G:24683

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Official Symbol Prl
Aliases PRLB, Prol, PRLSD1, Prl1a1, RNPROL, RATPRLSD1
EntrezGene 24683
UniProt Coming Soon
Unique Molecular Interactions 280
Total Molecular Interactions 504
Total Single Events 8626
Unique Interaction Partners 129

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Prl. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Prl. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Prl. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
2 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24
3 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
4 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
5 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
6 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
7 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
8 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1
9 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03
10 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
11 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
12 INT40660 Pdyn Positive_regulation of Localization of Prl 1 0.27 0 3.01
13 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
14 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
15 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
16 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
17 INT6768 Oprl1 Regulation of Localization of Prl 2 0.12 0 1.55
18 INT44505 Mt1a Positive_regulation of Mt1a Positive_regulation of Prl 1 0.19 0 1.48
19 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
20 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
21 INT87812 Penk Regulation of Prl 1 0.16 0 1.34
22 INT777 Prss12 Positive_regulation of Prl 1 0.19 0 1.33
23 INT52205 Prl Positive_regulation of Gene_expression of Penk 1 0.52 0.15 1.25
24 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23
25 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
26 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
27 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09
28 INT40451 Cck Regulation of Prl 1 0.49 0 1.09
29 INT34900 Trh Positive_regulation of Localization of Prl 1 0.05 0 1.09
30 INT17414 TRH Positive_regulation of Prl 4 0.47 0 1.07
31 INT77737 Pnoc Positive_regulation of Localization of Prl 3 0.55 0 1.07
32 INT39485 Prl Negative_regulation of Localization of Gnrh1 2 0.40 0 1.06
33 INT58745 CPP Positive_regulation of Localization of Prl 1 0.01 0.92 1.06
34 INT139752 Ubqln1 Regulation of Localization of Prl 1 0.05 0 1.04
35 INT52562 Lhb Positive_regulation of Prl 3 0.00 1.09 1.02
36 INT13372 Prl Regulation of LH 2 0.25 0.09 0.98
37 INT86960 ADRA1D Negative_regulation of Prl 1 0.00 0 0.97
38 INT40287 OPRM1 Positive_regulation of Negative_regulation of Prl 1 0.00 0.93 0.96
39 INT88583 Hal Positive_regulation of Prl 1 0.15 0.44 0.95
40 INT55204 Prl Positive_regulation of Localization of Dbi 1 0.02 0 0.91
41 INT46972 Amt Positive_regulation of Localization of Prl 1 0.37 0.2 0.91
42 INT32713 Prl Regulation of Localization of Gnrh1 3 0.42 0.17 0.9
43 INT28921 Adra2a Positive_regulation of Localization of Prl 1 0.24 0 0.9
44 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
45 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
46 INT31950 PIF1 Positive_regulation of Localization of Prl 1 0.06 0 0.87
47 INT61410 CTS Positive_regulation of Prl 1 0.02 1.49 0.87
48 INT26529 Prl Regulation of Avp 1 0.08 0.26 0.85
49 INT17416 TRH Positive_regulation of Localization of Prl 1 0.47 0 0.85
50 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
51 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
52 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
53 INT52557 Lhb Regulation of Trh Positive_regulation of Prl 1 0.00 0.14 0.83
54 INT52571 Lhb Regulation of Lhb Positive_regulation of Prl 1 0.00 0.14 0.83
55 INT52558 Lhb Regulation of Trh Regulation of Prl 1 0.00 0.14 0.83
