G:24681

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Official Symbol Prkcg
Aliases PKC, PKCI, Prkc, Prkcc, RATPKCI, MGC105487
EntrezGene 24681
UniProt Coming Soon
Unique Molecular Interactions 134
Total Molecular Interactions 171
Total Single Events 1812
Unique Interaction Partners 97

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Prkcg. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Prkcg. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Prkcg. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
2 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
3 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
4 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
5 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
6 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
7 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
8 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
9 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
10 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
11 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
12 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
13 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
14 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
15 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
16 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
17 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
18 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
19 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
20 INT276688 Positive_regulation of Prkcg Positive_regulation of Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.46
21 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
22 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
23 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
24 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
25 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
26 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
27 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
28 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
29 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
30 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
31 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
32 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
33 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
34 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
35 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
36 INT78976 Prkcg Regulation of Ina 1 0.13 0.16 0.93
37 INT186448 Prkcg Regulation of Trib3 Regulation of Creb1 1 0.02 0.23 0.92
38 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
39 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
40 INT159995 Prkcg Regulation of Gene_expression of Bace1 1 0.39 0.32 0.91
41 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9
42 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
43 INT113383 Negative_regulation of Sert1 Positive_regulation of Prkcg 1 0.31 0 0.89
44 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
45 INT152853 Prkcg Regulation of PRS 1 0.01 0.21 0.87
46 INT80792 Prkcg Regulation of Oprd1 1 0.19 0.2 0.86
47 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
48 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
49 INT240456 Ephb1 Regulation of Prkcg 1 0.19 0.51 0.79
50 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
51 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
52 INT152831 Nefh Regulation of Prkcg 1 0.05 0.19 0.77
53 INT152836 Nefm Regulation of Prkcg 1 0.15 0.19 0.77
54 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
55 INT152854 PRS Regulation of Prkcg 1 0.01 0.19 0.76
56 INT219914 Prkcg Regulation of Phosphorylation of Trpv1 1 0.11 1 0.74
57 INT124353 Prkcg Positive_regulation of Positive_regulation of Gorasp2 1 0.02 1.19 0.73
58 INT351351 Prkcg Regulation of Lpar1 1 0.12 0.58 0.72
59 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
60 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
61 INT171825 Binding of Prkcg and Ncs1 1 0.00 0.07 0.66
62 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
63 INT265144 Olah Positive_regulation of Prkcg 1 0.02 0 0.62
64 INT265140 Olah Regulation of Prkcg 1 0.01 0 0.62
65 INT265187 Olah Regulation of Olah Positive_regulation of Prkcg 1 0.00 0 0.62
66 INT265188 Olah Positive_regulation of Olah Regulation of Prkcg 1 0.00 0 0.62
67 INT131072 Cc2d1b Negative_regulation of Prkcg 1 0.01 0 0.58
68 INT270943 Binding of Prkcg and Cpe 1 0.05 0 0.58
69 INT263230 Prkcg Regulation of Trpv1 1 0.05 0.95 0.56
70 INT78973 Prkcg Positive_regulation of Positive_regulation of Ina 1 0.10 0.07 0.55
71 INT263231 Positive_regulation of Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.55
72 INT263229 Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.54
73 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
74 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
75 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
76 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
77 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
78 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
79 INT330543 Prkcg Regulation of Regulation of Trpm8 1 0.11 0.28 0.47
80 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
81 INT91087 SST Positive_regulation of Positive_regulation of Prkcg 1 0.29 0.05 0.43
82 INT74548 Prkcg Regulation of Tecr 1 0.48 0 0.43
83 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
84 INT69851 Prkcg Regulation of Pigm 1 0.16 0 0.41
85 INT153052 Prkcg Positive_regulation of Phosphorylation of Trpv1 1 0.45 0 0.38
86 INT12767 Ins1 Positive_regulation of Phosphorylation of Prkcg 1 0.36 0 0.38
87 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38
