G:24664

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Official Symbol Pomc
Aliases Pomc1, Pomc2, alphaMSH
EntrezGene 24664
UniProt Coming Soon
Unique Molecular Interactions 187
Total Molecular Interactions 326
Total Single Events 3211
Unique Interaction Partners 78

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Pomc. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Pomc. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Pomc. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
2 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
3 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
4 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
5 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
6 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
7 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
8 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
9 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
10 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16
11 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07
12 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
13 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
14 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9
15 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
16 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
17 INT32412 Penk Regulation of Pomc 3 0.21 0.36 1.62
18 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
19 INT41652 Binding of Pomc and Oprl1 3 0.16 0 1.57
20 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
21 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
22 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
23 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
24 INT1314 Pomc Regulation of Localization of Gnrhr 2 0.16 0.14 1.45
25 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
26 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
27 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38
28 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
29 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
30 INT34471 Negative_regulation of Pomc Regulation of Slc3a1 1 0.05 0.12 1.24
31 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
32 INT34473 Pomc Regulation of Slc3a1 1 0.03 0.07 1.23
33 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21
34 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
35 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
36 INT61053 Adarb1 Positive_regulation of Pomc Negative_regulation of Odc1 1 0.01 0 1.1
37 INT57508 Pomc Negative_regulation of Adarb1 1 0.01 0.22 1.05
38 INT58807 Pomc Negative_regulation of Localization of LH 2 0.06 0 1.02
39 INT22109 Positive_regulation of Pomc Positive_regulation of Penk 1 0.35 0 0.99
40 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
41 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94
42 INT1654 Pomc Regulation of DSP 1 0.03 0 0.94
43 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
44 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
45 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
46 INT86589 Oprd1 Regulation of Localization of Pomc 1 0.18 0 0.9
47 INT56779 Pomc Negative_regulation of Gene_expression of Odc1 2 0.31 0 0.89
48 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
49 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
50 INT31495 Pomc Regulation of Localization of Gnrh1 2 0.04 0 0.86
51 INT40742 Pomc Regulation of Localization of Gh1 1 0.37 0 0.86
52 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81
53 INT40743 Binding of Gh1 and Pomc 1 0.22 0 0.8
54 INT9527 Avp Positive_regulation of Localization of Pomc 7 0.58 0.29 0.77
55 INT29913 Binding of FANCB and Pomc 1 0.01 0 0.76
56 INT164057 POMC Regulation of Pomc 1 0.09 0.3 0.75
