G:3383

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Official Symbol ICAM1
Aliases BB2, CD54, P3.58
EntrezGene 3383
UniProt Coming Soon
Unique Molecular Interactions 72
Total Molecular Interactions 141
Total Single Events 1213
Unique Interaction Partners 47

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ICAM1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ICAM1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ICAM1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
2 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
3 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
4 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
5 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
6 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
7 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
8 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
9 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
10 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
11 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
12 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
13 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
14 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
15 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
16 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
17 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
18 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
19 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
20 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
21 INT137137 Binding of HIVEP1 and ICAM1 1 0.01 0.68 0.51
22 INT92997 Positive_regulation of SFTPA1 Positive_regulation of Binding of ICAM1 1 0.15 0.26 0.51
23 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
24 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
25 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37
26 INT78893 TNF Regulation of Gene_expression of ICAM1 1 0.24 0.38 0.35
27 INT222974 NFKBIB Negative_regulation of NFKB2 Negative_regulation of ICAM1 1 0.00 1.6 0.33
28 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27
29 INT129220 IFNG Positive_regulation of ICAM1 1 0.09 0.1 0.25
30 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25
31 INT129219 IFNG Positive_regulation of Gene_expression of ICAM1 1 0.13 0.1 0.25
32 INT284589 Binding of ICAM1 and Crp 1 0.00 1.08 0.22
33 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
34 INT141490 Negative_regulation of TNF Positive_regulation of ICAM1 1 0.29 0.58 0.21
35 INT158199 Negative_regulation of Binding of ICAM1 and AHSA1 1 0.15 0.3 0.2
36 INT158220 Positive_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
37 INT158223 Binding of ICAM1 and TNFSF14 1 0.04 0.3 0.2
38 INT158218 Binding of ICAM1 and AHSA1 1 0.14 0.3 0.2
39 INT158227 Negative_regulation of Binding of ICAM1 and MAPK1 1 0.16 0.3 0.2
40 INT158236 Positive_regulation of Binding of ICAM1 and MAPK1 1 0.19 0.3 0.2
41 INT158226 Binding of ICAM1 and MAPK1 1 0.14 0.3 0.2
42 INT158213 Positive_regulation of Binding of ICAM1 and AHSA1 1 0.18 0.3 0.2
43 INT158229 Negative_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
44 INT125152 IL1B Regulation of Gene_expression of ICAM1 1 0.50 0.1 0.2
45 INT158215 TNFSF14 Positive_regulation of ICAM1 1 0.05 0.3 0.2
46 INT214590 TIMP1 Regulation of ICAM1 1 0.10 0.29 0.19
47 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
48 INT214592 OAP Regulation of Gene_expression of ICAM1 1 0.02 0.77 0.19
49 INT171945 PECAM1 Positive_regulation of Gene_expression of ICAM1 1 0.06 1.66 0.16
50 INT171544 PECAM1 Positive_regulation of ICAM1 1 0.01 0.47 0.16
51 INT171944 ICAM1 Positive_regulation of Gene_expression of PECAM1 1 0.06 1.66 0.16
52 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
53 INT269785 Crp Positive_regulation of ICAM1 1 0.00 1.68 0.11
54 INT297938 Binding of ICAM1 and PAOD1 1 0.06 0.86 0.11
55 INT120700 PRSS1 Positive_regulation of ICAM1 1 0.15 0.29 0.1
56 INT355580 VEGFA Positive_regulation of ICAM1 1 0.09 1.39 0.09
57 INT267626 Il1 Positive_regulation of ICAM1 1 0.00 0.79 0.09
58 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
59 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07
60 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 0.06 0.2 0.07
61 INT284503 Binding of ICAM1 and ITGAM 1 0.05 0.2 0.07
62 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07
63 INT313506 Binding of ICAM1 and SNRNP70 1 0.02 1.08 0.06
64 INT313501 Binding of ALOX12 and ICAM1 1 0.10 0.54 0.03
65 INT285407 ELF3 Regulation of ICAM1 1 0.03 0.91 0.03
66 INT251006 ICAM1 Positive_regulation of SELL 1 0.02 0.56 0
67 INT170587 GOPC Regulation of Gene_expression of ICAM1 1 0.13 0 0
68 INT249996 Binding of ICAM1 and GPHA2 1 0.02 2.25 0
69 INT249995 Positive_regulation of Binding of ICAM1 and GPHA2 1 0.02 2.43 0
70 INT170590 RELA Negative_regulation of Gene_expression of ICAM1 1 0.42 0.49 0
71 INT170588 RELA Regulation of Gene_expression of ICAM1 1 0.26 0 0
72 INT170589 NFKB1 Regulation of Gene_expression of ICAM1 1 0.27 0 0
73 INT155171 ICAM1 Regulation of Gene_expression of NOS1 1 0.09 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3383. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3383. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
2 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
3 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
4 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
5 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
6 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
7 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
8 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
9 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
10 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
11 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55
12 INT93005 Positive_regulation of Binding of ICAM1 5 0.68 4.55 1.42
13 INT62824 Negative_regulation of Positive_regulation of ICAM1 7 0.53 2.94 1.39
14 INT63339 Transcription of ICAM1 6 0.69 3.92 1.37
15 INT66607 Regulation of Positive_regulation of ICAM1 3 0.42 2.81 0.71
16 INT78813 Positive_regulation of Transcription of ICAM1 1 0.46 0.16 0.5
17 INT158244 Phosphorylation of ICAM1 2 0.67 1.33 0.39
18 INT177231 Regulation of Regulation of ICAM1 1 0.06 0.66 0.37
19 INT267145 Negative_regulation of Binding of ICAM1 5 0.57 4.12 0.33
20 INT214613 Regulation of Binding of ICAM1 2 0.28 1.41 0.32
21 INT214610 Regulation of Localization of ICAM1 1 0.28 0 0.11
22 INT267150 Regulation of Transcription of ICAM1 2 0.26 0.86 0.06
23 INT139002 Negative_regulation of Negative_regulation of ICAM1 1 0.02 0.1 0
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