G:3133

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Official Symbol HLA-E
Aliases MHC, QA1, EA1.2, EA2.1, HLA-6.2, DKFZp686P19218
EntrezGene 3133
UniProt Coming Soon
Unique Molecular Interactions 32
Total Molecular Interactions 59
Total Single Events 525
Unique Interaction Partners 31

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to HLA-E. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to HLA-E. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to HLA-E. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT184402 Binding of HLA-DRB4 and HLA-E 1 0.00 3.1 1.19
2 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
3 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
4 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71
5 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58
6 INT341593 Binding of HLA-E and IL23R 1 0.15 1.15 0.5
7 INT172096 Binding of HLA-E and Il27ra 2 0.01 1.32 0.48
8 INT48848 Binding of HLA-B and HLA-E 3 0.34 1.95 0.45
9 INT184406 Binding of HLA-DRB1 and HLA-E 1 0.00 1.03 0.4
10 INT183924 Binding of CHI3L1 and HLA-E 1 0.08 0.9 0.39
11 INT250951 Binding of HLA-E and SFTPA1 1 0.01 0.44 0.29
12 INT174499 Binding of CD4 and HLA-E 1 0.04 1.08 0.29
13 INT260870 Binding of HLA-E and IL7R 1 0.19 0.5 0.22
14 INT194134 Binding of HLA-E and IGAD1 1 0.02 1.01 0.15
15 INT194136 Binding of HLA-E and INS 1 0.01 0.95 0.15
16 INT194135 Binding of CD79A and HLA-E 1 0.07 1.01 0.15
17 INT289629 Binding of HLA-DMB and HLA-E 1 0.10 0.84 0.11
18 INT289627 Binding of HLA-E and RS1 1 0.01 0.83 0.11
19 INT289623 Binding of HLA-E and RS1 Regulation of Binding of RS1 1 0.00 0.84 0.11
20 INT289622 Binding of HLA-DMB and HLA-E Regulation of Binding of RS1 1 0.01 0.84 0.11
21 INT294116 CIITA Regulation of Gene_expression of HLA-E 1 0.05 0.05 0.08
22 INT356238 Binding of HLA-E and PI3 1 0.02 0 0.05
23 INT177948 IFNG Positive_regulation of Gene_expression of HLA-E 1 0.04 0.59 0.03
24 INT177947 IFN1@ Positive_regulation of Gene_expression of HLA-E 1 0.09 0.59 0.03
25 INT207031 Binding of HLA-C and HLA-E 1 0.35 0.1 0
26 INT276136 Binding of DIO2 and HLA-E 1 0.26 0 0
27 INT336764 ERAP2 Regulation of Gene_expression of HLA-E 1 0.24 0 0
28 INT275123 Binding of HLA-E and SUGT1 1 0.00 0.93 0
29 INT164332 Binding of HLA-E and KLRC2 1 0.00 0 0
30 INT301675 Binding of APC and HLA-E 1 0.01 1.48 0
31 INT276138 Binding of COL19A1 and HLA-E 1 0.01 0.62 0
32 INT349077 Binding of HLA-E and KLRD1 1 0.00 0.16 0
33 INT336762 Negative_regulation of ERAP2 Negative_regulation of HLA-E 1 0.23 0.31 0
34 INT301676 Binding of CD8A and HLA-E 1 0.02 2.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3133. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3133. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72
2 INT11699 Binding of HLA-E 85 0.47 52.51 13.41
3 INT28671 Positive_regulation of Gene_expression of HLA-E 43 0.67 22.85 8.39
4 INT64767 Negative_regulation of Gene_expression of HLA-E 18 0.57 12.64 5.23
5 INT15797 Positive_regulation of HLA-E 36 0.67 15.17 5.07
6 INT174195 Negative_regulation of HLA-E 31 0.42 11.98 3.88
7 INT50006 Regulation of HLA-E 12 0.44 8.78 2.37
8 INT69398 Regulation of Gene_expression of HLA-E 14 0.60 3.54 1.27
9 INT177951 Transcription of HLA-E 7 0.67 2.36 0.52
10 INT177954 Negative_regulation of Positive_regulation of HLA-E 2 0.07 0.61 0.33
11 INT188706 Localization of HLA-E 8 0.33 2.43 0.32
12 INT294137 Positive_regulation of Positive_regulation of HLA-E 1 0.09 0.33 0.2
13 INT177956 Positive_regulation of Transcription of HLA-E 3 0.49 1.02 0.19
14 INT197053 Negative_regulation of Binding of HLA-E 1 0.20 1.07 0.12
15 INT254338 Positive_regulation of Localization of HLA-E 1 0.03 0.26 0.03
16 INT351824 Regulation of Binding of HLA-E 1 0.03 0.89 0.03
17 INT356246 Negative_regulation of Transcription of HLA-E 1 0.41 0.05 0.03
18 INT308196 Negative_regulation of Negative_regulation of HLA-E 1 0.28 0 0
19 INT276139 Regulation of Negative_regulation of HLA-E 1 0.39 0.07 0
20 INT275143 Positive_regulation of Binding of HLA-E 1 0.16 0.32 0
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