G:3439

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Official Symbol IFNA1
Aliases IFL, IFN, IFNA@, IFNA13, IFN-ALPHA, MGC138207, MGC138505, MGC138507, IFN-alphaD
EntrezGene 3439
UniProt Coming Soon
Unique Molecular Interactions 171
Total Molecular Interactions 227
Total Single Events 2475
Unique Interaction Partners 113

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IFNA1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IFNA1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IFNA1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
2 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
3 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19
4 INT32152 POMC Positive_regulation of Gene_expression of IFNA1 2 0.67 0 1.53
5 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
6 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
7 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
8 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
9 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
10 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
11 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
12 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
13 INT103277 MGAT5B Positive_regulation of Gene_expression of IFNA1 1 0.01 0.87 0.78
14 INT201941 IFNA1 Positive_regulation of Gene_expression of CXCL10 1 0.14 1.09 0.74
15 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74
16 INT122028 Binding of IFNA1 and Oprd1 1 0.01 0.41 0.69
17 INT122029 Binding of Oprd1 and Positive_regulation of IFNA1 1 0.01 0.4 0.68
18 INT76089 IFNA1 Negative_regulation of Positive_regulation of ISYNA1 1 0.27 0.05 0.65
19 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64
20 INT76087 IFNA1 Negative_regulation of ISYNA1 1 0.27 0.06 0.63
21 INT176365 IL12A Positive_regulation of Gene_expression of IFNA1 1 0.13 1.35 0.6
22 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57
23 INT176367 LBR Positive_regulation of IFNA1 1 0.02 1.22 0.55
24 INT174467 IL7 Positive_regulation of IFNA1 1 0.11 1.53 0.53
25 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
26 INT33349 Binding of IFNA1 and Oprl1 1 0.09 0.08 0.52
27 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52
28 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51
29 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5
30 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46
31 INT176366 LBR Regulation of IFNA1 1 0.04 0.91 0.46
32 INT288350 IFNA1 Positive_regulation of Localization of Il6 1 0.01 1.49 0.46
33 INT176364 IL12A Regulation of Positive_regulation of IFNA1 1 0.12 0.59 0.46
34 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46
35 INT302421 IFNA1 Positive_regulation of Cxcl10 1 0.02 1.8 0.45
36 INT302422 IFNA1 Positive_regulation of Cxcl9 1 0.03 1.81 0.45
37 INT302423 Etohi5 Positive_regulation of IFNA1 1 0.00 1.77 0.44
38 INT33348 Binding of IFNA1 and Pomc 1 0.27 0.09 0.41
39 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4
40 INT61954 IFNA1 Positive_regulation of Nos2 1 0.05 0.46 0.38
41 INT59845 Negative_regulation of IFNA1 Positive_regulation of Gpi1 1 0.09 0 0.37
42 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37
43 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37
44 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37
45 INT59844 IFNA1 Positive_regulation of Gpi1 1 0.10 0 0.37
46 INT59843 IFNA1 Positive_regulation of IFNA1 Positive_regulation of Gpi1 1 0.05 0 0.37
47 INT176363 IFNA1 Regulation of Positive_regulation of LBR 1 0.04 0.69 0.34
48 INT315400 IFNA1 Positive_regulation of Phosphorylation of Stat1 1 0.02 0.4 0.33
49 INT188707 Binding of IFNA1 and Hand1 1 0.01 0.56 0.32