56 INT3432 Vip Positive_regulation of Prl 2 0.45 0 0.82
57 INT52573 Trh Regulation of Trh Regulation of Prl 1 0.00 0.14 0.82
58 INT105249 Cyb5b Positive_regulation of Localization of Prl 1 0.04 0 0.79
59 INT18099 POMC Positive_regulation of Binding of Prl 1 0.00 0 0.76
60 INT52206 Prl Regulation of Gene_expression of Penk 2 0.46 0.66 0.75
61 INT44502 Regulation of Mt1a Positive_regulation of Prl 1 0.14 0 0.74
62 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
63 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73
64 INT45946 Nts Negative_regulation of Prl 2 0.50 0 0.71
65 INT9290 Pomc Regulation of Prl 2 0.09 0.69 0.71
66 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
67 INT12711 POMC Regulation of Prl 1 0.04 1.25 0.7
68 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
69 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
70 INT46656 Mtr Regulation of Prl 1 0.05 0 0.7
71 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
72 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
73 INT42780 Negative_regulation of Scn4a Negative_regulation of Positive_regulation of Prl 1 0.11 0 0.69
74 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68
75 INT64433 Oxt Negative_regulation of Prl 1 0.05 0 0.68
76 INT31951 Negative_regulation of PIF1 Positive_regulation of Prl 1 0.07 0 0.68
77 INT30503 OPRM1 Regulation of Localization of Prl 1 0.00 0 0.67
78 INT780 Prss12 Positive_regulation of Gene_expression of Prl 1 0.14 0 0.65
79 INT776 Nts Positive_regulation of Gene_expression of Prl 1 0.36 0 0.65
80 INT40662 Pdyn Regulation of Localization of Prl 1 0.18 0 0.64
81 INT774 Nts Positive_regulation of Prl 1 0.34 0 0.64
82 INT13619 Acyp2-ps1 Negative_regulation of Localization of Prl 1 0.13 0 0.63
83 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62
84 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6
85 INT32722 Prl Regulation of Lhb 1 0.02 0 0.6
86 INT5990 Positive_regulation of Oprl1 Positive_regulation of Localization of Prl 1 0.17 0 0.59
87 INT137535 Prl Positive_regulation of Phosphorylation of Trpv1 1 0.56 0.11 0.57
88 INT137534 Prl Positive_regulation of Trpv1 1 0.78 0.11 0.57
89 INT43693 Cyp3a23/3a1 Positive_regulation of Localization of Prl 1 0.10 0 0.57
90 INT45736 Prl Positive_regulation of Gene_expression of Gnrhr 1 0.00 0.1 0.56
91 INT31212 Sst Negative_regulation of Localization of Prl 1 0.20 0 0.55
92 INT31948 Spic Regulation of Localization of Prl 1 0.02 0 0.55
93 INT23840 LH Regulation of Gene_expression of Prl 2 0.24 0.24 0.54
94 INT55206 Prl Negative_regulation of Gnrhr 1 0.37 0 0.54
95 INT46434 Prss12 Negative_regulation of Prl 1 0.16 0 0.54
96 INT45425 Npepo Regulation of Prl 2 0.32 0.16 0.53
97 INT139751 Dbh Regulation of Localization of Prl 1 0.02 0 0.52
98 INT55208 Prl Negative_regulation of Localization of Crh 1 0.43 0 0.51
99 INT55203 Prl Negative_regulation of Localization of Gnrhr 1 0.37 0 0.51
100 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
101 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
102 INT55207 Prl Positive_regulation of Localization of Pomc 1 0.07 0 0.5
103 INT34980 Regulation of Trh Positive_regulation of Localization of Prl 1 0.50 0 0.49
104 INT9291 Regulation of Pomc Regulation of Prl 1 0.05 0.69 0.49
105 INT3435 Positive_regulation of Vip Positive_regulation of Prl 1 0.45 0 0.49
106 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48
107 INT107803 Ugt1a5 Positive_regulation of Prl 2 0.44 0.48 0.48
108 INT55020 Gh1 Regulation of Gene_expression of Prl 1 0.19 0 0.48
109 INT17463 Trh Regulation of Localization of Prl 2 0.30 0.22 0.47
110 INT31844 Grpr Regulation of Localization of Prl 1 0.04 0.37 0.47
111 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
112 INT26338 Binding of OPRM1 and Prl 1 0.02 0.37 0.47
113 INT39181 NPL Regulation of Prl 1 0.16 0 0.47
114 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
