G:25569

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Official Symbol Trh
Aliases THR, TRH01
EntrezGene 25569
UniProt Coming Soon
Unique Molecular Interactions 112
Total Molecular Interactions 206
Total Single Events 1415
Unique Interaction Partners 50

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Trh. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Trh. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Trh. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
2 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
3 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
4 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05
5 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
6 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
7 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
8 INT32839 Binding of Trh and Penk 2 0.42 0 1.63
9 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
10 INT7927 Penk Regulation of Trh 2 0.26 0.66 1.09
11 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05
12 INT32840 Regulation of Binding of Trh and Penk 1 0.26 0 0.91
13 INT52557 Lhb Regulation of Trh Positive_regulation of Prl 1 0.00 0.14 0.83
14 INT52558 Lhb Regulation of Trh Regulation of Prl 1 0.00 0.14 0.83
15 INT52573 Trh Regulation of Trh Regulation of Prl 1 0.00 0.14 0.82
16 INT7926 Regulation of Penk Regulation of Trh 1 0.26 0.66 0.8
17 INT52561 Trh Positive_regulation of Localization of Lhb 1 0.01 0.14 0.77
18 INT3570 Trh Regulation of Localization of Gnrhr 2 0.26 0.3 0.75
19 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
20 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
21 INT41920 Tacr1 Negative_regulation of Binding of Tacr1 and Trh 1 0.01 0 0.74
22 INT43717 Positive_regulation of Binding of Trh and Penk 1 0.56 0 0.72
23 INT40763 Trh Negative_regulation of Penk 1 0.19 0 0.65
24 INT107330 Binding of Adarb1 and Trh 1 0.01 0 0.65
25 INT40762 Trh Negative_regulation of Prss12 1 0.06 0 0.65
26 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
27 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62
28 INT40153 Gnrh1 Regulation of Trh 1 0.47 0 0.59
29 INT10079 Cp Regulation of Trh 1 0.01 0.59 0.53
30 INT49696 Trh Regulation of GH1 2 0.02 0.22 0.52
31 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51
32 INT34980 Regulation of Trh Positive_regulation of Localization of Prl 1 0.50 0 0.49
33 INT17610 Binding of Ctse and Trh 1 0.27 0.89 0.49
34 INT30801 Penk Negative_regulation of Trh 1 0.09 0 0.49
35 INT61510 Binding of Trh and Gm14673 1 0.01 0 0.48
36 INT30802 Pomc Negative_regulation of Trh 1 0.11 0 0.48
37 INT17463 Trh Regulation of Localization of Prl 2 0.30 0.22 0.47
38 INT34982 Trh Regulation of Dbi 1 0.12 0 0.47
39 INT34984 Negative_regulation of Trh Regulation of Dbi 1 0.19 0 0.47
40 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
41 INT19906 Positive_regulation of Trh Regulation of Prl 2 0.04 0.47 0.43
42 INT32161 Negative_regulation of Trh Positive_regulation of Prl 1 0.48 0 0.42
43 INT34985 Gene_expression of Pomc Positive_regulation of Localization of Trh 1 0.09 0 0.42
44 INT34983 Gene_expression of Dbi Positive_regulation of Localization of Trh 1 0.22 0 0.42
45 INT44312 Binding of Trh and Pag1 1 0.05 0.36 0.41
46 INT196797 Trh Negative_regulation of Prkaca 1 0.01 0 0.41
47 INT35201 Trh Regulation of Tshb 1 0.01 0.28 0.39
48 INT33713 Binding of ITPR3 and Trh 1 0.00 0.86 0.39
49 INT196800 Trh Negative_regulation of Ppp1cc 1 0.01 0 0.39
50 INT196796 Ppp1r1b Negative_regulation of Phosphorylation of Trh 1 0.01 0 0.39
