G:29527

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Official Symbol Ptgs2
Aliases Cox2, COX-2
EntrezGene 29527
UniProt Coming Soon
Unique Molecular Interactions 33
Total Molecular Interactions 36
Total Single Events 599
Unique Interaction Partners 26

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Ptgs2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Ptgs2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Ptgs2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
2 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
3 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
4 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
5 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
6 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
7 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
8 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
9 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
10 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
11 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
12 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
13 INT89501 Il6 Positive_regulation of Ptgs2 1 0.01 1.07 0.35
14 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
15 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
16 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
17 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
18 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
19 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
20 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22
21 INT141753 Nfkb1 Regulation of Ptgs2 1 0.16 1.18 0.16
22 INT141754 Nfkb1 Regulation of Positive_regulation of Ptgs2 1 0.16 1.21 0.16
23 INT92342 Zfp697 Negative_regulation of Ptgs2 1 0.02 0.63 0.15
24 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14
25 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14
26 INT141113 Sftpa1 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.46 0.32 0.14
27 INT63521 Negative_regulation of Ptgs2 Negative_regulation of Gene_expression of Fos 1 0.66 0.1 0.12
28 INT52701 Slc3a1 Positive_regulation of Ptgs2 1 0.06 0.27 0.11
29 INT52702 Capza2 Positive_regulation of Ptgs2 1 0.00 0.27 0.11
30 INT341882 Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2 1 0.02 0.11 0.05
31 INT17850 Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
32 INT17851 Negative_regulation of Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
33 INT331157 Ptgis Positive_regulation of Ptgs2 1 0.04 0.77 0.03
34 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 29527. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 29527. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
2 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
3 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
4 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
5 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
6 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
7 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
8 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
9 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
10 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
11 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
12 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
13 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
14 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
15 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
16 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
17 INT68265 Positive_regulation of Negative_regulation of Ptgs2 3 0.46 0.08 0.92
18 INT78957 Regulation of Transcription of Ptgs2 1 0.17 0.49 0.72
19 INT92341 Localization of Ptgs2 5 0.75 2.04 0.64
20 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43
21 INT17845 Negative_regulation of Binding of Ptgs2 1 0.09 0.08 0.04
22 INT121544 Positive_regulation of Regulation of Ptgs2 1 0.14 0.15 0
23 INT96041 Positive_regulation of Localization of Ptgs2 1 0.17 0.07 0
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