57 INT41455 Binding of Pomc and Pdyn 1 0.04 0 0.75
58 INT40826 Pomc Negative_regulation of Binding of Sstr1 1 0.05 0 0.74
59 INT164052 Agrp Regulation of Pomc 1 0.16 0.29 0.73
60 INT45305 Pomc Positive_regulation of Localization of Avp 1 0.12 0 0.73
61 INT9290 Pomc Regulation of Prl 2 0.09 0.69 0.71
62 INT29324 Trmt2a Negative_regulation of Binding of Pomc 1 0.00 0 0.71
63 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71
64 INT1312 Pomc Positive_regulation of Gnrhr 2 0.11 0.22 0.7
65 INT82378 Sst Regulation of Localization of Pomc 1 0.23 0.6 0.7
66 INT135119 Binding of Pomc and Crh 1 0.35 0 0.67
67 INT40311 Regulation of Binding of Pomc and Penk 1 0.23 0 0.64
68 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
69 INT32241 Pomc Negative_regulation of Pomc Positive_regulation of Penk 1 0.23 0 0.63
70 INT61164 Binding of Pomc and Pcyt1a 1 0.17 0.24 0.61
71 INT77120 Pomc Regulation of HYAL1 1 0.01 0 0.61
72 INT41220 Pomc Negative_regulation of Oxt 1 0.08 0 0.61
73 INT62461 Pomc Regulation of Il2 Positive_regulation of Crh 1 0.12 0.13 0.6
74 INT6723 Negative_regulation of Pomc Positive_regulation of Positive_regulation of Oprm1 1 0.20 0.55 0.6
75 INT56391 Pomc Negative_regulation of Localization of Gh1 1 0.26 0 0.59
76 INT47498 Pomc Positive_regulation of Localization of Oxt 1 0.15 0 0.59
77 INT51510 Pomc Negative_regulation of Penk 1 0.24 0 0.58
78 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
79 INT60374 Il2 Positive_regulation of Pomc 1 0.07 0 0.58
80 INT60372 Il2 Positive_regulation of Localization of Pomc 1 0.08 0 0.58
81 INT41542 Pomc Regulation of Sst 1 0.03 0 0.58
82 INT62445 Pomc Negative_regulation of Localization of Crh 1 0.12 0.07 0.58
83 INT42040 Pomc Regulation of Positive_regulation of Gnrh1 1 0.28 0.46 0.56
84 INT34959 Pomc Positive_regulation of Localization of Vip 1 0.08 0 0.56
85 INT42041 Pomc Regulation of Gnrh1 1 0.17 0.46 0.56
86 INT21568 Oprk1 Regulation of Localization of Pomc 1 0.18 0 0.55
87 INT31215 Sst Negative_regulation of Localization of Pomc 1 0.05 0 0.55
88 INT21567 Oprk1 Regulation of Pomc 1 0.18 0 0.55
89 INT61051 Pomc Negative_regulation of Odc1 1 0.22 0 0.54
90 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
91 INT130157 Pomc Regulation of Gene_expression of Ednrb 1 0.14 0 0.52
92 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
93 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
94 INT9169 Pomc Positive_regulation of Localization of Cck 1 0.29 0 0.5
95 INT135755 Pomc Positive_regulation of Positive_regulation of Id3 1 0.17 0 0.5
96 INT135751 Pomc Positive_regulation of Positive_regulation of Id1 1 0.19 0 0.5
97 INT135752 Pomc Positive_regulation of Id3 1 0.16 0 0.5
98 INT30617 Pomc Regulation of Pdyn 1 0.00 0 0.5
99 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
100 INT135753 Pomc Positive_regulation of Gene_expression of Id1 1 0.17 0 0.5
101 INT55207 Prl Positive_regulation of Localization of Pomc 1 0.07 0 0.5
102 INT135754 Pomc Positive_regulation of Id1 1 0.17 0 0.5
103 INT9291 Regulation of Pomc Regulation of Prl 1 0.05 0.69 0.49
104 INT32597 Pomc Regulation of Gene_expression of Il2 1 0.29 0 0.49
105 INT32714 Pomc Regulation of Localization of LH 1 0.15 0 0.49
106 INT30802 Pomc Negative_regulation of Trh 1 0.11 0 0.48
107 INT30262 Pomc Negative_regulation of Localization of Gnrh1 1 0.26 0.79 0.48
108 INT17603 Cck Negative_regulation of Positive_regulation of Pomc 1 0.35 0 0.46
109 INT32186 Binding of Pomc and Negative_regulation of Localization of LH 1 0.05 0 0.45
110 INT43058 Pomc Regulation of Localization of Rhd 1 0.03 0.19 0.45
111 INT43453 Pomc Negative_regulation of Localization of Avp 1 0.38 0.82 0.45
112 INT34985 Gene_expression of Pomc Positive_regulation of Localization of Trh 1 0.09 0 0.42
