G:3479

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Official Symbol IGF1
Aliases IGFI, IGF-I, IGF1A
EntrezGene 3479
UniProt Coming Soon
Unique Molecular Interactions 91
Total Molecular Interactions 145
Total Single Events 1401
Unique Interaction Partners 47

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IGF1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IGF1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IGF1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
2 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
3 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
4 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
5 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
6 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
7 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
8 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
9 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
10 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
11 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
12 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
13 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
14 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
15 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
16 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
17 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
18 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31
19 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
20 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.29
21 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28
22 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28
23 INT142884 IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.28
24 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26
25 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23
26 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
27 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21
28 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21
29 INT173945 Hrt1 Positive_regulation of Positive_regulation of IGF1 1 0.01 0.32 0.21
30 INT220146 Binding of IGF1 and IGFBP1 2 0.10 1.57 0.19
31 INT173943 Binding of IGF1 and Il6 1 0.04 0.11 0.19
32 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
33 INT59952 Gh Positive_regulation of IGF1 1 0.46 0.84 0.16
34 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16
35 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15
36 INT45371 IGF1 Regulation of Smc1b 1 0.08 0 0.14
37 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14
38 INT45370 IGF1 Regulation of Gh1 1 0.13 0 0.14
39 INT68753 IGF1 Regulation of Gene_expression of Gh 2 0.02 0.68 0.13
40 INT220147 IGFBP3 Positive_regulation of IGF1 1 0.10 0.53 0.13
41 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11
42 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
43 INT323875 Binding of BMI1 and IGF1 1 0.01 1.2 0.11
44 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1
45 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1
46 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 0.14 0.18 0.1
47 INT137368 Retn Positive_regulation of Gene_expression of IGF1 1 0.00 0.17 0.1
48 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1
49 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09
50 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
51 INT265878 IGF1 Negative_regulation of Binding of BCL2 and BCL2L11 1 0.03 1.03 0.09
52 INT192293 Binding of IGF1 and IL1B 1 0.15 0.08 0.08
53 INT312219 Binding of IGF1 and IGFBP5 1 0.02 0.13 0.08
54 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
55 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07
56 INT70762 IGF1 Regulation of Gh 1 0.00 0.17 0.07
57 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07
58 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 0.03 0.47 0.07
59 INT51273 IGF1 Positive_regulation of IGFBP2 1 0.37 0.13 0.06
60 INT78445 Binding of GHRH and IGF1 1 0.20 0.72 0.06
61 INT51276 IGF1 Negative_regulation of GH1 1 0.10 0.13 0.06
62 INT51274 IGF1 Negative_regulation of IGF2 1 0.28 0.13 0.06
63 INT234619 IGF1 Regulation of IGF1R 1 0.11 0.39 0.05
64 INT218614 INS Positive_regulation of Binding of IGF1 1 0.39 0.79 0.05
65 INT339779 IGF1 Regulation of GHRH 1 0.08 0.38 0.05
66 INT234624 Binding of IGF1 and IGF1R 1 0.09 0.39 0.05
67 INT234620 Regulation of Binding of IGF1 and IGF1R 1 0.07 0.39 0.05
68 INT202233 IGFBP1 Regulation of IGF1 1 0.22 0.19 0.04
69 INT202231 Binding of IGF1 and INS 2 0.28 1.38 0.03
70 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03
71 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03
72 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03
73 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03
74 INT208410 IGF1 Positive_regulation of TXK 1 0.08 0.9 0.03
75 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03
76 INT174532 PTH Positive_regulation of Transcription of IGF1 1 0.06 0.51 0
77 INT299626 Binding of IGF1 and IGFBP3 Positive_regulation of IGF1 1 0.02 0.39 0
78 INT206854 ESR1 Regulation of IGF1 1 0.01 0.33 0
79 INT278495 IGFBP2 Positive_regulation of Gene_expression of IGF1 1 0.20 0 0
80 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0
81 INT128489 IGF1 Negative_regulation of Positive_regulation of INS 1 0.26 0.38 0
82 INT75319 IGF1 Positive_regulation of Gh 1 0.00 0.26 0
83 INT87748 IGF1 Positive_regulation of INS 1 0.41 0.17 0
84 INT264297 Binding of IGF1 and NOL3 1 0.36 0.44 0
85 INT218615 Negative_regulation of INS Negative_regulation of Gene_expression of IGF1 1 0.33 0.89 0
86 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0
87 INT137934 IGF1 Regulation of Tgfb1 1 0.00 0 0
88 INT202247 Binding of IGF1 and Igfbp1 1 0.16 0.21 0
89 INT16355 GH1 Positive_regulation of IGF1 1 0.24 0.25 0
90 INT213264 INS Positive_regulation of Localization of IGF1 1 0.16 1.77 0
91 INT246469 Binding of IGF1 and Gh 1 0.03 0.2 0
92 INT278494 IGFBP3 Positive_regulation of Binding of IGF1 and IGFBP3 1 0.17 0 0
93 INT137929 IGF1 Regulation of TGFB3 1 0.00 0 0
94 INT349955 ARMC9 Regulation of IGF1 1 0.01 0 0
95 INT75318 Gh Regulation of Gene_expression of IGF1 1 0.00 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3479. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3479. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
2 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
3 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
4 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
5 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
6 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
7 INT34777 Localization of IGF1 82 0.80 42.68 8.62
8 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
9 INT16130 Binding of IGF1 67 0.48 27.43 2.95
10 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
11 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
12 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
13 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
14 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
15 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
16 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
17 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53
18 INT49672 Regulation of Negative_regulation of IGF1 1 0.21 1.07 0.33
19 INT169405 Negative_regulation of Phosphorylation of IGF1 1 0.07 0.15 0.32
20 INT265899 Regulation of Binding of IGF1 2 0.22 0.94 0.22
21 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18
22 INT212553 Negative_regulation of Transcription of IGF1 1 0.39 0.3 0.12
23 INT48615 Positive_regulation of Binding of IGF1 5 0.50 0.54 0.11
24 INT318819 Positive_regulation of Transcription of IGF1 1 0.33 1.94 0.07
25 INT202238 Regulation of Transcription of IGF1 1 0.38 0 0.06
26 INT294924 Regulation of Localization of IGF1 3 0.39 1.07 0
27 INT202239 Negative_regulation of Negative_regulation of IGF1 2 0.39 0.53 0
28 INT274266 Regulation of Positive_regulation of IGF1 1 0.35 0.17 0
29 INT264308 Negative_regulation of Regulation of IGF1 1 0.39 0.23 0
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