G:26416

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Official Symbol Mapk14
Aliases p38, Crk1, Mxi2, p38a, CSBP2, Csbp1, PRKM14, PRKM15, p38MAPK, p38alpha, MGC102436, p38-alpha
EntrezGene 26416
UniProt Coming Soon
Unique Molecular Interactions 112
Total Molecular Interactions 125
Total Single Events 1056
Unique Interaction Partners 70

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Mapk14. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Mapk14. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Mapk14. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
2 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
3 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
4 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
5 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
6 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
7 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
8 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
9 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
10 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
11 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
12 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
13 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
14 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
15 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82
16 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
17 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
18 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
19 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
20 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
21 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65
22 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65
23 INT166303 Adrbk1 Positive_regulation of Binding of Mapk14 and Gpbar1 1 0.22 0.65 0.65
24 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
25 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61
26 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
27 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61
28 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57
29 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
30 INT110031 Positive_regulation of Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
31 INT110030 Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
32 INT110034 Negative_regulation of Adra2c Positive_regulation of Mapk14 1 0.23 0 0.48
33 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
34 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
35 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
36 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42
37 INT319313 Socs4 Positive_regulation of Mapk14 1 0.02 0.68 0.41
38 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
39 INT152241 Mapk14 Positive_regulation of Localization of Nfkb1 1 0.25 0.13 0.39
40 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
41 INT223874 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Ltp 1 0.13 0 0.34
42 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33
43 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
44 INT288203 Binding of Cd14 and Mapk14 1 0.08 0.63 0.31
45 INT312546 Ros1 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.87 0.25
46 INT327313 Positive_regulation of Mapk14 Positive_regulation of Phosphorylation of Khsrp 1 0.09 0.24 0.22
47 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2
48 INT208942 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of Jun 1 0.10 0.42 0.2
49 INT284446 Dep1 Positive_regulation of Mapk14 1 0.01 0.58 0.18
50 INT327306 Mapk6 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of IL8 1 0.00 0.3 0.16
51 INT228216 Positive_regulation of Mapk14 Regulation of Gene_expression of Tlr2 1 0.09 1.11 0.15
52 INT329985 Positive_regulation of Prkaca Positive_regulation of Positive_regulation of Mapk14 1 0.15 0.87 0.15
53 INT327324 Mapk6 Positive_regulation of Mapk14 1 0.01 0.29 0.15
54 INT327329 S100a8 Positive_regulation of Mapk14 1 0.00 0.36 0.14
55 INT327309 Il1 Positive_regulation of Mapk14 1 0.01 0.36 0.14
56 INT327319 Binding of Mapk14 and Ttpa 1 0.01 0.34 0.14
57 INT272927 Mapk14 Positive_regulation of Gene_expression of TNF 1 0.16 0.53 0.14
58 INT224677 L1cam Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.39 0.13
59 INT327318 Mapk14 Regulation of Localization of Elavl1 1 0.09 0.42 0.13
60 INT327330 Mapk14 Regulation of Il1 1 0.01 0.33 0.12
61 INT308004 Rsph1 Positive_regulation of Mapk14 1 0.02 0.61 0.12
62 INT331797 Ugcg Regulation of Negative_regulation of Mapk14 1 0.01 1.03 0.11
63 INT331794 Binding of Ugcg and Regulation of Negative_regulation of Mapk14 1 0.01 1.05 0.11
64 INT314590 Binding of Ifnar1 and Positive_regulation of Mapk14 1 0.16 0 0.1
65 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 0.29 0.21 0.09
66 INT202402 Binding of Akt1 and Mapk14 1 0.11 0.13 0.09
67 INT260947 Mapk14 Positive_regulation of Aqp3 1 0.29 0.21 0.09
68 INT202406 Binding of Osm and Mapk14 1 0.21 0.13 0.09
69 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 0.29 0.21 0.09
70 INT202399 Binding of Mapk14 and Racgap1 1 0.07 0.13 0.09
