G:25402

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Official Symbol Casp3
Aliases Lice, MGC93645
EntrezGene 25402
UniProt Coming Soon
Unique Molecular Interactions 58
Total Molecular Interactions 74
Total Single Events 1482
Unique Interaction Partners 40

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Casp3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Casp3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Casp3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
2 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
3 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
4 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
5 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
6 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
7 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
8 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
9 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
10 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
11 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
12 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
13 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
14 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
15 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
16 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
17 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
18 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
19 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
20 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
21 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
22 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
23 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
24 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
25 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
26 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
27 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
28 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
29 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
30 INT121616 Casp3 Regulation of Enc1 Regulation of Cfp 1 0.00 0 0.47
31 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
32 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
33 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
34 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
35 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
36 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22
37 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
38 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
39 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
40 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
41 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
42 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
43 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
44 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
45 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
46 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
47 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
48 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
49 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
50 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
51 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
52 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
53 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
54 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
55 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
56 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
57 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
58 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0
59 INT229809 Fos Regulation of Casp3 1 0.06 0.32 0
60 INT242159 Wnt2 Positive_regulation of Localization of Casp3 1 0.05 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 25402. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 25402. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
3 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
4 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
5 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
6 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
7 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
8 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
9 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
10 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
11 INT98178 Localization of Casp3 32 0.65 21.01 7.77
12 INT57232 Binding of Casp3 22 0.36 9.42 6.2
13 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
14 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
15 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
16 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
17 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
18 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
19 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
20 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
21 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
22 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
23 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
24 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
25 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
26 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44
27 INT141820 Positive_regulation of Binding of Casp3 1 0.12 0.55 0.24
28 INT195018 Regulation of Negative_regulation of Casp3 1 0.21 0.48 0.2
29 INT171688 Positive_regulation of Transcription of Casp3 3 0.28 1.16 0.08
30 INT237443 Positive_regulation of Phosphorylation of Casp3 1 0.39 0.09 0
31 INT242155 Negative_regulation of Localization of Casp3 1 0.04 0.25 0
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