G:3717

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Official Symbol JAK2
Aliases JTK10, THCYT3
EntrezGene 3717
UniProt Coming Soon
Unique Molecular Interactions 17
Total Molecular Interactions 18
Total Single Events 79
Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to JAK2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to JAK2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to JAK2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
2 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
3 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
4 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
5 INT118842 Negative_regulation of JAK2 Negative_regulation of GNA14 Positive_regulation of STAT3 1 0.00 0.08 0.28
6 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
7 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
8 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
9 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06
10 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
11 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
12 INT238116 STAT3 Positive_regulation of Gene_expression of JAK2 1 0.16 0 0.05
13 INT300081 Binding of JAK2 and TYK2 1 0.09 1.13 0
14 INT350503 Binding of HSP90AA1 and JAK2 1 0.06 1.39 0
15 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0
16 INT198026 JAK2 Positive_regulation of HCC 1 0.19 1.35 0
17 INT350505 Negative_regulation of Binding of HSP90AA1 and JAK2 1 0.07 1.5 0
18 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3717. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3717. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113339 Binding of JAK2 6 0.40 5.31 2.4
2 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
3 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
4 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
5 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
6 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
7 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
8 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
9 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
10 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
11 INT238200 Localization of JAK2 1 0.16 0 0.05
12 INT238199 Positive_regulation of Positive_regulation of JAK2 1 0.10 0 0.03
13 INT238196 Negative_regulation of Binding of JAK2 1 0.09 0 0
14 INT350506 Protein_catabolism of JAK2 1 0.48 1.55 0
15 INT320539 Negative_regulation of Phosphorylation of JAK2 1 0.26 0.46 0
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