G:361

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Official Symbol AQP4
Aliases MIWC, HMIWC2, MGC22454
EntrezGene 361
UniProt Coming Soon
Unique Molecular Interactions 22
Total Molecular Interactions 48
Total Single Events 317
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to AQP4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to AQP4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to AQP4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
2 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
3 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
4 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75
5 INT250247 FCGR3A Negative_regulation of AQP4 1 0.01 0.87 0.62
6 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55
7 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53
8 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
9 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
10 INT250242 Binding of AQP4 and GOPC 1 0.06 0.39 0.35
11 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32
12 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
13 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26
14 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
15 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
16 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
17 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14
18 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
19 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0
20 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0
21 INT308703 Positive_regulation of Binding of AQP4 and M1 1 0.08 0.61 0
22 INT308707 Binding of AQP4 and IGHG3 1 0.01 0.88 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 361. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 361. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53
2 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07
3 INT157959 Binding of AQP4 32 0.48 43.44 7.44
4 INT157960 Regulation of AQP4 11 0.48 21.36 3.06
5 INT169747 Localization of AQP4 17 0.75 16.64 2.79
6 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47
7 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85
8 INT251679 Negative_regulation of Gene_expression of AQP4 2 0.38 10.37 0.77
9 INT327779 Regulation of Gene_expression of AQP4 5 0.48 4.5 0.6
10 INT327785 Transcription of AQP4 3 0.56 2.19 0.23
11 INT250270 Regulation of Localization of AQP4 1 0.41 0.22 0.2
12 INT327780 Negative_regulation of Negative_regulation of AQP4 1 0.33 1.12 0.18
13 INT250280 Positive_regulation of Negative_regulation of AQP4 1 0.37 0.58 0.17
14 INT250279 Positive_regulation of Localization of AQP4 1 0.46 0.69 0.13
15 INT327778 Positive_regulation of Regulation of AQP4 1 0.37 2.84 0.07
16 INT327783 Regulation of Transcription of AQP4 1 0.35 1.03 0
17 INT327788 Regulation of Regulation of AQP4 1 0.21 0.75 0
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