G:24954

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Official Symbol Insr
Aliases none
EntrezGene 24954
UniProt Coming Soon
Unique Molecular Interactions 25
Total Molecular Interactions 46
Total Single Events 682
Unique Interaction Partners 21

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Insr. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Insr. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Insr. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
2 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
3 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
4 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
5 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
6 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
7 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
8 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
9 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
10 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
11 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
12 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
13 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
14 INT41406 Binding of Insr and Thtpa 1 0.05 0 0.25
15 INT89158 Grpr Positive_regulation of Localization of Insr 1 0.02 0 0.23
16 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08
17 INT115258 Insr Positive_regulation of Phosphorylation of Irs1 1 0.19 0.26 0.08
18 INT17920 Penk Positive_regulation of Insr 1 0.05 0.14 0.06
19 INT325060 Binding of Insr and Hand1 1 0.00 0.16 0.05
20 INT342170 Insr Regulation of Localization of Cd320 1 0.08 0.92 0.04
21 INT144761 Binding of INSR and Insr 1 0.05 0 0
22 INT144754 Negative_regulation of Binding of Insr and Slc2a2 1 0.01 0 0
23 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
24 INT144753 Binding of Insr and Slc2a2 1 0.01 0 0
25 INT144762 Negative_regulation of Binding of INSR and Insr 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 24954. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 24954. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
2 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
3 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
4 INT8691 Localization of Insr 85 0.80 9.27 30.32
5 INT5300 Regulation of Insr 54 0.60 11.33 29.26
6 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
7 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
8 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
9 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
10 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
11 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
12 INT51084 Binding of Insr 13 0.30 4.25 4.23
13 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
14 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
15 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
16 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
17 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
18 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
19 INT41911 Regulation of Positive_regulation of Insr 2 0.21 0.32 0.88
20 INT91908 Regulation of Negative_regulation of Insr 1 0.03 0.81 0.86
21 INT18445 Regulation of Transcription of Insr 1 0.12 0.84 0.63
22 INT18446 Transcription of Insr 2 0.18 0.84 0.62
23 INT115253 Negative_regulation of Phosphorylation of Insr 1 0.27 0.56 0.25
24 INT92634 Negative_regulation of Binding of Insr 1 0.25 0.08 0.12
25 INT230481 Positive_regulation of Regulation of Insr 1 0.01 0.24 0
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