113 INT32548 Pomc Positive_regulation of Regulation of Nts 1 0.14 0 0.41
114 INT47595 Binding of POMC and Pomc 1 0.02 0 0.41
115 INT34979 Gene_expression of Pomc Positive_regulation of Localization of Prl 1 0.09 0 0.41
116 INT18270 Binding of Oprd1 and Pomc 1 0.30 0 0.4
117 INT37582 Pomc Regulation of Odc1 1 0.31 0 0.4
118 INT37585 Pomc Regulation of Pomc Regulation of Odc1 1 0.24 0 0.4
119 INT40744 Pomc Regulation of Binding of Gh1 and Pomc 1 0.11 0 0.4
120 INT32716 Pomc Negative_regulation of LH 1 0.11 0 0.39
121 INT51341 Binding of Pomc and Clu 1 0.14 0 0.38
122 INT28991 Tmpo Positive_regulation of Gene_expression of Pomc 1 0.34 0.82 0.37
123 INT163572 Pomc Positive_regulation of Oprm1 1 0.06 0.1 0.37
124 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36
125 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36
126 INT32818 Binding of Pomc and Gtf3a 1 0.02 0 0.36
127 INT66368 Pomc Regulation of Positive_regulation of Crh 1 0.36 0 0.35
128 INT66370 Pomc Regulation of Positive_regulation of Fos 1 0.42 0 0.35
129 INT164371 Dbi Regulation of Pomc 1 0.19 0.17 0.35
130 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
131 INT53314 Cck Regulation of Regulation of Pomc 1 0.40 0 0.33
132 INT30523 Pomc Regulation of Oprl1 1 0.06 0.15 0.33
133 INT134490 Binding of Pomc and Sst 1 0.26 0 0.32
134 INT21947 Il1a Positive_regulation of Localization of Pomc 1 0.48 0 0.32
135 INT93464 Hcrt Negative_regulation of Pomc 1 0.18 0 0.31
136 INT21321 Pomc Positive_regulation of LBR 1 0.04 0 0.31
137 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31
138 INT86413 Pomc Regulation of Cor 1 0.01 0.17 0.3
139 INT30265 Binding of Pomc and Gnrh1 1 0.29 0.33 0.29
140 INT89013 Positive_regulation of Gabrd Positive_regulation of Pomc 1 0.21 0.18 0.29
141 INT30264 Binding of Pomc and Gnrhr 1 0.22 0.32 0.29
142 INT104048 Binding of SLC3A2 and Pomc 1 0.05 0 0.28
143 INT53313 Cck Regulation of Pomc 1 0.40 0 0.27
144 INT29914 FANCB Negative_regulation of Binding of Pomc 1 0.01 0 0.27
145 INT153424 Pomc Positive_regulation of Transcription of Qrfp 1 0.02 0.23 0.26
146 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
147 INT120974 Pomc Positive_regulation of Gene_expression of Ins1 1 0.11 0.42 0.25
148 INT42262 Pomc Positive_regulation of POMC 1 0.21 0.35 0.24
149 INT120976 Pomc Regulation of Ins1 1 0.10 0.47 0.23
150 INT29911 Negative_regulation of Binding of Pomc and Penk 1 0.02 0 0.23
151 INT43712 Pomc Regulation of LH 1 0.09 0 0.23
152 INT29257 Pomc Positive_regulation of Gcg 1 0.17 0.23 0.21
153 INT51345 Binding of Vtn and Pomc 1 0.03 0 0.2
154 INT69254 Drd2 Regulation of Gene_expression of Pomc 1 0.01 0 0.2
155 INT71570 Gene_expression of Pomc Negative_regulation of Localization of Prl 1 0.33 0 0.2
156 INT51343 Binding of Pomc and Diablo 1 0.25 0 0.19
157 INT58559 Binding of Pomc and Cdk10 1 0.02 0 0.19
158 INT121045 Crh Regulation of Gene_expression of Pomc 1 0.03 0.16 0.18
159 INT10231 Prl Regulation of Gene_expression of Pomc 1 0.31 0.14 0.18
160 INT121046 Crh Regulation of Localization of Pomc 1 0.03 0.16 0.18
161 INT63443 Binding of Pomc and Il1rl1 1 0.04 0.06 0.18
162 INT42608 Pomc Positive_regulation of Oprd1 1 0.27 0 0.17
163 INT42521 Pomc Regulation of Dbi 1 0.06 0 0.17
164 INT32665 Pomc Negative_regulation of Dbi 1 0.06 0 0.17
165 INT5522 Pomc Negative_regulation of Gene_expression of Crh 1 0.27 0.39 0.16
166 INT222548 Il11 Positive_regulation of Transcription of Pomc 1 0.03 0.7 0.16
167 INT41905 Pomc Negative_regulation of Vip 1 0.46 0 0.15
168 INT41904 Negative_regulation of Pomc Negative_regulation of Vip 1 0.46 0 0.15
169 INT29208 Pomc Regulation of POMC 1 0.01 0.09 0.14
170 INT75374 ecs Positive_regulation of Gene_expression of Pomc 1 0.02 0.64 0.14