50 INT76088 IFNA1 Positive_regulation of IRF6 1 0.19 0.18 0.31
51 INT285105 Gene_expression of PMP2 Positive_regulation of IFNA1 1 0.05 0.93 0.31
52 INT285100 PMP2 Positive_regulation of IFNA1 1 0.05 0.93 0.31
53 INT285099 Gene_expression of SLC10A7 Positive_regulation of IFNA1 1 0.10 0.93 0.31
54 INT285101 SLC10A7 Positive_regulation of IFNA1 1 0.05 0.93 0.31
55 INT315394 IFNA1 Positive_regulation of Gene_expression of Socs1 1 0.01 0.41 0.31
56 INT76090 IFNA1 Positive_regulation of ISYNA1 1 0.30 0.18 0.31
57 INT345421 IFNA1 Positive_regulation of Eif2ak2 2 0.03 1.25 0.3
58 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
59 INT324830 Hspd1 Positive_regulation of IFNA1 1 0.04 0.46 0.3
60 INT315392 IFNA1 Positive_regulation of Stat1 1 0.02 0.4 0.3
61 INT315398 IFNA1 Positive_regulation of Socs1 1 0.01 0.41 0.3
62 INT184141 Il6 Positive_regulation of Gene_expression of IFNA1 1 0.01 0.43 0.28
63 INT176372 Positive_regulation of IL18 Positive_regulation of IFNA1 1 0.16 0.36 0.28
64 INT32147 LLGL1 Positive_regulation of Gene_expression of IFNA1 1 0.13 0 0.27
65 INT163301 Binding of IFNA1 and IL6 2 0.04 2.95 0.26
66 INT226343 Binding of IFNA1 and IL26 1 0.02 0.18 0.26
67 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
68 INT315393 Bdnf Positive_regulation of Gene_expression of IFNA1 1 0.01 0.37 0.26
69 INT280008 Binding of IFNA1 and PAEP 2 0.08 1.29 0.25
70 INT254598 Il12a Positive_regulation of Gene_expression of IFNA1 1 0.11 0.4 0.25
71 INT311968 TNF Regulation of Transcription of IFNA1 1 0.01 0.59 0.25
72 INT324835 Hspd1 Positive_regulation of Gene_expression of IFNA1 1 0.15 0.31 0.23
73 INT334269 Iars Negative_regulation of Gene_expression of IFNA1 1 0.03 0.62 0.23
74 INT346455 IFNA1 Regulation of HCC 1 0.02 1.64 0.23
75 INT35014 IFNA1 Positive_regulation of ADI1 1 0.03 0.17 0.23
76 INT69040 Casp1 Negative_regulation of Gene_expression of IFNA1 1 0.07 0.17 0.22
77 INT172083 TNF Regulation of Regulation of IFNA1 1 0.03 0.91 0.22
78 INT69039 Negative_regulation of Casp1 Negative_regulation of Gene_expression of IFNA1 1 0.07 0.17 0.22
79 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22
80 INT260440 Negative_regulation of Tlr9 Negative_regulation of Positive_regulation of IFNA1 1 0.03 0.96 0.21
81 INT260441 Negative_regulation of Tlr7 Negative_regulation of Positive_regulation of IFNA1 1 0.05 0.96 0.21
82 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21
83 INT170729 NGF Positive_regulation of Gene_expression of IFNA1 1 0.04 0.15 0.2
84 INT348041 Binding of IFNA1 and Irf3 1 0.02 1.41 0.2
85 INT285102 PMP2 Regulation of IFNA1 1 0.04 0.56 0.19
86 INT353298 IFNA1 Positive_regulation of CD8A 1 0.04 0.75 0.19
87 INT329068 Tlr9 Positive_regulation of Localization of IFNA1 1 0.03 1.54 0.19
88 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
89 INT182151 ITGAX Positive_regulation of Binding of IFNA1 1 0.05 0.46 0.18
90 INT182152 DCPS Positive_regulation of IFNA1 1 0.02 0.45 0.18
91 INT222661 IFNA1 Positive_regulation of Gene_expression of Nos1 1 0.01 0.25 0.18
92 INT252606 IFNA1 Positive_regulation of Gene_expression of Cxcl10 1 0.02 0.56 0.18
93 INT182149 DCPS Positive_regulation of Binding of IFNA1 1 0.02 0.45 0.18
94 INT182157 ITGAX Positive_regulation of IFNA1 1 0.05 0.46 0.18
95 INT69038 Casp1 Regulation of Gene_expression of IFNA1 1 0.07 0.16 0.18
96 INT226522 Nfatc3 Positive_regulation of Gene_expression of IFNA1 1 0.05 0.19 0.17
97 INT315396 Adcyap1 Regulation of IFNA1 1 0.02 0.14 0.17
98 INT213072 Binding of IFNA1 and ACCS 1 0.06 3.85 0.17
99 INT295439 Binding of AES and IFNA1 1 0.25 0.46 0.17
100 INT243677 IL-17 Regulation of IFNA1 1 0.01 0.21 0.16
101 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15
