G:25125

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Official Symbol Stat3
Aliases MGC93551
EntrezGene 25125
UniProt Coming Soon
Unique Molecular Interactions 32
Total Molecular Interactions 41
Total Single Events 230
Unique Interaction Partners 23

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Stat3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Stat3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Stat3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
2 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
3 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
4 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
5 INT328818 Regulation of Il6 Positive_regulation of Stat3 1 0.04 0 0.38
6 INT328825 Il6 Positive_regulation of Stat3 1 0.07 0 0.37
7 INT356274 Egf Positive_regulation of Localization of Stat3 1 0.13 0.22 0.36
8 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
9 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
10 INT155064 Stat3 Negative_regulation of Tp53bp2 1 0.06 3.69 0.33
11 INT155058 Stat3 Negative_regulation of Akp3 1 0.01 3.7 0.33
12 INT298348 ANGPT2 Positive_regulation of Phosphorylation of Stat3 1 0.18 0.14 0.28
13 INT237748 Negative_regulation of Jak3 Negative_regulation of Positive_regulation of Stat3 1 0.25 1.01 0.22
14 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
15 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
16 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
17 INT155067 Csf2 Positive_regulation of Transcription of Stat3 1 0.36 1.45 0.18
18 INT107884 Stat3 Positive_regulation of JUN 1 0.08 0 0.17
19 INT356285 Binding of Stat3 and Egf 1 0.09 0.4 0.13
20 INT299553 GOPC Positive_regulation of Stat3 1 0.02 0 0.13
21 INT275171 Binding of Stat3 and Rac1 Positive_regulation of Rac1 Positive_regulation of Stat3 1 0.01 0.73 0.1
22 INT275157 Binding of Stat3 and Rac1 1 0.05 0.71 0.1
23 INT107883 Stat3 Positive_regulation of Gene_expression of JUN 1 0.08 0 0.1
24 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1
25 INT208298 IGIP Positive_regulation of Stat3 1 0.09 0.48 0.09
26 INT310564 Positive_regulation of Ephb1 Regulation of Stat3 1 0.03 0.17 0.08
27 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
28 INT107886 Stat3 Positive_regulation of Gene_expression of TRPC6 1 0.38 0 0.07
29 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
30 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
31 INT289606 Sirt1 Negative_regulation of Stat3 Positive_regulation of Stat3 1 0.28 0.31 0.03
32 INT275752 xn Positive_regulation of Phosphorylation of Stat3 1 0.04 0.58 0
33 INT275763 STAT3 Regulation of Phosphorylation of Stat3 1 0.31 0 0
34 INT275745 xn Negative_regulation of Positive_regulation of Stat3 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 25125. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 25125. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
2 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
3 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28
4 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06
5 INT97393 Localization of Stat3 11 0.75 7.33 3.01
6 INT129917 Negative_regulation of Phosphorylation of Stat3 6 0.41 0.85 2.51
7 INT140993 Negative_regulation of Positive_regulation of Stat3 6 0.38 3.39 2.39
8 INT140991 Negative_regulation of Stat3 15 0.53 7.55 2.04
9 INT97394 Regulation of Stat3 6 0.41 2.52 1.34
10 INT136470 Positive_regulation of Positive_regulation of Stat3 3 0.40 0.75 1.23
11 INT142068 Positive_regulation of Localization of Stat3 3 0.47 1.6 1.07
12 INT155053 Transcription of Stat3 6 0.50 3.97 1
13 INT155054 Regulation of Gene_expression of Stat3 2 0.50 4.73 0.32
14 INT179341 Binding of Stat3 3 0.23 0.95 0.27
15 INT289579 Negative_regulation of Gene_expression of Stat3 2 0.28 1.01 0.27
16 INT292967 Positive_regulation of Gene_expression of Stat3 4 0.48 1.35 0.06
17 INT356269 Negative_regulation of Localization of Stat3 1 0.15 0 0.05
18 INT275740 Regulation of Phosphorylation of Stat3 2 0.18 0.13 0.04
19 INT289552 Regulation of Localization of Stat3 1 0.29 0.25 0.03
20 INT275742 Regulation of Positive_regulation of Stat3 1 0.28 0 0
21 INT292961 Positive_regulation of Transcription of Stat3 1 0.48 1.4 0
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