171 INT122226 Gh1 Regulation of Gene_expression of Pomc 1 0.01 0 0.12
172 INT222549 Pomc Positive_regulation of Gnrh1 1 0.13 0 0.12
173 INT122227 Pomc Regulation of Gene_expression of LH 1 0.01 0 0.12
174 INT122230 Gnrhr Regulation of Gene_expression of Pomc 1 0.00 0 0.12
175 INT122224 Tshr Regulation of Gene_expression of Pomc 1 0.01 0 0.12
176 INT122238 Fshb Regulation of Gene_expression of Pomc 1 0.01 0 0.12
177 INT122233 Pomc Regulation of Gene_expression of Gnrh1 1 0.01 0 0.12
178 INT51342 Binding of Pomc and Vtn 1 0.23 0 0.1
179 INT24321 Pomc Positive_regulation of Localization of Gli1 1 0.07 0 0.1
180 INT42532 Binding of Pomc and Klk1c2 1 0.21 0 0.09
181 INT222484 Pomc Positive_regulation of Transcription of Prl 1 0.14 0 0.09
182 INT35525 Cck Negative_regulation of Regulation of Pomc 1 0.37 0 0.09
183 INT291007 Pomc Positive_regulation of Ppt1 1 0.14 0.06 0.06
184 INT32743 Oxt Positive_regulation of Localization of Pomc 1 0.00 0.14 0.04
185 INT13343 Binding of Pomc and Adarb1 1 0.00 0.31 0.03
186 INT222565 Crh Positive_regulation of Transcription of Pomc 1 0.10 0.35 0.03
187 INT222500 Avp Positive_regulation of Transcription of Pomc 1 0.17 0.35 0.03
188 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
189 INT35469 Binding of Pomc and Prl 1 0.07 0.17 0
190 INT144317 Regulation of E2f5 Positive_regulation of Pomc 1 0.06 0 0
191 INT144318 E2f5 Positive_regulation of Pomc 1 0.10 0 0
192 INT92728 Dlst Positive_regulation of Pomc 1 0.19 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24664. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24664. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
2 INT1308 Localization of Pomc 457 0.81 66.83 217.5
3 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
4 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
5 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
6 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48
7 INT1463 Binding of Pomc 129 0.48 15.89 56.27
8 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3
9 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97
10 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77
11 INT7565 Transcription of Pomc 69 0.72 14.46 27.41
12 INT9526 Negative_regulation of Localization of Pomc 41 0.58 6.93 23.3
13 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02
14 INT15643 Positive_regulation of Positive_regulation of Pomc 30 0.65 4.59 15.34
15 INT5515 Negative_regulation of Positive_regulation of Pomc 25 0.58 8.73 11.88
16 INT11839 Protein_catabolism of Pomc 15 0.98 0.77 6.99
17 INT32532 Regulation of Positive_regulation of Pomc 11 0.61 3.2 5.93
18 INT7575 Regulation of Transcription of Pomc 8 0.60 1.57 4.59
19 INT10806 Positive_regulation of Transcription of Pomc 13 0.50 1.74 4.58
20 INT22337 Negative_regulation of Transcription of Pomc 12 0.59 2.17 4.32
21 INT14499 Regulation of Regulation of Pomc 7 0.61 0.15 4.06
22 INT30074 Positive_regulation of Negative_regulation of Pomc 7 0.50 0.99 3.58
23 INT34678 Regulation of Negative_regulation of Pomc 8 0.62 1.24 3.47
24 INT5508 Negative_regulation of Negative_regulation of Pomc 10 0.53 1.57 3.22
25 INT13748 Negative_regulation of Regulation of Pomc 4 0.41 0.63 2.5
26 INT6722 Regulation of Binding of Pomc 4 0.45 0.17 1.75
27 INT33245 Negative_regulation of Binding of Pomc 6 0.52 0 1.52
28 INT32575 Negative_regulation of Protein_catabolism of Pomc 1 0.41 0.18 1.42
29 INT23693 Positive_regulation of Protein_catabolism of Pomc 1 0.38 0 1.35
30 INT39580 Positive_regulation of Regulation of Pomc 3 0.49 0 1.33
31 INT30280 Phosphorylation of Pomc 2 0.16 0.13 0.73
32 INT281025 Positive_regulation of Phosphorylation of Pomc 1 0.10 0.14 0.3
33 INT40143 Positive_regulation of Binding of Pomc 1 0.50 0 0.17
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