G:3497

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Official Symbol IGHE
Aliases IgE
EntrezGene 3497
UniProt Coming Soon
Unique Molecular Interactions 53
Total Molecular Interactions 73
Total Single Events 1514
Unique Interaction Partners 34

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IGHE. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IGHE. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IGHE. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT353741 Binding of IGHE and Aia1 1 0.00 1.16 1.06
2 INT250016 Binding of IGHE and Il13 1 0.01 4.59 0.97
3 INT333499 Binding of IGHE and PHB2 1 0.14 4.08 0.95
4 INT211105 Binding of CRS and IGHE 1 0.02 3.63 0.66
5 INT62035 PDYN Regulation of Gene_expression of IGHE 1 0.33 0 0.57
6 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55
7 INT87555 TPSAB1 Positive_regulation of IGHE 1 0.42 0.71 0.43
8 INT304102 Il13 Positive_regulation of Gene_expression of IGHE 1 0.25 2.65 0.4
9 INT304099 Binding of IGHE and Il13 1 0.17 4.13 0.38
10 INT340850 Binding of IGHE and Baat 1 0.07 0.27 0.37
11 INT310934 Positive_regulation of Tgm2 Positive_regulation of Binding of IGHE 1 0.14 1.33 0.34
12 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
13 INT133391 Positive_regulation of Binding of IGHE and IgG 1 0.03 2.88 0.27
14 INT133393 Binding of IGHE and IgG 1 0.03 2.86 0.27
15 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27
16 INT62033 POMC Regulation of Gene_expression of IGHE 1 0.64 0 0.24
17 INT335462 IGHE Regulation of Positive_regulation of PRKCA 1 0.07 0 0.23
18 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22
19 INT226368 Positive_regulation of TNF Positive_regulation of Positive_regulation of IGHE 1 0.11 0.92 0.2
20 INT250003 Binding of IGHE and IL13 1 0.03 1.16 0.18
21 INT49058 Binding of IGHE and Positive_regulation of Localization of PTGDS 1 0.29 0.35 0.17
22 INT226359 IL21 Negative_regulation of Gene_expression of IGHE 1 0.02 0.79 0.16
23 INT51355 Binding of FCGR1A and IGHE 1 0.36 0.1 0.15
24 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13
25 INT202543 Binding of IGHE and IL10 1 0.03 0.79 0.12
26 INT270566 IGHE Regulation of IL4 1 0.21 0.99 0.09
27 INT304581 IL4 Positive_regulation of Gene_expression of IGHE 1 0.17 0.35 0.09
28 INT194385 Il13 Positive_regulation of Gene_expression of IGHE 1 0.00 0.8 0.09
29 INT270567 IGHE Regulation of IL13RA2 1 0.23 0.99 0.09
30 INT270569 IGHE Regulation of IL5 1 0.18 1.04 0.09
31 INT202541 IL4 Regulation of IGHE 1 0.02 0.49 0.08
32 INT202545 Binding of IGHE and IL4 1 0.03 0.49 0.08
33 INT230883 Binding of IGHE and tryptase 1 0.01 0.23 0.07
34 INT320161 Binding of IGHE and IGHG3 1 0.02 0.35 0.06
35 INT202542 IGHE Positive_regulation of Localization of IL4 1 0.06 0.44 0.05
36 INT347021 Cd86 Positive_regulation of Gene_expression of IGHE 1 0.03 0.18 0.05
37 INT202547 IGHE Positive_regulation of Localization of IL13 1 0.04 0.44 0.05
38 INT202546 Binding of FCER1A and IGHE 1 0.02 0.49 0.04
39 INT334497 Positive_regulation of IGHG3 Positive_regulation of IGHE 1 0.01 0.81 0.04
40 INT334496 IGHG3 Positive_regulation of IGHE 1 0.01 0.75 0.04
41 INT195195 IL4 Regulation of Gene_expression of IGHE 1 0.10 0.68 0.04
42 INT270586 Binding of IGHE and IgG-2a 1 0.16 0.75 0.03
43 INT199041 AGRP Regulation of IGHE 1 0.00 1.39 0.03
44 INT251864 Binding of HLA-DRB1 and IGHE 1 0.04 0.23 0
45 INT195199 Gene_expression of IL4 Positive_regulation of Gene_expression of IGHE 1 0.08 1.76 0
46 INT195198 Gene_expression of IL5 Positive_regulation of Gene_expression of IGHE 1 0.09 1.76 0
47 INT195197 Gene_expression of IL9 Positive_regulation of Gene_expression of IGHE 1 0.05 1.77 0
48 INT195196 IL13 Positive_regulation of Gene_expression of IGHE 1 0.06 1.79 0
49 INT306566 Binding of IGHE and GOPC 1 0.06 0.18 0
50 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0
51 INT195200 IL10 Positive_regulation of Gene_expression of IGHE 1 0.07 1.78 0
52 INT241260 Binding of IGHE and OPCML 1 0.02 1.08 0
53 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3497. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3497. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46
2 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16
3 INT8775 Binding of IGHE 167 0.48 102.61 23.54
4 INT701 Localization of IGHE 87 0.80 40.5 10.62
5 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74
6 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61
7 INT2971 Regulation of IGHE 42 0.61 28.81 7.87
8 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27
9 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53
10 INT24871 Negative_regulation of Binding of IGHE 10 0.58 2.87 2.64
11 INT35866 Transcription of IGHE 9 0.60 12.83 2.19
12 INT9996 Positive_regulation of Localization of IGHE 8 0.49 1.95 1.8
13 INT35865 Positive_regulation of Transcription of IGHE 3 0.44 2.61 1.03
14 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1
15 INT22004 Positive_regulation of Binding of IGHE 7 0.49 3.29 0.96
16 INT122197 Regulation of Localization of IGHE 3 0.42 0.92 0.95
17 INT334504 Regulation of Transcription of IGHE 1 0.29 7.97 0.57
18 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53
19 INT4642 Regulation of Regulation of IGHE 1 0.45 1.88 0.53
20 INT95906 Negative_regulation of Positive_regulation of IGHE 6 0.55 1.56 0.36
21 INT9997 Negative_regulation of Localization of IGHE 4 0.42 0.28 0.28
22 INT211181 Protein_catabolism of IGHE 1 0.07 1.28 0.25
23 INT57779 Positive_regulation of Regulation of IGHE 1 0.04 1.36 0.19
24 INT300748 Negative_regulation of Negative_regulation of IGHE 1 0.38 0.55 0
25 INT194241 Phosphorylation of IGHE 1 0.09 0.11 0
26 INT300747 Positive_regulation of Negative_regulation of IGHE 1 0.41 0.63 0
27 INT186772 Regulation of Binding of IGHE 1 0.05 0 0
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