G:3123

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Official Symbol HLA-DRB1
Aliases SS1, DRB1, DRw10, HLA-DRB, FLJ75017, FLJ76359, HLA-DR1B
EntrezGene 3123
UniProt Coming Soon
Unique Molecular Interactions 25
Total Molecular Interactions 29
Total Single Events 290
Unique Interaction Partners 23

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to HLA-DRB1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to HLA-DRB1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to HLA-DRB1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
2 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
3 INT107263 Binding of HLA-DRB1 and NCR3 1 0.40 1.42 1.1
4 INT169101 Binding of HLA-A and HLA-DRB1 1 0.24 1.09 0.63
5 INT184407 Binding of HLA-DRB1 and HLA-DRB4 2 0.09 2.26 0.4
6 INT184406 Binding of HLA-DRB1 and HLA-E 1 0.00 1.03 0.4
7 INT188391 Binding of CD4 and HLA-DRB1 1 0.05 0.96 0.34
8 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28
9 INT316791 Binding of HLA-DRB1 and Traf1 1 0.01 0.96 0.27
10 INT258906 Binding of HLA-B and HLA-DRB1 1 0.31 1.36 0.15
11 INT171942 Binding of HLA-DRB1 and ATP2C1 1 0.04 2.18 0.12
12 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12
13 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12
14 INT298474 IL4 Positive_regulation of HLA-DRB1 1 0.02 0.33 0.12
15 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12
16 INT236311 IGKV2D-38 Positive_regulation of HLA-DRB1 1 0.02 0.13 0.1
17 INT316793 Binding of HLA-DRB1 and Stat4 1 0.07 0.33 0.08
18 INT316792 Binding of HLA-DRB1 and Ptpn22 1 0.07 0.33 0.08
19 INT262636 Binding of HLA-DRB1 and AICDA 1 0.09 1.35 0.06
20 INT262643 Binding of HLA-DQB1 and HLA-DRB1 1 0.10 0.45 0.05
21 INT337535 HLA-DRB1 Positive_regulation of Trav6-3 1 0.00 1.14 0.04
22 INT283462 Binding of DLAT and HLA-DRB1 1 0.07 1.06 0.03
23 INT251864 Binding of HLA-DRB1 and IGHE 1 0.04 0.23 0
24 INT247113 Positive_regulation of Binding of HLA-DRB1 and MPZ 1 0.03 1.66 0
25 INT236312 IGKV2D-38 Regulation of HLA-DRB1 1 0.01 0.5 0
26 INT247115 Binding of HLA-DRB1 and MPZ 1 0.03 1.66 0
27 INT276137 Binding of COL19A1 and HLA-DRB1 1 0.00 0.62 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3123. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3123. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96
2 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68
3 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26
4 INT18967 Positive_regulation of Gene_expression of HLA-DRB1 14 0.49 13.56 5.99
5 INT89281 Negative_regulation of Gene_expression of HLA-DRB1 10 0.30 5.9 2.55
6 INT14854 Regulation of Gene_expression of HLA-DRB1 10 0.39 5.27 2.19
7 INT236320 Regulation of HLA-DRB1 10 0.45 6 0.69
8 INT64953 Negative_regulation of HLA-DRB1 9 0.58 5.15 0.56
9 INT141706 Localization of HLA-DRB1 9 0.75 4.87 0.48
10 INT56652 Protein_catabolism of HLA-DRB1 1 0.00 1.77 0.19
11 INT6595 Positive_regulation of Positive_regulation of HLA-DRB1 1 0.00 0 0.14
12 INT181462 Transcription of HLA-DRB1 1 0.03 1.41 0.08
13 INT141705 Negative_regulation of Localization of HLA-DRB1 1 0.20 0.27 0.06
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