G:26395

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Official Symbol Map2k1
Aliases Mek1, MEKK1, MAPKK1, Prkmk1
EntrezGene 26395
UniProt Coming Soon
Unique Molecular Interactions 19
Total Molecular Interactions 24
Total Single Events 247
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Map2k1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Map2k1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Map2k1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
2 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
3 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
4 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
5 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
6 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18
7 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
8 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03
9 INT269504 Lta Negative_regulation of Map2k1 Negative_regulation of Nos1 1 0.17 0.49 0.03
10 INT254689 Gene_expression of Map2k2 Positive_regulation of Map2k1 1 0.30 0.4 0
11 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
12 INT254692 Positive_regulation of Map2k1 Regulation of Gene_expression of Mdk 1 0.05 0.42 0
13 INT236937 Map2k1 Negative_regulation of Ppara Positive_regulation of Itk 1 0.00 0.31 0
14 INT254693 Gene_expression of Map2k1 Regulation of Map2k2 1 0.29 0.78 0
15 INT254686 Gene_expression of Map2k1 Regulation of Gene_expression of Mdk 1 0.08 0.42 0
16 INT254703 Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 0.91 0
17 INT254696 Map2k2 Regulation of Map2k1 1 0.18 0.78 0
18 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
19 INT254704 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 1.43 0
20 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
21 INT254684 Map2k2 Positive_regulation of Map2k1 1 0.45 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 26395. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 26395. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
2 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
3 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
4 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
5 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
6 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
7 INT138282 Positive_regulation of Gene_expression of Map2k1 13 0.49 7.46 0.39
8 INT175506 Regulation of Positive_regulation of Map2k1 2 0.32 1.58 0.23
9 INT254671 Regulation of Map2k1 5 0.43 1.83 0.14
10 INT175527 Localization of Map2k1 4 0.31 2.41 0.13
11 INT254673 Positive_regulation of Positive_regulation of Map2k1 3 0.35 1.65 0.11
12 INT281764 Negative_regulation of Gene_expression of Map2k1 1 0.18 1.11 0.04
13 INT281758 Positive_regulation of Protein_catabolism of Map2k1 1 0.29 0.13 0
14 INT281756 Protein_catabolism of Map2k1 1 0.42 0.13 0
15 INT175533 Regulation of Gene_expression of Map2k1 1 0.20 1.55 0
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