102 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
103 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15
104 INT346450 Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
105 INT174470 IL4 Negative_regulation of IFNA1 1 0.09 0.27 0.14
106 INT226354 ST2 Positive_regulation of Gene_expression of IFNA1 1 0.04 0.15 0.12
107 INT254229 Binding of Ticam1 and Positive_regulation of Binding of IFNA1 1 0.02 0.3 0.12
108 INT186379 Il12a Positive_regulation of Binding of IFNA1 1 0.03 0.07 0.12
109 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
110 INT226532 T Positive_regulation of Gene_expression of IFNA1 1 0.01 0.15 0.12
111 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
112 INT7204 Binding of IFNA1 and IFNG 1 0.01 1.34 0.11
113 INT174463 IL7 Regulation of Gene_expression of IFNA1 1 0.04 0.21 0.11
114 INT202544 Binding of IFNA1 and IL4 1 0.00 0.49 0.11
115 INT174471 IL4 Regulation of Gene_expression of IFNA1 1 0.06 0.21 0.11
116 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1
117 INT228333 Binding of IFNA1 and IRF9 2 0.04 0.53 0.09
118 INT319002 CSF2 Positive_regulation of Gene_expression of IFNA1 1 0.05 1.02 0.09
119 INT249601 IFNA1 Negative_regulation of Gene_expression of Cd40 1 0.42 0.51 0.09
120 INT228350 IFNA1 Positive_regulation of Transcription of Irf2 1 0.04 0.27 0.09
121 INT280004 Binding of IFNA1 and CDIPT 1 0.01 0.74 0.08
122 INT190529 IFNA1 Positive_regulation of Transcription of TRIM63 1 0.00 0.39 0.08
123 INT253930 IFNA1 Positive_regulation of Cdc42ep3 1 0.00 0.65 0.08
124 INT222812 NDUFA6 Negative_regulation of Gene_expression of IFNA1 1 0.00 0.22 0.08
125 INT290166 Atp6v1e1 Positive_regulation of IFNA1 1 0.07 0 0.08
126 INT271284 Binding of IFNA1 and Stat1 1 0.07 0.7 0.08
127 INT320354 IFNA1 Regulation of Cd69 1 0.01 0.2 0.07
128 INT260442 Binding of IFNA1 and Il6 1 0.01 1.07 0.07
129 INT260439 Positive_regulation of Binding of IFNA1 and Il6 1 0.01 1.08 0.07
130 INT194683 Negative_regulation of MAPK1 Negative_regulation of IFNA1 1 0.02 0.07 0.07
131 INT297562 TNF Positive_regulation of IFNA1 1 0.00 0.62 0.06
132 INT315399 Adcyap1 Positive_regulation of Binding of IFNA1 1 0.02 0 0.06
133 INT354822 Negative_regulation of Stat3 Negative_regulation of Positive_regulation of IFNA1 1 0.02 0.85 0.06
134 INT346457 IRF3 Positive_regulation of IFNA1 1 0.03 0.56 0.05
135 INT320353 IFNA1 Positive_regulation of Gene_expression of Ighg2b 1 0.02 0 0.05
136 INT319000 Binding of CSF2 and IFNA1 1 0.03 1.76 0.05
137 INT290165 Tlr9 Positive_regulation of Gene_expression of IFNA1 1 0.10 1.2 0.04
138 INT331172 Binding of IFNA1 and IL2 1 0.00 0.46 0.04
139 INT348819 Ica1 Positive_regulation of Gene_expression of IFNA1 1 0.01 0.21 0.04
140 INT330372 Ifx Positive_regulation of IFNA1 1 0.54 0.67 0.04
141 INT186387 IFNA1 Positive_regulation of Transcription of Nos2 1 0.03 0.7 0.04
142 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03
143 INT186384 Il4 Negative_regulation of Gene_expression of IFNA1 1 0.01 0.48 0.03
144 INT333636 Rai1 Negative_regulation of Gene_expression of IFNA1 1 0.05 1.16 0.03
145 INT240586 IRF7 Positive_regulation of Positive_regulation of IFNA1 1 0.01 0.44 0.03
146 INT333631 Thse Negative_regulation of Gene_expression of IFNA1 1 0.00 1.15 0.03
147 INT254375 Binding of IFNA1 and MRC1 1 0.00 0.87 0
148 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
149 INT194690 MAPK1 Regulation of IFNA1 1 0.02 0 0
150 INT186378 IFNA1 Positive_regulation of Il12a 1 0.03 0.76 0
151 INT105009 Binding of IFNA1 and Oprm1 1 0.01 0 0
152 INT98350 Positive_regulation of IFNA1 Positive_regulation of SGCG 1 0.14 0.23 0
153 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
154 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
