
7 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54
8 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12
9 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58
10 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22
11 INT6382 Regulation of Binding of Oprd1 36 0.61 7 26.48
12 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52
13 INT31393 Positive_regulation of Localization of Oprd1 10 0.66 7.32 21.23
14 INT27529 Phosphorylation of Oprd1 23 0.47 1.16 20.18
15 INT31905 Positive_regulation of Binding of Oprd1 21 0.66 3.31 18.44
16 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63
17 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34
18 INT31394 Negative_regulation of Localization of Oprd1 3 0.39 2.38 7.89
19 INT20845 Positive_regulation of Negative_regulation of Oprd1 7 0.70 1.81 7.33
20 INT6239 Regulation of Regulation of Oprd1 7 0.45 0.34 7.26
21 INT5311 Regulation of Negative_regulation of Oprd1 11 0.43 0.99 7.23
22 INT91575 Positive_regulation of Phosphorylation of Oprd1 8 0.02 0.23 6.07
23 INT26555 Regulation of Positive_regulation of Oprd1 6 0.59 2.47 5.76
24 INT23738 Regulation of Transcription of Oprd1 6 0.26 0.48 4.3
25 INT29671 Regulation of Localization of Oprd1 4 0.24 1.04 3.92
26 INT41296 Protein_catabolism of Oprd1 8 0.85 0.79 3.48
27 INT82035 Negative_regulation of Phosphorylation of Oprd1 3 0.13 0 3.16
28 INT28729 Negative_regulation of Negative_regulation of Oprd1 3 0.43 0.33 2.79
29 INT16715 Positive_regulation of Transcription of Oprd1 3 0.66 0.6 2.74
30 INT50776 Regulation of Phosphorylation of Oprd1 1 0.01 0 1.3
31 INT80966 Negative_regulation of Transcription of Oprd1 1 0.59 0 1.07
32 INT99640 Positive_regulation of Regulation of Oprd1 1 0.28 0 0.6
33 INT67286 Negative_regulation of Regulation of Oprd1 1 0.40 0.18 0.37
34 INT226706 Positive_regulation of Protein_catabolism of Oprd1 1 0.01 0.3 0.1
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