G:3156

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Official Symbol HMGCR
Aliases LDLCQ3
EntrezGene 3156
UniProt Coming Soon
Unique Molecular Interactions 7
Total Molecular Interactions 7
Total Single Events 78
Unique Interaction Partners 5

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to HMGCR. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to HMGCR. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to HMGCR. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
2 INT176020 IL8 Negative_regulation of Phosphorylation of HMGCR 1 0.00 0.1 0.11
3 INT233323 GAD1 Regulation of HMGCR 1 0.09 0.2 0
4 INT339693 HMGCR Positive_regulation of SREBF2 1 0.05 0.54 0
5 INT326064 APOA1 Positive_regulation of HMGCR 1 0.16 0.19 0
6 INT339709 HMGCR Positive_regulation of Gene_expression of SREBF2 1 0.05 0.54 0
7 INT326066 APOA1 Positive_regulation of Positive_regulation of HMGCR 1 0.17 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3156. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3156. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94
2 INT142695 Gene_expression of HMGCR 17 0.65 3.75 0.32
3 INT176039 Regulation of HMGCR 6 0.17 2.32 0.29
4 INT176036 Phosphorylation of HMGCR 1 0.05 0.19 0.22
5 INT176038 Binding of HMGCR 1 0.03 0.72 0.14
6 INT197011 Regulation of Gene_expression of HMGCR 1 0.32 0.09 0.08
7 INT176037 Transcription of HMGCR 2 0.37 0.07 0.04
8 INT176040 Negative_regulation of Transcription of HMGCR 1 0.04 0.07 0.04
9 INT176033 Positive_regulation of HMGCR 8 0.33 2.56 0.03
10 INT243183 Regulation of Negative_regulation of HMGCR 1 0.15 0.06 0.03
11 INT197015 Positive_regulation of Gene_expression of HMGCR 2 0.29 0.76 0
12 INT197013 Localization of HMGCR 1 0.36 0 0
13 INT258070 Positive_regulation of Regulation of HMGCR 1 0.10 0.44 0
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