G:3146

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Official Symbol HMGB1
Aliases HMG1, HMG3, SBP-1, DKFZp686A04236
EntrezGene 3146
UniProt Coming Soon
Unique Molecular Interactions 15
Total Molecular Interactions 26
Total Single Events 137
Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to HMGB1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to HMGB1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to HMGB1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
2 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
3 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
4 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37
5 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24
6 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23
7 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2
8 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2
9 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2
10 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2
11 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2
12 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16
13 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14
14 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14
15 INT301246 Binding of HMGB1 and Hbp1 1 0.03 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3146. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3146. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55
2 INT184288 Localization of HMGB1 20 0.61 14.5 3.84
3 INT184272 Binding of HMGB1 14 0.37 8.78 2.49
4 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58
5 INT184271 Positive_regulation of Gene_expression of HMGB1 7 0.41 6.17 1.53
6 INT219168 Positive_regulation of Localization of HMGB1 5 0.36 4 1.16
7 INT184277 Regulation of Localization of HMGB1 1 0.37 1.15 0.58
8 INT343799 Negative_regulation of Transcription of HMGB1 1 0.32 0.37 0.5
9 INT220339 Transcription of HMGB1 2 0.53 2.03 0.49
10 INT219178 Negative_regulation of Localization of HMGB1 1 0.22 1.26 0.45
11 INT220336 Negative_regulation of HMGB1 3 0.43 0.97 0.21
12 INT266367 Positive_regulation of Binding of HMGB1 1 0.26 0.31 0.21
13 INT266364 Protein_catabolism of HMGB1 1 0.34 0.29 0.19
14 INT266353 Negative_regulation of Binding of HMGB1 1 0.22 0.22 0.17
15 INT206737 Negative_regulation of Gene_expression of HMGB1 3 0.32 3.48 0.09
16 INT299469 Regulation of HMGB1 2 0.18 2.27 0.03
17 INT266358 Regulation of Binding of HMGB1 1 0.14 0 0.03
18 INT299470 Regulation of Gene_expression of HMGB1 1 0.18 1.58 0
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