51 INT3634 Trh Regulation of Gh1 3 0.20 0.23 0.38
52 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36
53 INT29118 Trh Regulation of Oprd1 1 0.24 0.79 0.31
54 INT196798 Trh Positive_regulation of Phosphorylation of Ppp1r1b 1 0.01 0 0.3
55 INT73053 Prl Positive_regulation of Trh 1 0.22 0 0.3
56 INT222529 Binding of Trh and Vip 1 0.07 0.09 0.29
57 INT3638 Trh Regulation of Localization of Gnrh1 1 0.17 0 0.29
58 INT40151 Nts Regulation of Trh 1 0.21 0 0.29
59 INT40152 Sst Regulation of Trh 1 0.22 0 0.29
60 INT41192 Trh Positive_regulation of Localization of POMC 1 0.04 0 0.29
61 INT25375 Trh Regulation of Gh 1 0.04 1.01 0.28
62 INT17351 Npy Regulation of Trh 1 0.46 0 0.28
63 INT3569 Trh Negative_regulation of Positive_regulation of Gh1 1 0.20 0 0.27
64 INT3574 Trh Negative_regulation of Localization of Gh1 1 0.15 0 0.27
65 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
66 INT122232 Trh Positive_regulation of Positive_regulation of LH 1 0.18 0 0.24
67 INT122225 Trh Positive_regulation of Gh1 1 0.06 0 0.24
68 INT122222 Trh Positive_regulation of LH 1 0.18 0 0.24
69 INT49682 Positive_regulation of Trh Positive_regulation of Prl 1 0.05 0.26 0.23
70 INT49699 Sms Negative_regulation of Trh Positive_regulation of Prl 1 0.01 0.27 0.23
71 INT49685 ST8SIA4 Regulation of Trh Positive_regulation of Prl 1 0.00 0.26 0.23
72 INT49698 Trh Regulation of Trh Positive_regulation of Prl 1 0.01 0.26 0.23
73 INT49684 Trh Positive_regulation of ST8SIA4 Regulation of Prl 1 0.01 0.26 0.23
74 INT19905 Trh Regulation of Gnrhr 1 0.00 0.25 0.22
75 INT33714 Positive_regulation of Binding of ITPR3 and Trh 1 0.00 0.46 0.21
76 INT53230 Trh Positive_regulation of Tshb 1 0.55 0.2 0.2
77 INT3635 Trh Regulation of Localization of Tshb 1 0.35 0.3 0.19
78 INT122236 Gnrh1 Positive_regulation of Trh 1 0.29 0 0.19
79 INT3619 Trh Positive_regulation of Localization of Gnrhr 2 0.48 0.2 0.18
80 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18
81 INT60348 Trh Positive_regulation of Positive_regulation of Acot1 1 0.29 0.44 0.17
82 INT10291 Trh Regulation of CTSC 1 0.01 0 0.16
83 INT32286 POMC Negative_regulation of Trh 1 0.01 0 0.15
84 INT74070 Trh Regulation of Lhb 1 0.02 0.27 0.15
85 INT32285 POMC Regulation of Trh 1 0.01 0 0.15
86 INT32287 POMC Regulation of Localization of Trh 1 0.03 0 0.15
87 INT44393 Vip Positive_regulation of Localization of Trh 1 0.51 0 0.14
88 INT32294 ENG Positive_regulation of Trh 1 0.01 0 0.13
89 INT34443 Negative_regulation of Binding of Trh and Ptprg 1 0.20 0.08 0.12
90 INT34445 Binding of Trh and Ptprg 1 0.23 0.08 0.12
91 INT33323 Regulation of Trh Positive_regulation of Prl 1 0.30 0 0.1
92 INT3562 Trh Positive_regulation of Klkb1 1 0.10 0 0.1
93 INT34932 NA Positive_regulation of Localization of Trh 1 0.01 0 0.1
94 INT33712 Trh Positive_regulation of Localization of ITPR3 1 0.00 0.8 0.1
95 INT27051 Trhde Regulation of Negative_regulation of Trh 1 0.17 0 0.09
96 INT32288 POMC Regulation of Positive_regulation of Trh 1 0.03 0 0.09
97 INT222483 Trh Regulation of Gene_expression of Gh1 1 0.03 0 0.09
98 INT218733 Trh Positive_regulation of Gene_expression of Hdc 1 0.27 0 0.09
99 INT32290 ENG Regulation of Positive_regulation of Trh 1 0.01 0 0.09
100 INT1387 Binding of Gnrh1 and Trh 1 0.29 0 0.08
101 INT33324 Regulation of Binding of Prl and Trh 1 0.50 0 0.08
102 INT33325 Binding of Prl and Trh 1 0.42 0 0.08
103 INT1389 Binding of LH and Trh 1 0.16 0 0.08
104 INT1386 Negative_regulation of Binding of and Trh 1 0.18 0 0.08
105 INT1391 Negative_regulation of Binding of Gnrh1 and Trh 1 0.34 0 0.08