115 INT47222 Binding of Gh and Prl 1 0.22 0.18 0.46
116 INT47221 Prl Regulation of Localization of Gh 1 0.28 0.27 0.46
117 INT31952 Localization of PIF1 Regulation of Localization of Prl 1 0.04 0 0.46
118 INT31953 PIF1 Regulation of Localization of Prl 1 0.06 0 0.46
119 INT14374 Zmat3 Positive_regulation of Localization of Prl 1 0.03 0 0.45
120 INT118208 Ghrl Negative_regulation of Localization of Prl 1 0.39 0 0.44
121 INT19906 Positive_regulation of Trh Regulation of Prl 2 0.04 0.47 0.43
122 INT32161 Negative_regulation of Trh Positive_regulation of Prl 1 0.48 0 0.42
123 INT17415 Negative_regulation of TRH Positive_regulation of Prl 1 0.44 0 0.42
124 INT36009 Binding of Drd2 and Prl 1 0.01 1.05 0.42
125 INT76541 Prl Regulation of Localization of Lhb 1 0.12 0 0.41
126 INT55202 Crh Positive_regulation of Negative_regulation of Prl 1 0.51 0 0.41
127 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
128 INT13622 Acyp2-ps1 Regulation of Localization of Prl 1 0.14 0 0.41
129 INT34981 Gene_expression of Dbi Positive_regulation of Localization of Prl 1 0.23 0 0.41
130 INT34979 Gene_expression of Pomc Positive_regulation of Localization of Prl 1 0.09 0 0.41
131 INT20002 GNRH1 Positive_regulation of Gene_expression of Prl 1 0.28 0 0.4
132 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
133 INT44520 PDYN Regulation of Localization of Prl 1 0.00 0 0.4
134 INT36813 Olr824 Positive_regulation of Prl 1 0.05 0 0.39
135 INT36815 Olr824 Regulation of Prl 1 0.03 0 0.39
136 INT18098 PDYN Positive_regulation of Localization of Prl 1 0.00 0 0.37
137 INT4220 Npepo Negative_regulation of Prl 1 0.30 0 0.37
138 INT39484 Gnrh1 Negative_regulation of Localization of Prl 1 0.25 0 0.36
139 INT13617 Acyp2-ps1 Regulation of Prl 1 0.14 0 0.36
140 INT35981 Adrb1 Regulation of Localization of Prl 1 0.00 0 0.36
141 INT12710 Gnrhr Regulation of Prl 1 0.00 0.63 0.35
142 INT20467 Lmo7 Positive_regulation of Localization of Prl 1 0.05 0 0.34
143 INT4222 Prl Negative_regulation of Pif 1 0.04 0 0.34
144 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
145 INT4221 Prl Negative_regulation of Gtf3a 1 0.05 0 0.34
146 INT31843 Grpr Negative_regulation of Localization of Prl 1 0.03 0.34 0.34
147 INT107804 Ugt1a5 Positive_regulation of Ugt1a5 Positive_regulation of Prl 1 0.43 0.19 0.33
148 INT54344 Oprk1 Regulation of Prl 1 0.22 0 0.33
149 INT118210 Ghrl Negative_regulation of Prl 1 0.53 0 0.33
150 INT20468 Ran Negative_regulation of Localization of Prl 1 0.30 0 0.33
151 INT292014 Efs Regulation of Localization of Prl 1 0.26 0 0.33
152 INT140493 GH1 Regulation of Prl 1 0.18 0.47 0.33
153 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
154 INT107802 Ugt1a5 Regulation of Localization of Prl 1 0.29 0.19 0.32
155 INT55201 Prl Regulation of Positive_regulation of Penk 1 0.48 0 0.32
156 INT936 Spic Positive_regulation of Localization of Prl 1 0.09 0 0.31
157 INT3178 TSHR Positive_regulation of Prl 1 0.00 0.58 0.31
158 INT3728 Abat Positive_regulation of Positive_regulation of Prl 1 0.15 0 0.31
159 INT39598 pcp Negative_regulation of Prl 1 0.18 0 0.31
160 INT19512 Prl Positive_regulation of Odc1 1 0.01 0.89 0.31
161 INT29984 Bad Positive_regulation of Localization of Prl 1 0.15 0 0.3
162 INT72950 L1cam Negative_regulation of Localization of Prl 1 0.16 0 0.3
163 INT73053 Prl Positive_regulation of Trh 1 0.22 0 0.3
164 INT222464 Col4a2 Regulation of Localization of Prl 1 0.03 0.32 0.3
165 INT46432 Prl Negative_regulation of Prss12 1 0.16 0 0.3
166 INT45194 Prl3d1 Regulation of Prl 1 0.08 0 0.29
167 INT45422 Npepo Regulation of Localization of Prl 1 0.32 0 0.29
168 INT45195 Prl3d1 Negative_regulation of Prl 1 0.14 0 0.29
169 INT5934 Prl Regulation of Oprm1 1 0.19 0.51 0.28
170 INT88582 Negative_regulation of Hal Positive_regulation of Prl 1 0.12 0.15 0.27
171 INT45751 LH Regulation of Prl 1 0.17 0.24 0.27
172 INT19513 Prl Positive_regulation of IL2 1 0.41 0.8 0.27