155 INT290168 Atp6v1e1 Regulation of Localization of IFNA1 1 0.07 0.19 0
156 INT280006 Binding of CLTC and IFNA1 1 0.04 1.59 0
157 INT290170 Atp6v1e1 Positive_regulation of Gene_expression of IFNA1 1 0.07 0.15 0
158 INT98348 IFNA1 Positive_regulation of SGCG 1 0.14 0.22 0
159 INT290169 Binding of IFNA1 and Pdc 1 0.05 0.32 0
160 INT300079 IL12A Positive_regulation of Positive_regulation of IFNA1 1 0.05 2.14 0
161 INT300063 IL12A Positive_regulation of IL12A Positive_regulation of IFNA1 1 0.03 2.14 0
162 INT271287 Gene_expression of IFNA1 Positive_regulation of Insr 1 0.03 0.51 0
163 INT98349 IFNA1 Positive_regulation of Gene_expression of SGCG 1 0.14 0.22 0
164 INT138260 Csi Regulation of IFNA1 1 0.00 0.06 0
165 INT271288 Ifng Positive_regulation of Transcription of IFNA1 1 0.07 0.93 0
166 INT186388 Binding of IFNA1 and Ifnz 1 0.05 0.51 0
167 INT186376 IFNA1 Positive_regulation of Il18 1 0.02 0.76 0
168 INT290167 Atp6v1e1 Positive_regulation of Localization of IFNA1 1 0.07 0.33 0
169 INT217314 IFNA1 Positive_regulation of MAVS 1 0.01 1.47 0
170 INT271286 IFNA1 Positive_regulation of Stat1 1 0.09 0.14 0
171 INT186389 IFNA1 Regulation of Positive_regulation of Nos2 1 0.02 1.38 0
172 INT265390 IFIH1 Positive_regulation of Regulation of IFNA1 1 0.00 0.08 0
173 INT32150 POMC Regulation of Gene_expression of IFNA1 1 0.36 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3439. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3439. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03
2 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52
3 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87
4 INT6302 Binding of IFNA1 196 0.48 133.85 32.73
5 INT55583 Localization of IFNA1 135 0.78 85.07 24.13
6 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52
7 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08
8 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25
9 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61
10 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62
11 INT139329 Phosphorylation of IFNA1 24 0.79 16.19 5.95
12 INT26069 Positive_regulation of Positive_regulation of IFNA1 26 0.50 16.61 4.76
13 INT173519 Positive_regulation of Localization of IFNA1 27 0.49 24.48 3.9
14 INT176443 Regulation of Localization of IFNA1 11 0.44 7.29 3.4
15 INT89308 Positive_regulation of Binding of IFNA1 12 0.49 10.64 2.04
16 INT38118 Negative_regulation of Positive_regulation of IFNA1 8 0.43 3.95 2.04
17 INT122888 Positive_regulation of Transcription of IFNA1 5 0.45 3.51 1.59
18 INT314586 Regulation of Transcription of IFNA1 3 0.04 1.45 1.39
19 INT128769 Negative_regulation of Localization of IFNA1 8 0.24 6.85 1.35
20 INT60741 Regulation of Positive_regulation of IFNA1 9 0.16 6.98 1.24
21 INT174485 Protein_catabolism of IFNA1 3 0.96 2.17 1.11
22 INT178209 Negative_regulation of Binding of IFNA1 7 0.39 4.8 0.89
23 INT59033 Regulation of Regulation of IFNA1 3 0.42 2.4 0.8
24 INT316728 Positive_regulation of Protein_catabolism of IFNA1 1 0.67 1.07 0.75
25 INT316729 Positive_regulation of Phosphorylation of IFNA1 2 0.49 1.86 0.72
26 INT311977 Regulation of Negative_regulation of IFNA1 3 0.13 1.79 0.64
27 INT83152 Negative_regulation of Negative_regulation of IFNA1 2 0.15 0.97 0.51
28 INT299802 Negative_regulation of Transcription of IFNA1 2 0.09 0.54 0.41
29 INT77364 Positive_regulation of Negative_regulation of IFNA1 6 0.30 3.68 0.36
30 INT278065 Negative_regulation of Phosphorylation of IFNA1 2 0.39 0.68 0.31
31 INT219189 Positive_regulation of Regulation of IFNA1 2 0.10 0.53 0.13
32 INT279346 Regulation of Binding of IFNA1 3 0.31 3.3 0
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