G:3667

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Official Symbol IRS1
Aliases HIRS-1
EntrezGene 3667
UniProt Coming Soon
Unique Molecular Interactions 13
Total Molecular Interactions 15
Total Single Events 138
Unique Interaction Partners 9

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IRS1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IRS1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IRS1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
2 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
3 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
4 INT267158 Binding of IRS1 and SHMT2 1 0.02 0.46 0.05
5 INT321407 EDN1 Positive_regulation of Phosphorylation of IRS1 1 0.06 1.07 0.03
6 INT207555 GH1 Negative_regulation of Phosphorylation of IRS1 1 0.10 0.28 0.03
7 INT332284 IRS1 Regulation of PIK3CD 1 0.15 0.72 0.03
8 INT332288 Positive_regulation of IRS1 Regulation of PIK3CD 1 0.07 0.73 0.03
9 INT284311 RPS6KB1 Positive_regulation of Phosphorylation of IRS1 1 0.18 0.24 0
10 INT304350 INS Positive_regulation of Protein_catabolism of IRS1 1 0.09 0.78 0
11 INT304347 INS Positive_regulation of Phosphorylation of IRS1 1 0.09 0.77 0
12 INT284313 Binding of IRS1 and SART3 1 0.07 0.32 0
13 INT284312 Negative_regulation of Binding of IRS1 and SART3 1 0.08 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3667. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3667. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT207570 Phosphorylation of IRS1 45 0.71 33.27 3.42
2 INT240031 Positive_regulation of Phosphorylation of IRS1 15 0.46 13.17 1.53
3 INT89407 Positive_regulation of IRS1 10 0.51 9.67 0.81
4 INT321433 Negative_regulation of IRS1 3 0.32 5.41 0.75
5 INT284334 Gene_expression of IRS1 10 0.49 5.81 0.59
6 INT321417 Positive_regulation of Negative_regulation of IRS1 1 0.12 3.82 0.51
7 INT235635 Negative_regulation of Phosphorylation of IRS1 7 0.37 3.78 0.42
8 INT89406 Negative_regulation of Positive_regulation of IRS1 1 0.22 0.93 0.22
9 INT284323 Regulation of IRS1 2 0.45 1.6 0.16
10 INT304385 Protein_catabolism of IRS1 2 0.42 1.8 0.1
11 INT332299 Negative_regulation of Gene_expression of IRS1 1 0.31 0.65 0.04
12 INT235632 Binding of IRS1 2 0.28 1.01 0.03
13 INT284335 Regulation of Gene_expression of IRS1 1 0.18 0.06 0.03
14 INT304382 Positive_regulation of Protein_catabolism of IRS1 1 0.16 0.77 0
15 INT284324 Positive_regulation of Gene_expression of IRS1 1 0.31 0.24 0
16 INT304383 Negative_regulation of Protein_catabolism of IRS1 1 0.15 0.77 0
17 INT235630 Localization of IRS1 1 0.70 0.38 0
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