G:29256

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Official Symbol Oprl1
Aliases KOR3, OFQR, ORL1, Oprl, XOR1, KOR-3, LC132, MOR-C
EntrezGene 29256
UniProt Coming Soon
Unique Molecular Interactions 87
Total Molecular Interactions 168
Total Single Events 1313
Unique Interaction Partners 64

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Oprl1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Oprl1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Oprl1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4
2 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57
3 INT34444 Binding of Oprl1 and Ptprg 4 0.03 0.18 4.58
4 INT34534 Binding of Penk and Oprl1 4 0.37 0 3.64
5 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 0.03 0.13 3.64
6 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
7 INT31534 Binding of Sst and Oprl1 2 0.16 0.53 1.74
8 INT79365 Pnoc Negative_regulation of Oprl1 2 0.41 0.16 1.72
9 INT80787 Negative_regulation of Binding of Pnoc and Oprl1 2 0.39 0.39 1.72
10 INT41652 Binding of Pomc and Oprl1 3 0.16 0 1.57
11 INT6768 Oprl1 Regulation of Localization of Prl 2 0.12 0 1.55
12 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
13 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
14 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
15 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
16 INT76508 Pnoc Regulation of Oprl1 1 0.47 0.25 1.32
17 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29
18 INT24378 Penk Regulation of Oprl1 1 0.10 0 1.29
19 INT71070 Positive_regulation of Oprl1 Positive_regulation of Gene_expression of Cck 1 0.26 0 1.24
20 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
21 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
22 INT17601 Binding of POMC and Oprl1 1 0.01 0 1.2
23 INT1619 Binding of Gad1 and Oprl1 1 0.14 0 1.13
24 INT1620 Negative_regulation of Binding of Gad1 and Oprl1 1 0.16 0 1.13
25 INT131314 crz Regulation of Oprl1 1 0.06 0.08 1.08
26 INT25837 Binding of Dbp and Oprl1 1 0.10 0 1.05
27 INT60047 Oprl1 Negative_regulation of Phosphorylation of Syn1 1 0.05 0.17 1.05
28 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
29 INT34535 Regulation of Binding of Penk and Oprl1 1 0.05 0 1.02
30 INT42555 Oprl1 Negative_regulation of Npr1 1 0.02 0 0.99
31 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
32 INT138072 Chn1 Positive_regulation of Oprl1 1 0.42 1.02 0.95
33 INT42861 Negative_regulation of Binding of Penk and Oprl1 1 0.45 0 0.94
34 INT56431 Vta1 Regulation of Regulation of Oprl1 1 0.07 0 0.89
35 INT64106 Oprl1 Positive_regulation of Localization of Gnrh1 1 0.03 0 0.88
36 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
37 INT44589 Negative_regulation of Oprl1 Positive_regulation of Gh1 1 0.22 0.53 0.87
38 INT44590 Oprl1 Positive_regulation of Gh1 1 0.23 0.53 0.87
39 INT21006 Oprl1 Regulation of Localization of Crh 1 0.19 0 0.84
40 INT40610 Binding of Prkaca and Oprl1 1 0.02 0.09 0.8
41 INT45521 Oprl1 Positive_regulation of Localization of LH 1 0.24 0 0.77
42 INT81520 Binding of PNOC and Oprl1 1 0.24 0.1 0.75
43 INT111506 Negative_regulation of Binding of Oprl1 and Ptprg 1 0.01 0 0.71
44 INT111505 Positive_regulation of Binding of Oprl1 and Ptprg 1 0.01 0 0.71
45 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
46 INT104102 Negative_regulation of Adrbk2 Negative_regulation of Oprl1 1 0.06 0 0.7
47 INT783 Prss12 Positive_regulation of Positive_regulation of Oprl1 1 0.05 0 0.7
48 INT90987 Positive_regulation of Oprl1 Positive_regulation of Binding of Oprl1 1 0.00 0 0.66
49 INT86171 Oprl1 Positive_regulation of Gene_expression of Il2 1 0.30 0 0.64
50 INT69226 Regulation of Pnoc Positive_regulation of Oprl1 1 0.19 0 0.63
51 INT73402 Binding of Oprl1 and Wdyhv1 1 0.00 0 0.61
52 INT73403 Binding of Pdyn and Oprl1 1 0.01 0 0.61
53 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
54 INT109803 Binding of Avp and Oprl1 1 0.07 0.1 0.59
55 INT5990 Positive_regulation of Oprl1 Positive_regulation of Localization of Prl 1 0.17 0 0.59
56 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
