G:26410

From wiki-pain
Jump to: navigation, search
Official Symbol Map3k8
Aliases Cot, Est, Estf, Tpl2, Tpl-2, c-COT, Cot/Tpl2
EntrezGene 26410
UniProt Coming Soon
Unique Molecular Interactions 10
Total Molecular Interactions 11
Total Single Events 144
Unique Interaction Partners 7

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Map3k8. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Map3k8. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Map3k8. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32
2 INT291241 Map3k8 Positive_regulation of Gene_expression of Mapk1 1 0.17 0.72 0.32
3 INT291249 Map3k8 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
4 INT291257 Map3k8 Regulation of Positive_regulation of MAPK1 1 0.09 1 0.28
5 INT291252 Gene_expression of Map3k8 Positive_regulation of MAPK1 1 0.09 0.64 0.14
6 INT291251 Map3k8 Regulation of Gene_expression of MAPK8 1 0.05 0.52 0.11
7 INT291260 Map3k8 Regulation of Gene_expression of MAPK14 1 0.07 0.52 0.11
8 INT291239 Map3k8 Regulation of Positive_regulation of Mdk 1 0.08 0.53 0.11
9 INT332806 Positive_regulation of Ccl20 Regulation of Map3k8 1 0.05 0.05 0.1
10 INT226900 Binding of Mdk and Map3k8 1 0.05 0.14 0
11 INT226908 Binding of Nfkb1 and Map3k8 1 0.14 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 26410. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 26410. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT162365 Gene_expression of Map3k8 33 0.58 22.75 4.95
2 INT162366 Positive_regulation of Map3k8 24 0.50 15.69 3.71
3 INT162368 Negative_regulation of Map3k8 17 0.42 7.96 3.34
4 INT226868 Transcription of Map3k8 2 0.52 17.13 1.73
5 INT291207 Positive_regulation of Transcription of Map3k8 1 0.50 11.36 1.53
6 INT291221 Regulation of Gene_expression of Map3k8 1 0.44 5.59 1
7 INT162367 Regulation of Map3k8 4 0.33 2.09 0.81
8 INT291214 Positive_regulation of Gene_expression of Map3k8 1 0.50 4.2 0.63
9 INT291223 Protein_catabolism of Map3k8 1 0.72 3.22 0.58
10 INT162364 Binding of Map3k8 2 0.35 1.26 0.49
11 INT291212 Positive_regulation of Protein_catabolism of Map3k8 1 0.34 2.86 0.42
12 INT291213 Negative_regulation of Gene_expression of Map3k8 1 0.31 0.97 0.36
13 INT291224 Negative_regulation of Protein_catabolism of Map3k8 1 0.42 1.07 0.33
14 INT202728 Localization of Map3k8 4 0.54 1.19 0.28
15 INT291215 Positive_regulation of Positive_regulation of Map3k8 1 0.36 1.42 0.27
16 INT291228 Positive_regulation of Localization of Map3k8 1 0.36 1.19 0.19
17 INT291211 Negative_regulation of Transcription of Map3k8 1 0.31 0.87 0.18
18 INT291205 Phosphorylation of Map3k8 1 0.59 0.83 0.18
19 INT291206 Negative_regulation of Positive_regulation of Map3k8 1 0.31 0.61 0.15
20 INT332805 Regulation of Regulation of Map3k8 1 0.14 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox