G:3557

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Official Symbol IL1RN
Aliases DIRA, IRAP, IL1F3, IL1RA, MVCD4, IL-1RN, IL-1ra, IL-1ra3, ICIL-1RA, MGC10430
EntrezGene 3557
UniProt Coming Soon
Unique Molecular Interactions 34
Total Molecular Interactions 59
Total Single Events 509
Unique Interaction Partners 18

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IL1RN. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IL1RN. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IL1RN. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
2 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
3 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64
4 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
5 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
6 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88
7 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
8 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68
9 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
10 INT92872 SON Positive_regulation of IL1RN 1 0.06 0.64 0.65
11 INT279398 Binding of IL1RN and Il1rn 1 0.00 0.51 0.63
12 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61
13 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61
14 INT85487 IL1RN Negative_regulation of IL1R1 1 0.02 0 0.57
15 INT279392 SFTPA1 Positive_regulation of IL1RN 1 0.00 0.19 0.4
16 INT224584 Binding of IL1RN and SIGMAR1 1 0.00 0.73 0.36
17 INT334948 IL6 Positive_regulation of IL6 Regulation of IL1RN 1 0.17 1.11 0.35
18 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35
19 INT334947 IL6 Regulation of IL6 Positive_regulation of IL1RN 1 0.10 1.11 0.35
20 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35
21 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35
22 INT92871 Positive_regulation of SON Positive_regulation of IL1RN 1 0.06 0.33 0.34
23 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
24 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
25 INT220243 IL1RN Negative_regulation of Gene_expression of DPEP1 1 0.20 0.22 0.19
26 INT220240 IL1RN Negative_regulation of Gene_expression of MOCS1 1 0.01 0 0.12
27 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12
28 INT220248 IL1RN Regulation of Gene_expression of LONP1 1 0.04 0 0.08
29 INT220241 IL1RN Regulation of Gene_expression of DPEP1 1 0.24 0 0.08
30 INT220238 IL1RN Regulation of Protein_catabolism of DPEP1 1 0.14 0 0.08
31 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
32 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
33 INT220236 Positive_regulation of IL1RN Negative_regulation of Gene_expression of MOCS1 1 0.01 0 0.03
34 INT164244 Binding of IL1RN and Mmp3 1 0.01 0 0
35 INT164245 Negative_regulation of Binding of IL1RN and Mmp3 1 0.01 0 0
36 INT186415 IL1RN Regulation of Gene_expression of IL1B 1 0.25 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3557. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3557. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62
2 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66
3 INT72565 Localization of IL1RN 45 0.80 23.59 13.17
4 INT87844 Binding of IL1RN 40 0.41 24.37 11.92
5 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31
6 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99
7 INT73902 Regulation of Gene_expression of IL1RN 6 0.61 4.59 6.14
8 INT73905 Transcription of IL1RN 10 0.71 9.16 5.04
9 INT92199 Negative_regulation of Gene_expression of IL1RN 14 0.58 10.11 4.71
10 INT81485 Negative_regulation of IL1RN 19 0.57 8.3 4.69
11 INT73904 Positive_regulation of Localization of IL1RN 2 0.69 1.5 1.38
12 INT92873 Positive_regulation of Positive_regulation of IL1RN 3 0.47 1.82 1.28
13 INT165401 Phosphorylation of IL1RN 2 0.09 1.51 0.91
14 INT73903 Positive_regulation of Transcription of IL1RN 2 0.69 1.15 0.87
15 INT187381 Regulation of Localization of IL1RN 1 0.00 1.05 0.74
16 INT323910 Negative_regulation of Positive_regulation of IL1RN 1 0.05 0.57 0.42
17 INT220260 Protein_catabolism of IL1RN 1 0.59 0.14 0
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