G:260431

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Official Symbol COPD
Aliases none
EntrezGene 260431
UniProt Coming Soon
Unique Molecular Interactions 40
Total Molecular Interactions 52
Total Single Events 820
Unique Interaction Partners 32

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to COPD. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to COPD. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to COPD. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
2 INT219685 Binding of MMP12 and COPD 1 0.27 5.59 0.74
3 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4
4 INT261597 Binding of PAH and COPD 1 0.00 1.08 0.34
5 INT335446 Binding of PDX1 and COPD 1 0.02 1.99 0.3
6 INT275555 Binding of Ltb4r1 and COPD 1 0.01 1.02 0.3
7 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29
8 INT272930 Positive_regulation of Binding of Mmp1a and COPD 1 0.01 0.79 0.29
9 INT272933 Binding of Mmp1a and COPD 1 0.01 0.78 0.29
10 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29
11 INT272928 Positive_regulation of Binding of Mmp12 and COPD 1 0.01 0.79 0.29
12 INT335447 PDX1 Regulation of Gene_expression of COPD 1 0.02 1.03 0.24
13 INT310939 Binding of ELANE and COPD 1 0.08 1.51 0.2
14 INT259634 Elane Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17
15 INT259633 Mmp9 Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17
16 INT310937 Binding of CD8A and COPD 1 0.16 1.21 0.16
17 INT263180 Binding of PDE5A and COPD 1 0.01 1 0.15
18 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15
19 INT263178 Binding of PDE7A and COPD 1 0.01 1 0.15
20 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15
21 INT263174 PDE7A Regulation of COPD 1 0.01 1 0.15
22 INT263176 Binding of PDE4A and COPD 1 0.01 1 0.15
23 INT263175 PDE5A Regulation of COPD 1 0.00 1 0.15
24 INT269013 Binding of CSRP1 and COPD 1 0.08 1.3 0.11
25 INT259636 Binding of Tbce and COPD 1 0.04 1 0.11
26 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
27 INT337536 Binding of Klrk1 and COPD 1 0.03 3.09 0.09
28 INT263100 Binding of EFS and COPD 1 0.14 4.14 0.07
29 INT315996 Binding of HMI and COPD 1 0.01 1.34 0.05
30 INT259638 COPD Positive_regulation of NFE2L2 1 0.03 1.31 0.05
31 INT224150 Binding of TREM1 and COPD 1 0.07 0.7 0.05
32 INT272867 Binding of NLRP1 and COPD 1 0.00 1.07 0
33 INT191900 Binding of EXOSC10 and COPD 1 0.01 0.53 0
34 INT221910 Binding of SRI and COPD 1 0.01 1.27 0
35 INT233401 COPD Regulation of HEY1 1 0.07 1.67 0
36 INT269014 Binding of EGR1 and COPD 1 0.12 0.96 0
37 INT233400 COPD Regulation of CRH 1 0.11 1.67 0
38 INT193204 Binding of TMED4 and COPD 1 0.02 0.29 0
39 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0
40 INT273197 Binding of BCR and COPD 1 0.03 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 260431. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 260431. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1
2 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27
3 INT70970 Binding of COPD 144 0.42 180.34 18.29
4 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08
5 INT150867 Regulation of COPD 54 0.48 71.38 8.8
6 INT147793 Localization of COPD 70 0.64 89.01 7.3
7 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42
8 INT179686 Regulation of Gene_expression of COPD 10 0.34 14.1 1.52
9 INT179688 Negative_regulation of Gene_expression of COPD 13 0.35 16.06 0.97
10 INT221384 Positive_regulation of Localization of COPD 6 0.29 9.13 0.75
11 INT310949 Regulation of Positive_regulation of COPD 1 0.32 1.59 0.5
12 INT272921 Regulation of Localization of COPD 1 0.19 2.82 0.43
13 INT272917 Positive_regulation of Negative_regulation of COPD 1 0.05 0.93 0.42
14 INT259578 Negative_regulation of Positive_regulation of COPD 1 0.26 1.76 0.41
15 INT259664 Positive_regulation of Positive_regulation of COPD 3 0.36 4.81 0.37
16 INT263095 Transcription of COPD 3 0.53 2.78 0.33
17 INT275343 Positive_regulation of Binding of COPD 2 0.42 3.04 0.33
18 INT179684 Protein_catabolism of COPD 4 0.25 4.25 0.27
19 INT270441 Negative_regulation of Negative_regulation of COPD 3 0.36 4.18 0.23
20 INT263203 Negative_regulation of Localization of COPD 3 0.36 4.09 0.22
21 INT272057 Phosphorylation of COPD 2 0.54 4.15 0.22
22 INT259580 Negative_regulation of Binding of COPD 2 0.10 3.44 0.17
23 INT325353 Regulation of Binding of COPD 1 0.25 0.56 0.13
24 INT275603 Regulation of Negative_regulation of COPD 1 0.03 0.88 0
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