G:25496

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Official Symbol Notch1
Aliases TAN1, NOTCH
EntrezGene 25496
UniProt Coming Soon
Unique Molecular Interactions 18
Total Molecular Interactions 20
Total Single Events 105
Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Notch1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Notch1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Notch1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
3 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
4 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
5 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
6 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
7 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
8 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
9 INT264697 Binding of Hes1 and Mir199b Regulation of Notch1 1 0.00 0.86 0
10 INT356083 Binding of App and Notch1 1 0.02 0.2 0
11 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
12 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
13 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
14 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
15 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
16 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
17 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
18 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
19 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 25496. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 25496. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
2 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
3 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
4 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
5 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
6 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
7 INT110780 Localization of Notch1 2 0.06 0.47 1.19
8 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
9 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
10 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
11 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
12 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
13 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
14 INT193945 Binding of Notch1 7 0.15 1.28 0.19
15 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
16 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
17 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0
18 INT273836 Positive_regulation of Regulation of Notch1 1 0.15 0.05 0
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