57 INT40321 Oprl1 Regulation of Localization of LH 1 0.18 0 0.59
58 INT30483 Binding of Oprl1 and Acyp2-ps1 1 0.02 0 0.58
59 INT123465 Oprl1 Positive_regulation of ATP5G3 1 0.22 0 0.57
60 INT3433 Vip Positive_regulation of Positive_regulation of Oprl1 1 0.26 0 0.53
61 INT85559 Binding of Pnoc and Oprl1 1 0.39 0 0.53
62 INT40186 Binding of Oprl1 and Srms 1 0.01 0 0.52
63 INT62898 Binding of Oprl1 and Dsp 1 0.35 0 0.52
64 INT22273 Nts Regulation of Oprl1 1 0.09 0 0.51
65 INT63279 Binding of Oprl1 and Gpm6a 1 0.01 0 0.47
66 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
67 INT60022 Oprl1 Positive_regulation of Localization of Rhd 1 0.18 0.1 0.44
68 INT83567 Matk Negative_regulation of Oprl1 1 0.00 0 0.42
69 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33
70 INT30525 Acyp2-ps1 Regulation of Oprl1 1 0.04 0.15 0.33
71 INT30523 Pomc Regulation of Oprl1 1 0.06 0.15 0.33
72 INT101562 Binding of TNPO1 and Oprl1 1 0.00 0.12 0.3
73 INT96436 Binding of Npr1 and Oprl1 1 0.05 0 0.29
74 INT29139 ENG Regulation of Oprl1 1 0.00 0 0.28
75 INT65523 Binding of Adarb1 and Oprl1 1 0.02 0 0.28
76 INT29140 POMC Regulation of Oprl1 1 0.00 0 0.27
77 INT65507 Oprl1 Positive_regulation of Gene_expression of Pomc 1 0.28 0 0.26
78 INT84607 Oprl1 Regulation of Adrb3 1 0.19 0.25 0.24
79 INT67992 Binding of Prl and Oprl1 1 0.33 0.16 0.24
80 INT16811 Binding of Scd1 and Oprl1 1 0.00 0 0.24
81 INT144589 Binding of YY1 and Oprl1 1 0.04 0.73 0.13
82 INT108598 Positive_regulation of Oprl1 Positive_regulation of Phosphorylation of P2ry2 1 0.10 0 0.13
83 INT34497 Binding of Oprl1 and Ache 1 0.40 0 0.1
84 INT146721 Nppc Positive_regulation of Positive_regulation of Oprl1 1 0.16 0.34 0.07
85 INT146722 Cnp Positive_regulation of Positive_regulation of Oprl1 1 0.17 0.34 0.07
86 INT90319 Binding of Slc6a3 and Positive_regulation of Regulation of Oprl1 1 0.14 0 0
87 INT74217 Oprl1 Negative_regulation of Positive_regulation of Icam1 1 0.18 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 29256. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 29256. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1212 Binding of Oprl1 312 0.48 28.6 225.15
2 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93
3 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99
4 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74
5 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13
6 INT29477 Transcription of Oprl1 52 0.72 5.05 30.52
7 INT6765 Localization of Oprl1 49 0.81 5.11 28.87
8 INT1334 Negative_regulation of Binding of Oprl1 29 0.59 3.03 20.62
9 INT32910 Positive_regulation of Gene_expression of Oprl1 22 0.70 7.07 19.03
10 INT5987 Positive_regulation of Positive_regulation of Oprl1 11 0.49 2.81 12.57
11 INT1612 Regulation of Binding of Oprl1 19 0.62 2.34 12.45
12 INT18573 Regulation of Positive_regulation of Oprl1 11 0.45 0.78 9.91
13 INT1617 Positive_regulation of Binding of Oprl1 10 0.59 0.63 9.79
14 INT3431 Negative_regulation of Positive_regulation of Oprl1 14 0.46 2.55 9.65
15 INT78432 Negative_regulation of Gene_expression of Oprl1 6 0.58 3.27 7.24
16 INT6764 Regulation of Regulation of Oprl1 5 0.45 0.58 5.28
17 INT40800 Regulation of Gene_expression of Oprl1 8 0.61 1.82 4.73
18 INT42852 Positive_regulation of Transcription of Oprl1 5 0.50 1.06 3.96
19 INT28326 Positive_regulation of Negative_regulation of Oprl1 6 0.44 2.01 3.78
20 INT46986 Negative_regulation of Negative_regulation of Oprl1 5 0.43 0.13 3.37
21 INT90905 Phosphorylation of Oprl1 3 0.50 0.19 2.47
22 INT114848 Regulation of Transcription of Oprl1 3 0.62 1.79 2.44
23 INT121601 Positive_regulation of Localization of Oprl1 1 0.70 1.58 2.22
24 INT85739 Negative_regulation of Regulation of Oprl1 2 0.36 0.46 1.98
25 INT6763 Regulation of Localization of Oprl1 4 0.44 0.25 1.86
26 INT37145 Regulation of Negative_regulation of Oprl1 3 0.23 0.19 1.83
27 INT114847 Negative_regulation of Transcription of Oprl1 4 0.43 0.75 1.69
28 INT33368 Positive_regulation of Regulation of Oprl1 1 0.50 0 0.27
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