88 INT171823 Nrgn Positive_regulation of Prkcg 1 0.18 0.53 0.36
89 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
90 INT263226 Prkcg Negative_regulation of Positive_regulation of Ca2 1 0.01 0.58 0.36
91 INT270936 Prkcg Regulation of Flvcr2 1 0.00 0 0.35
92 INT265146 Calm2 Negative_regulation of Phosphorylation of Prkcg 1 0.04 0.07 0.35
93 INT238261 pma Positive_regulation of Prkcg 1 0.01 0.33 0.34
94 INT265142 Prkcg Regulation of Localization of Chrm1 1 0.04 0 0.34
95 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33
96 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33
97 INT265147 Prkcg Regulation of Gene_expression of Chrm1 1 0.04 0 0.33
98 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32
99 INT126851 Prkcg Positive_regulation of Creb1 1 0.46 0.09 0.32
100 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
101 INT66414 Prkcg Regulation of Penk 1 0.17 0 0.32
102 INT66413 Prkcg Regulation of Positive_regulation of Penk 1 0.38 0 0.32
103 INT57362 Ins1 Positive_regulation of Prkcg Positive_regulation of NA 1 0.01 0.07 0.29
104 INT69854 Prkcg Regulation of Transcription of Pdyn 1 0.00 0 0.28
105 INT69853 Prkcg Regulation of Pdyn 1 0.00 0 0.28
106 INT69852 Prkcg Regulation of Pdyn 1 0.14 0 0.28
107 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28
108 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26
109 INT149947 Ephb1 Positive_regulation of Prkcg 1 0.27 0.07 0.26
110 INT237749 Prkcg Regulation of Transcription of Pcgf1 1 0.14 0.68 0.25
111 INT71429 Calca Positive_regulation of Prkcg 1 0.54 0 0.21
112 INT126046 Binding of Prkcg and Emp1 1 0.33 0.25 0.21
113 INT238222 pma Positive_regulation of Prkcg Negative_regulation of Gene_expression of Cr1l 1 0.01 0.26 0.16
114 INT238262 Prkcg Negative_regulation of Gene_expression of Cr1l 1 0.12 0.26 0.16
115 INT219912 Trpv1 Regulation of Prkcg 1 0.11 0 0.15
116 INT326246 Prkcg Positive_regulation of ras 1 0.01 0.62 0.13
117 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13
118 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
119 INT326247 Prkcg Positive_regulation of Prkaca 1 0.00 0.62 0.13
120 INT237746 Prkcg Regulation of Pcgf1 1 0.14 0.34 0.12
121 INT270957 Prkcg Negative_regulation of Flvcr2 1 0.00 0 0.1
122 INT171400 Binding of Adcyap1 and Prkcg 1 0.01 0.24 0.08
123 INT77938 Prkcg Positive_regulation of Localization of Gnrh1 1 0.32 0 0.08
124 INT275102 Prkcg Regulation of CREB1 1 0.01 0 0.06
125 INT275101 CAMK4 Positive_regulation of Prkcg 1 0.01 0 0.06
126 INT275103 CA2 Positive_regulation of Prkcg 1 0.01 0 0.06
127 INT275105 CALM3 Positive_regulation of Prkcg 1 0.00 0 0.06
128 INT307454 Prkcg Regulation of Phosphorylation of Gsk3a 1 0.04 0.13 0.05
129 INT326250 Prkcg Positive_regulation of ARAF 1 0.00 0 0.05
130 INT171399 Binding of Npr1 and Prkcg 1 0.00 0.23 0.04
131 INT191214 Cotl1 Positive_regulation of Prkcg 1 0.10 1.35 0.04
132 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
133 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
134 INT87159 Phosphorylation of Marcks Positive_regulation of Prkcg 1 0.07 0 0
135 INT87160 Prkcg Regulation of Pmf1 1 0.39 0 0
136 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0
137 INT330049 Prkcg Negative_regulation of Pnck 1 0.01 0.28 0
138 INT143144 Prkcg Negative_regulation of Gene_expression of Acta2 1 0.00 0.15 0
139 INT290899 Prkcg Regulation of Positive_regulation of Nos2 1 0.14 0 0
140 INT290902 Prkcg Regulation of Positive_regulation of Ntn1 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24681. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24681. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
3 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
4 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
5 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
6 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
7 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
8 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
9 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
10 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
11 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
12 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
13 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
14 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
15 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
16 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
17 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
18 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
19 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
20 INT59879 Transcription of Prkcg 9 0.69 2.29 5.3
21 INT65210 Positive_regulation of Binding of Prkcg 6 0.70 2.71 3.65
22 INT74374 Negative_regulation of Phosphorylation of Prkcg 7 0.41 1.28 3.57
23 INT129752 Regulation of Phosphorylation of Prkcg 8 0.31 1.43 3.41
24 INT161863 Positive_regulation of Regulation of Prkcg 4 0.27 1.63 3.1
25 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08
26 INT181668 Protein_catabolism of Prkcg 8 0.77 2.59 3.06
27 INT59878 Negative_regulation of Transcription of Prkcg 3 0.43 2.15 2.85
28 INT59877 Regulation of Regulation of Prkcg 2 0.45 1.17 2.81
29 INT70174 Negative_regulation of Regulation of Prkcg 3 0.42 0.88 1.98
30 INT183568 Negative_regulation of Protein_catabolism of Prkcg 2 0.36 1.12 1.33
31 INT182594 Regulation of Protein_catabolism of Prkcg 1 0.39 0 0.88
32 INT265156 Regulation of Binding of Prkcg 1 0.15 0.18 0.78
33 INT280801 Positive_regulation of Transcription of Prkcg 1 0.07 0.12 0.67
34 INT181674 Positive_regulation of Protein_catabolism of Prkcg 1 0.14 0.37 0.21
35 INT183569 Negative_regulation of Binding of Prkcg 1 0.05 0.69 0
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