G:3645

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Official Symbol INSRR
Aliases IRR
EntrezGene 3645
UniProt Coming Soon
Unique Molecular Interactions 51
Total Molecular Interactions 79
Total Single Events 325
Unique Interaction Partners 34

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to INSRR. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to INSRR. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to INSRR. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
2 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46
3 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27
4 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
5 INT341534 INSRR Positive_regulation of F2RL1 1 0.00 1.4 0.7
6 INT144459 Binding of GPM6A and INSRR 1 0.00 0 0.67
7 INT94020 Binding of EDN2 and INSRR 1 0.03 0 0.65
8 INT81792 AGRP Negative_regulation of INSRR 3 0.01 0 0.55
9 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
10 INT89649 INSRR Regulation of ADCY1 1 0.00 0.07 0.44
11 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4
12 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4
13 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
14 INT71518 Binding of INSRR and Nisch 1 0.00 0.22 0.35
15 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34
16 INT136007 Binding of INSRR and KNG1 1 0.00 0.17 0.34
17 INT84426 Binding of TSPO and INSRR 1 0.01 0.22 0.3
18 INT70184 INSRR Positive_regulation of FOS 1 0.03 0.09 0.29
19 INT70186 PRCP Positive_regulation of INSRR 1 0.01 0.09 0.29
20 INT189692 INSRR Positive_regulation of PRKCA 1 0.00 0 0.24
21 INT192331 UBR7 Negative_regulation of INSRR 1 0.00 0.54 0.23
22 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
23 INT94017 Binding of EDN3 and INSRR 1 0.03 0 0.16
24 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
25 INT224308 INSRR Regulation of VEGFA 1 0.00 1.42 0.16
26 INT94013 Positive_regulation of Binding of EDN2 and INSRR 1 0.04 0 0.16
27 INT94019 Positive_regulation of Binding of EDN3 and INSRR 1 0.04 0 0.16
28 INT58403 INSRR Negative_regulation of RTCA 1 0.00 0.06 0.15
29 INT189694 Negative_regulation of INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15
30 INT189695 INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15
31 INT189647 INSRR Negative_regulation of CHKB Regulation of Negative_regulation of PRKCA 1 0.00 0.07 0.15
32 INT153028 Binding of INSRR and KCNMA1 1 0.06 0.29 0.1
33 INT153026 Binding of HTR3A and INSRR 1 0.13 0.29 0.1
34 INT143399 Binding of INSRR and NMU 1 0.01 0.12 0.09
35 INT119859 Gabbr1 Positive_regulation of INSRR 1 0.00 0 0.09
36 INT251775 AGK Negative_regulation of INSRR 1 0.00 1.1 0.07
37 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
38 INT71160 Positive_regulation of INSRR Positive_regulation of Binding of ANGPTL5 1 0.00 0.25 0
39 INT189648 CCND3 Regulation of CHKB Regulation of INSRR 1 0.00 0.06 0
40 INT189678 Positive_regulation of CHKB Regulation of INSRR 1 0.00 0.06 0
41 INT189686 CHKB Regulation of Negative_regulation of INSRR 1 0.00 0.46 0
42 INT189705 INSRR Negative_regulation of Gene_expression of TERT 1 0.00 0.46 0
43 INT71159 Binding of INSRR and ANGPTL5 1 0.00 0.25 0
44 INT189697 INSRR Regulation of Gene_expression of TERT 1 0.00 0.46 0
45 INT202431 Binding of IGF2 and INSRR 1 0.01 0.85 0
46 INT189683 CHKB Negative_regulation of Negative_regulation of INSRR 1 0.00 0.46 0
47 INT189669 INSRR Regulation of TERT 1 0.00 0 0
48 INT102798 OPRM1 Regulation of INSRR 1 0.01 0 0
49 INT189672 Positive_regulation of INSRR Regulation of Transcription of TERT 1 0.00 0.23 0
50 INT189667 INSRR Regulation of CHKB 1 0.00 0.06 0
51 INT189706 CHKB Regulation of INSRR 1 0.00 0.06 0
52 INT114711 SRC Positive_regulation of Gene_expression of INSRR 1 0.01 0.51 0
53 INT189691 CHKB Negative_regulation of Positive_regulation of INSRR 1 0.00 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3645. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3645. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9781 Binding of INSRR 64 0.31 19.1 25.2
2 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52
3 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38
4 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85
5 INT12632 Negative_regulation of Binding of INSRR 13 0.38 6.54 6.39
6 INT12631 Positive_regulation of Binding of INSRR 11 0.45 6.13 6.04
7 INT12474 Regulation of INSRR 18 0.29 6.29 4.81
8 INT51178 Transcription of INSRR 9 0.17 2.09 3.09
9 INT33241 Localization of INSRR 10 0.10 1.24 3.08
10 INT51149 Positive_regulation of Gene_expression of INSRR 5 0.17 2.94 1.86
11 INT88518 Negative_regulation of Positive_regulation of INSRR 4 0.27 2.26 1.86
12 INT89652 Phosphorylation of INSRR 4 0.01 1.36 1.6
13 INT72590 Regulation of Binding of INSRR 1 0.15 1.79 1.02
14 INT163543 Positive_regulation of Localization of INSRR 1 0.03 0 0.68
15 INT89654 Positive_regulation of Negative_regulation of INSRR 2 0.01 0.37 0.49
16 INT192345 Positive_regulation of Phosphorylation of INSRR 1 0.01 0.68 0.27
17 INT250992 Regulation of Gene_expression of INSRR 2 0.00 1.22 0.24
18 INT95659 Negative_regulation of Gene_expression of INSRR 1 0.02 0.51 0.13
19 INT189730 Negative_regulation of Negative_regulation of INSRR 3 0.01 0.09 0.03
20 INT261550 Regulation of Positive_regulation of INSRR 1 0.00 0 0.03
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