G:3683

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Official Symbol ITGAL
Aliases CD11A, LFA-1, LFA1A
EntrezGene 3683
UniProt Coming Soon
Unique Molecular Interactions 32
Total Molecular Interactions 61
Total Single Events 137
Unique Interaction Partners 20

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ITGAL. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ITGAL. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ITGAL. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
2 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
3 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
4 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
5 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
6 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
7 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78
8 INT81717 ITGAL Regulation of Gene_expression of ITGAM 1 0.30 0.17 0.78
9 INT81718 ITGAL Regulation of Gene_expression of FCGR3B 1 0.28 0.17 0.78
10 INT81711 ITGAL Regulation of Gene_expression of ITGB2 1 0.30 0.17 0.78
11 INT81713 ITGAL Regulation of ITGAM 1 0.30 0.17 0.77
12 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75
13 INT265651 Binding of ITGAL and MYCN 1 0.00 0.46 0.62
14 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
15 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51
16 INT102691 RETNLB Positive_regulation of ITGAL 1 0.01 0.45 0.45
17 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28
18 INT173406 Binding of ITGAL and Itgb2 1 0.02 0.41 0.13
19 INT232652 Binding of CD2 and ITGAL 1 0.03 0.28 0.09
20 INT279400 GANAB Regulation of ITGAL 1 0.01 0.75 0.09
21 INT173371 GPER Regulation of ITGAL 1 0.01 0.23 0.08
22 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07
23 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 0.06 0.2 0.07
24 INT284504 ITGAL Positive_regulation of Gene_expression of ITGAM 1 0.03 0.2 0.06
25 INT260811 Binding of ITGA4 and ITGAL 1 0.02 0 0.03
26 INT170121 ITGAL Regulation of CD44 1 0.07 1.07 0
27 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0
28 INT79649 RIMS3 Regulation of Positive_regulation of ITGAL 1 0.00 0 0
29 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
30 INT301095 Binding of ITGAL and CHDH 1 0.00 0.71 0
31 INT170114 ITGAM Regulation of Positive_regulation of ITGAL 1 0.04 1.07 0
32 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3683. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3683. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61417 Gene_expression of ITGAL 36 0.75 29.62 6.15
2 INT87322 Binding of ITGAL 23 0.47 15.73 4.68
3 INT61418 Positive_regulation of ITGAL 24 0.14 12.86 2.3
4 INT12942 Regulation of ITGAL 8 0.35 3.29 1.57
5 INT81723 Regulation of Gene_expression of ITGAL 2 0.32 0.2 0.92
6 INT115964 Negative_regulation of ITGAL 7 0.34 3.76 0.86
7 INT186135 Negative_regulation of Binding of ITGAL 5 0.34 3.27 0.74
8 INT102695 Localization of ITGAL 2 0.73 1.26 0.61
9 INT63357 Negative_regulation of Gene_expression of ITGAL 3 0.33 1.88 0.56
10 INT133729 Positive_regulation of Gene_expression of ITGAL 8 0.49 2.96 0.48
11 INT114900 Negative_regulation of Positive_regulation of ITGAL 1 0.01 1.32 0.29
12 INT12940 Positive_regulation of Transcription of ITGAL 1 0.02 0.09 0.26
13 INT12941 Transcription of ITGAL 1 0.03 0.09 0.26
14 INT61416 Positive_regulation of Positive_regulation of ITGAL 4 0.11 0.85 0.23
15 INT83483 Regulation of Regulation of ITGAL 2 0.01 0.3 0.04
16 INT83476 Positive_regulation of Regulation of ITGAL 1 0.00 0 0
17 INT79661 Phosphorylation of ITGAL 1 0.01 0 0
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