71 INT202393 Binding of Mapk14 and Nexn 1 0.03 0.13 0.09
72 INT202401 Binding of Map3k3 and Mapk14 1 0.41 0.13 0.09
73 INT231512 Positive_regulation of Tlr4 Positive_regulation of Mapk14 1 0.06 0.15 0.07
74 INT325275 IL1RAP Positive_regulation of Mapk14 1 0.13 0 0.07
75 INT231513 Tlr4 Positive_regulation of Positive_regulation of Mapk14 1 0.06 0.15 0.07
76 INT288204 Akt1 Regulation of Mapk14 1 0.01 0.09 0.07
77 INT325258 Il1rap Positive_regulation of Mapk14 1 0.08 0 0.07
78 INT308967 Gpr18 Positive_regulation of Mapk14 1 0.06 0.08 0.06
79 INT344345 Mapk14 Regulation of Gene_expression of VEGFA 1 0.01 0.37 0.05
80 INT178430 Pawr Positive_regulation of Phosphorylation of Mapk14 1 0.05 0.29 0.05
81 INT178447 Negative_regulation of Pawr Positive_regulation of Phosphorylation of Mapk14 1 0.05 0.29 0.05
82 INT178443 Negative_regulation of Mapk8 Positive_regulation of Negative_regulation of Mapk14 1 0.13 0.76 0.04
83 INT178436 Mapk14 Positive_regulation of Gene_expression of Hist1h1a 1 0.17 0.2 0.04
84 INT340552 Binding of Mapk1 and Mapk14 1 0.07 0.27 0.03
85 INT213036 Hdl1 Positive_regulation of Phosphorylation of Mapk14 1 0.22 0.78 0.03
86 INT213004 Hdl1 Positive_regulation of Mapk14 1 0.22 0.97 0.03
87 INT336107 Negative_regulation of Prkag1 Negative_regulation of Phosphorylation of Mapk14 1 0.02 0.27 0
88 INT305266 Obsty1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.05 0
89 INT178440 Map2k4 Positive_regulation of Mapk14 1 0.04 0.13 0
90 INT337848 Ros1 Positive_regulation of Gene_expression of Mapk14 1 0.14 0.27 0
91 INT176534 Mapk14 Positive_regulation of Spp1 1 0.14 0.42 0
92 INT202405 Mapk14 Regulation of Binding of Nexn 1 0.04 0.09 0
93 INT202403 Ass1 Positive_regulation of Mapk14 1 0.01 0 0
94 INT300862 Bdnf Positive_regulation of Mapk14 1 0.02 0.11 0
95 INT349174 Mapk14 Positive_regulation of Phosphorylation of Hspb1 1 0.35 0.2 0
96 INT202408 Mapk14 Regulation of Phosphorylation of Mapkapk5 1 0.50 0.2 0
97 INT178433 Fgf1 Positive_regulation of Mapk14 1 0.02 0.65 0
98 INT176553 Pik3r1 Positive_regulation of Positive_regulation of Mapk14 1 0.02 0.41 0
99 INT202396 Mapk14 Regulation of Nexn 1 0.02 0.09 0
100 INT340563 Gopc Regulation of Phosphorylation of Mapk14 1 0.04 0.91 0
101 INT202404 Regulation of Binding of Mapk14 and Ccm2 1 0.30 0.05 0
102 INT240907 Mapk14 Positive_regulation of Creb1 1 0.13 0.34 0
103 INT231511 Negative_regulation of Tlr4 Positive_regulation of Mapk14 1 0.06 0 0
104 INT231506 Regulation of Tlr4 Positive_regulation of Mapk14 1 0.04 0 0
105 INT240895 Mapk14 Regulation of Phosphorylation of Creb1 1 0.12 0.17 0
106 INT347008 Tlr4 Positive_regulation of Phosphorylation of Mapk14 1 0.02 0.06 0
107 INT262703 Mapk14 Positive_regulation of Bace1 1 0.29 0.39 0
108 INT202398 Mapk14 Regulation of Phosphorylation of Mapkapk2 1 0.44 0.1 0
109 INT176556 Binding of Mapk14 and Positive_regulation of Gene_expression of Spp1 1 0.14 0.43 0
110 INT176544 Mapk14 Positive_regulation of Transcription of Spp1 1 0.20 0.42 0
111 INT286729 Positive_regulation of Mapk14 Positive_regulation of Ppargc1a 1 0.44 0.1 0
112 INT336108 Mapk14 Positive_regulation of Gene_expression of Prkag1 1 0.03 0.26 0
113 INT320554 Mapk14 Positive_regulation of MEF2A 1 0.26 1.31 0
114 INT202395 Binding of Mapk14 and Ccm2 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 26416. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 26416. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
2 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
3 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
4 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
5 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
6 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
7 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
8 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
9 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
10 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
11 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21
12 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86
13 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74
14 INT202365 Regulation of Gene_expression of Mapk14 6 0.45 4.89 1.26
15 INT126525 Regulation of Negative_regulation of Mapk14 2 0.41 0.81 1.11
16 INT178391 Localization of Mapk14 9 0.68 5.27 0.97
17 INT231494 Regulation of Phosphorylation of Mapk14 2 0.24 2.59 0.93
18 INT219268 Negative_regulation of Negative_regulation of Mapk14 2 0.38 0.99 0.8
19 INT314190 Negative_regulation of Localization of Mapk14 1 0.36 0.91 0.69
20 INT231499 Positive_regulation of Negative_regulation of Mapk14 3 0.24 1.58 0.43
21 INT207377 Positive_regulation of Regulation of Mapk14 1 0.20 0.67 0.32
22 INT250776 Protein_catabolism of Mapk14 3 0.52 1.04 0.14
23 INT178395 Transcription of Mapk14 6 0.61 0.47 0.07
24 INT178408 Positive_regulation of Localization of Mapk14 2 0.42 0.87 0.04
25 INT288182 Regulation of Transcription of Mapk14 1 0.40 0.33 0.03
26 INT288195 Negative_regulation of Transcription of Mapk14 1 0.08 0.06 0.03
27 INT288187 Positive_regulation of Transcription of Mapk14 1 0.09 0.06 0.03
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