173 INT39299 Binding of Prl and Dlst 1 0.20 0 0.27
174 INT64835 Binding of Lhb and Prl 1 0.08 0 0.27
175 INT137536 Prl Regulation of Trpv1 1 0.50 0.19 0.27
176 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
177 INT45196 Cubn Negative_regulation of Prl 1 0.05 0 0.27
178 INT85791 Prlh Regulation of Localization of Prl 1 0.23 0 0.26
179 INT88584 Hal Positive_regulation of Hal Positive_regulation of Prl 1 0.04 0.15 0.26
180 INT222467 Gh1 Positive_regulation of Prl 1 0.04 0.52 0.26
181 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25
182 INT47639 GH1 Positive_regulation of Prl 1 0.09 0.64 0.25
183 INT67992 Binding of Prl and Oprl1 1 0.33 0.16 0.24
184 INT38877 Trhr Positive_regulation of Localization of Prl 1 0.09 0.08 0.24
185 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
186 INT85792 Prlh Positive_regulation of Localization of Prl 1 0.39 0 0.24
187 INT118211 Ghrl Positive_regulation of Localization of Prl 1 0.63 0 0.24
188 INT43713 ENG Regulation of Prl 1 0.00 0 0.23
189 INT164 Ddc Negative_regulation of Prl 1 0.06 0 0.23
190 INT40449 Cck Regulation of Localization of Prl 1 0.49 0 0.23
191 INT49697 ST8SIA4 Regulation of Prl 1 0.01 0.26 0.23
192 INT49693 ST8SIA4 Positive_regulation of ST8SIA4 Regulation of Prl 1 0.00 0.26 0.23
193 INT49686 Sms Negative_regulation of ST8SIA4 Regulation of Prl 1 0.00 0.27 0.23
194 INT49682 Positive_regulation of Trh Positive_regulation of Prl 1 0.05 0.26 0.23
195 INT49699 Sms Negative_regulation of Trh Positive_regulation of Prl 1 0.01 0.27 0.23
196 INT49685 ST8SIA4 Regulation of Trh Positive_regulation of Prl 1 0.00 0.26 0.23
197 INT49694 ST8SIA4 Positive_regulation of Prl 1 0.01 0.26 0.23
198 INT63703 Regulation of TRH Positive_regulation of Prl 1 0.07 0 0.23
199 INT49698 Trh Regulation of Trh Positive_regulation of Prl 1 0.01 0.26 0.23
200 INT49684 Trh Positive_regulation of ST8SIA4 Regulation of Prl 1 0.01 0.26 0.23

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24683. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24683. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 2431 0.81 378.96 952.2
2 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82
3 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78
4 INT162 Regulation of Prl 794 0.62 165.01 322.24
5 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66
6 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24
7 INT528 Gene_expression of Prl 693 0.78 217.18 192.2
8 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8
9 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88
10 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06
11 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36
12 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39
13 INT1512 Binding of Prl 73 0.48 26.22 20.63
14 INT160 Regulation of Positive_regulation of Prl 37 0.62 7.56 20.09
15 INT1975 Regulation of Regulation of Prl 32 0.59 5.78 18.53
16 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79
17 INT1378 Negative_regulation of Regulation of Prl 27 0.43 9.16 9.9
18 INT2059 Positive_regulation of Negative_regulation of Prl 24 0.70 5.7 9.37
19 INT4563 Positive_regulation of Regulation of Prl 20 0.70 4.2 8.1
20 INT3230 Negative_regulation of Negative_regulation of Prl 9 0.43 1.85 4.41
21 INT25500 Regulation of Negative_regulation of Prl 9 0.54 1.19 3.53
22 INT20176 Transcription of Prl 15 0.72 7.32 2.25
23 INT1511 Negative_regulation of Binding of Prl 7 0.59 1.64 2.19
24 INT1513 Regulation of Binding of Prl 4 0.45 0 0.81
25 INT3132 Phosphorylation of Prl 3 0.66 0.48 0.79
26 INT2842 Positive_regulation of Binding of Prl 3 0.50 0 0.59
27 INT86531 Regulation of Transcription of Prl 2 0.44 1.48 0.59
28 INT44322 Protein_catabolism of Prl 2 0.65 1.33 0.39
29 INT20174 Positive_regulation of Transcription of Prl 2 0.69 0.63 0.14
30 INT42169 Negative_regulation of Transcription of Prl 1 0.36 0.91 0
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