G:324

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Official Symbol APC
Aliases GS, DP2, DP3, BTPS2, DP2.5, PPP1R46
EntrezGene 324
UniProt Coming Soon
Unique Molecular Interactions 41
Total Molecular Interactions 55
Total Single Events 399
Unique Interaction Partners 32

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to APC. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to APC. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to APC. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
2 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
3 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
4 INT84885 APC Regulation of APC Regulation of PPARD 1 0.18 0.55 0.41
5 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
6 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
7 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
8 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
9 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
10 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
11 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
12 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
13 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
14 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
15 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
16 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
17 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
18 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
19 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
20 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
21 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
22 INT299763 Binding of APC and CTLA4 Positive_regulation of Ido1 1 0.11 0.31 0.14
23 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
24 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
25 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
26 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
27 INT262255 Binding of APC and F2R 1 0.05 3 0.1
28 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04
29 INT301675 Binding of APC and HLA-E 1 0.01 1.48 0
30 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
31 INT301674 Binding of APC and CD80 1 0.01 0.53 0
32 INT195661 Binding of APC and PROC 1 0.23 0.89 0
33 INT253019 APC Positive_regulation of Protein_catabolism of Pttg1 1 0.06 0 0
34 INT253012 APC Positive_regulation of Binding of Pttg1 1 0.06 0 0
35 INT268342 Binding of APC and ANKS1B 1 0.01 0.92 0
36 INT301677 Binding of APC and CD8A 1 0.03 1.48 0
37 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
38 INT268395 Binding of APC and Kras 1 0.04 1.21 0
39 INT80660 INS Positive_regulation of APC 1 0.32 0.65 0
40 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0
41 INT195659 APC Positive_regulation of Gene_expression of PROC 1 0.26 0.31 0
42 INT265230 Binding of APC and FKBP1A Regulation of APC 1 0.01 0.41 0
43 INT80659 Positive_regulation of INS Positive_regulation of APC 1 0.32 0.65 0
44 INT252909 FZR1 Positive_regulation of APC 1 0.06 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 324. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 324. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
2 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
3 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
4 INT63121 Binding of APC 29 0.41 23.02 3.8
5 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
6 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
7 INT57062 Regulation of APC 24 0.58 14.3 0.7
8 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
9 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
10 INT118243 Transcription of APC 4 0.45 3.33 0.33
11 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
12 INT195672 Localization of APC 7 0.74 3.76 0.3
13 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
14 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
15 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
16 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
17 INT268372 Phosphorylation of APC 3 0.81 3.39 0.09
18 INT195679 Positive_regulation of Positive_regulation of APC 6 0.50 4.43 0.05
19 INT195681 Positive_regulation of Negative_regulation of APC 5 0.47 3.9 0
20 INT337657 Negative_regulation of Negative_regulation of APC 1 0.37 0.99 0
21 INT337673 Regulation of Positive_regulation of APC 1 0.38 1.44 0
22 INT283365 Positive_regulation of Binding of APC 1 0.50 1.43 0
23 INT337667 Regulation of Transcription of APC 1 0.23 1 0
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