G:3605

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Official Symbol IL17A
Aliases IL17, CTLA8, IL-17, IL-17A
EntrezGene 3605
UniProt Coming Soon
Unique Molecular Interactions 30
Total Molecular Interactions 40
Total Single Events 304
Unique Interaction Partners 21

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IL17A. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IL17A. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IL17A. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
2 INT346266 MTX1 Regulation of IL17A 1 0.08 1.33 0.89
3 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74
4 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
5 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53
6 INT349636 IL17A Positive_regulation of Gene_expression of IL4 1 0.06 1.28 0.5
7 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
8 INT293202 IK Regulation of Gene_expression of IL17A 1 0.00 0 0.48
9 INT172149 IL17A Positive_regulation of Gene_expression of IL1B 1 0.01 0.5 0.43
10 INT172138 IL17A Positive_regulation of Gene_expression of TNF 1 0.07 0.5 0.43
11 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39
12 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
13 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
14 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34
15 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
16 INT355984 PDC Positive_regulation of Gene_expression of IL17A 1 0.06 1.57 0.31
17 INT355979 Negative_regulation of PDC Positive_regulation of Gene_expression of IL17A 1 0.06 1.57 0.31
18 INT285945 IL17A Regulation of IL6 1 0.13 1.22 0.2
19 INT181617 IL17A Positive_regulation of ISYNA1 1 0.01 0.27 0.2
20 INT296036 IL6 Positive_regulation of IL17A 1 0.04 0.05 0.17
21 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
22 INT296079 IL17A Negative_regulation of Positive_regulation of Gtf3a 1 0.00 0.77 0.13
23 INT296040 IL17A Regulation of TH1L 1 0.07 0.7 0.12
24 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11
25 INT183798 IL17A Positive_regulation of IL17A Positive_regulation of MMP9 1 0.27 0.24 0.1
26 INT183797 IL17A Positive_regulation of Positive_regulation of MMP2 1 0.03 0.24 0.1
27 INT183796 IL17A Positive_regulation of MMP9 1 0.28 0.24 0.1
28 INT183795 IL17A Positive_regulation of Positive_regulation of MMP9 1 0.30 0.24 0.1
29 INT285947 IL6 Regulation of IL17A 1 0.08 0.44 0.05
30 INT285936 IL17A Positive_regulation of Gene_expression of POU5F1 1 0.10 0.34 0.04
31 INT285949 IL6 Positive_regulation of Gene_expression of IL17A 1 0.14 0.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3605. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3605. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33
2 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82
3 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15
4 INT173584 Localization of IL17A 14 0.74 10.83 5.19
5 INT155011 Negative_regulation of IL17A 8 0.54 6.43 3.64
6 INT183809 Regulation of IL17A 11 0.25 6.6 2.37
7 INT183808 Regulation of Gene_expression of IL17A 6 0.42 4.12 2.01
8 INT155012 Negative_regulation of Gene_expression of IL17A 11 0.36 8.64 1.94
9 INT250894 Positive_regulation of Localization of IL17A 5 0.46 2.49 1.19
10 INT203119 Positive_regulation of Positive_regulation of IL17A 2 0.46 1.12 0.76
11 INT183815 Binding of IL17A 5 0.34 1.33 0.4
12 INT183812 Negative_regulation of Positive_regulation of IL17A 1 0.36 0.08 0.31
13 INT183811 Transcription of IL17A 3 0.58 0.11 0.2
14 INT296062 Positive_regulation of Transcription of IL17A 1 0.15 0.11 0.2
15 INT329445 Negative_regulation of Localization of IL17A 1 0.39 0.6 0.13
16 INT285951 Negative_regulation of Binding of IL17A 1 0.18 0.1 0
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