106 INT34448 Trh Negative_regulation of Negative_regulation of Ptprg 1 0.23 0 0.07
107 INT34450 Pck1 Regulation of Binding of Trh 1 0.15 0 0.07
108 INT53228 Negative_regulation of Trh Positive_regulation of Tshb 1 0.47 0.06 0.06
109 INT3620 Trh Positive_regulation of Positive_regulation of Gh1 1 0.49 0 0.06
110 INT17919 Trh Positive_regulation of Fos 1 0.40 0.14 0.06
111 INT53231 Trh Positive_regulation of Trh Positive_regulation of Tshb 1 0.30 0.06 0.06
112 INT222487 Trh Negative_regulation of Nmb 1 0.05 0.26 0.05
113 INT53229 Trh Regulation of Gene_expression of Tshb 1 0.49 0.05 0.05
114 INT217590 Binding of Trh and Trhr2 1 0.04 0 0.04
115 INT321294 Ins1 Positive_regulation of Trh 1 0.00 0.08 0.04
116 INT273117 Trh Positive_regulation of Rps6kb1 1 0.01 0.09 0.04
117 INT222562 Trh Regulation of Localization of LH 1 0.04 0 0.03
118 INT222468 Nmb Positive_regulation of Localization of Trh 1 0.05 0.28 0.03
119 INT222510 Nmb Positive_regulation of Trh 1 0.05 0.28 0.03
120 INT218731 Lep Positive_regulation of Gene_expression of Trh 1 0.19 0.07 0
121 INT222496 Trh Positive_regulation of Gene_expression of Prl 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 25569. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 25569. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT339 Regulation of Trh 156 0.62 39.27 83.55
2 INT403 Localization of Trh 241 0.81 28.55 81.45
3 INT1376 Binding of Trh 121 0.48 20 69.86
4 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
5 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5
6 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63
7 INT61665 Phosphorylation of Trh 53 0.79 2.26 23.9
8 INT1327 Regulation of Localization of Trh 45 0.62 6.05 22.09
9 INT14419 Negative_regulation of Localization of Trh 40 0.59 2.04 17.42
10 INT13209 Regulation of Binding of Trh 19 0.62 2.84 16.26
11 INT23825 Negative_regulation of Binding of Trh 17 0.59 1.62 11.24
12 INT3637 Positive_regulation of Localization of Trh 33 0.70 2.13 10.55
13 INT143964 Positive_regulation of Phosphorylation of Trh 10 0.20 0.1 10.54
14 INT9932 Positive_regulation of Positive_regulation of Trh 13 0.50 1.8 7.63
15 INT7923 Transcription of Trh 14 0.72 4.44 6.32
16 INT34440 Negative_regulation of Positive_regulation of Trh 12 0.59 0 5.7
17 INT10078 Positive_regulation of Gene_expression of Trh 17 0.50 4.23 5.19
18 INT5015 Regulation of Gene_expression of Trh 9 0.62 6.47 4.25
19 INT2324 Positive_regulation of Regulation of Trh 7 0.50 2.22 2.65
20 INT59531 Positive_regulation of Transcription of Trh 6 0.69 1.31 2.42
21 INT988 Positive_regulation of Negative_regulation of Trh 3 0.50 0 2.39
22 INT16285 Regulation of Negative_regulation of Trh 3 0.62 0.9 2.22
23 INT133703 Negative_regulation of Phosphorylation of Trh 4 0.19 0.85 1.88
24 INT25332 Positive_regulation of Binding of Trh 3 0.50 0.08 1.84
25 INT16284 Negative_regulation of Negative_regulation of Trh 5 0.43 0.39 1.75
26 INT19999 Regulation of Positive_regulation of Trh 5 0.44 0.15 1.26
27 INT17918 Regulation of Regulation of Trh 4 0.45 1.37 1.11
28 INT13808 Negative_regulation of Regulation of Trh 3 0.43 0.18 1
29 INT89109 Regulation of Transcription of Trh 2 0.45 1.98 0.74
30 INT59532 Negative_regulation of Transcription of Trh 2 0.18 0.4 0.59
31 INT196794 Regulation of Phosphorylation of Trh 1 0.04 0 0.51
32 INT27047 Protein_catabolism of Trh 5 0.91 0.06 0.26
33 INT70640 Positive_regulation of Protein_catabolism of Trh 1 0.34 0.06 0.03
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