G:3725

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Official Symbol JUN
Aliases AP1, AP-1, c-Jun
EntrezGene 3725
UniProt Coming Soon
Unique Molecular Interactions 77
Total Molecular Interactions 100
Total Single Events 518
Unique Interaction Partners 58

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to JUN. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to JUN. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to JUN. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
2 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
3 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
4 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
5 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
6 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
7 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
8 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
9 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
10 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
11 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
12 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
13 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
14 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
15 INT190145 Binding of JUN and MMP12 Positive_regulation of Positive_regulation of PIK3CA 1 0.01 0.57 0.57
16 INT190146 Positive_regulation of PIK3CA Positive_regulation of Binding of JUN and MMP12 1 0.01 0.57 0.57
17 INT190148 Binding of JUN and MMP12 Positive_regulation of MMP12 1 0.33 0.57 0.57
18 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
19 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
20 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
21 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
22 INT103132 Positive_regulation of DCSTAMP Positive_regulation of JUN 1 0.03 0.73 0.43
23 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43
24 INT103129 DCSTAMP Positive_regulation of JUN 1 0.03 0.72 0.43
25 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
26 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
27 INT97404 Nfkb1 Positive_regulation of Transcription of JUN 1 0.00 1.03 0.38
28 INT97403 JUN Positive_regulation of Transcription of Nfkb1 1 0.00 1.03 0.38
29 INT69391 Binding of JUN and MBTPS1 1 0.09 0.16 0.29
30 INT162040 F2 Positive_regulation of Localization of JUN 1 0.20 0.9 0.28
31 INT312042 GLC1N Negative_regulation of Positive_regulation of JUN 1 0.01 0.6 0.26
32 INT60195 Binding of CCK and JUN 1 0.39 0.09 0.25
33 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22
34 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2
35 INT114045 Binding of CREM and JUN 1 0.03 0.17 0.19
36 INT114044 Positive_regulation of Binding of CREM and JUN 1 0.04 0.17 0.19
37 INT240435 JUN Positive_regulation of Gene_expression of CPOX 1 0.01 0.81 0.18
38 INT107884 Stat3 Positive_regulation of JUN 1 0.08 0 0.17
39 INT69383 Positive_regulation of Binding of JUN and MBTPS1 1 0.09 0.16 0.16
40 INT275374 JUN Positive_regulation of NDRG1 1 0.00 1.35 0.15
41 INT329168 MAPK8 Positive_regulation of Localization of JUN 1 0.12 0.56 0.15
42 INT329172 Phosphorylation of MAPK8 Positive_regulation of Localization of JUN 1 0.12 0.62 0.15
43 INT306272 CRKL Positive_regulation of JUN 1 0.05 0.54 0.14
44 INT69377 CNTN2 Positive_regulation of Binding of JUN 1 0.49 0 0.14
45 INT69384 MBTPS1 Positive_regulation of Binding of JUN 1 0.09 0 0.14
46 INT275462 Negative_regulation of JUN Positive_regulation of Gene_expression of MMP9 1 0.04 0.27 0.12
47 INT173125 PPA1 Positive_regulation of JUN 1 0.06 0.5 0.12
48 INT107883 Stat3 Positive_regulation of Gene_expression of JUN 1 0.08 0 0.1
49 INT107878 Gene_expression of JUN Positive_regulation of Gene_expression of TRPC6 1 0.20 0 0.09
50 INT145153 JUN Positive_regulation of EGFR 1 0.24 0.94 0.09
51 INT77649 Positive_regulation of JUN Positive_regulation of Transcription of IL8 1 0.01 0.79 0.09
52 INT145154 Positive_regulation of JUN Positive_regulation of EGFR 1 0.24 0.95 0.09
53 INT306266 Binding of JUN and NFAT5 1 0.10 0.22 0.08
54 INT191755 ROS1 Positive_regulation of JUN 1 0.00 0.54 0.08
55 INT220916 Positive_regulation of Binding of JUN and JUND 2 0.18 0.53 0.07
56 INT220911 Binding of JUN and JUND 2 0.14 1.08 0.07
57 INT107877 JUN Positive_regulation of Gene_expression of TRPC6 1 0.13 0 0.07
58 INT152891 Ptger2 Positive_regulation of Positive_regulation of JUN 1 0.00 0.23 0.07
59 INT333568 FYN Regulation of Transcription of JUN 1 0.01 0 0.03
60 INT333564 CREB1 Regulation of Transcription of JUN 1 0.02 0 0.03
61 INT220912 GNS Negative_regulation of Phosphorylation of JUN 1 0.00 0 0
62 INT264380 Binding of JUN and MMP13 1 0.05 0 0
63 INT145150 Positive_regulation of Binding of EGFR and JUN 1 0.24 0.11 0
64 INT348533 Positive_regulation of Binding of FOSL2 and JUN 1 0.09 0.32 0
65 INT292146 JUN Regulation of FOSB 1 0.10 0.23 0
66 INT333570 CD14 Positive_regulation of JUN 1 0.04 0.09 0
67 INT338896 Binding of JUN and Jun 1 0.01 0.06 0
68 INT164905 IL1B Positive_regulation of JUN 1 0.13 0.07 0
69 INT145149 Binding of EGFR and JUN 1 0.16 0.11 0
70 INT333566 IRF6 Positive_regulation of JUN 1 0.01 0.09 0
71 INT198018 MAPK1 Positive_regulation of JUN 1 0.05 1.05 0
72 INT264386 Binding of JUN and MMP1 1 0.03 0 0
73 INT264394 Binding of DR1 and JUN 1 0.01 0.07 0
74 INT97565 JUN Positive_regulation of Gene_expression of ABCB1 1 0.45 0.06 0
75 INT348524 Binding of FOSL2 and JUN 1 0.07 0.59 0
76 INT164898 TNF Positive_regulation of JUN 1 0.06 0.07 0
77 INT348527 Binding of JUN and Regulation of Gene_expression of GADD45A 1 0.11 0.24 0
78 INT199977 ESR1 Positive_regulation of JUN 1 0.03 0.18 0
79 INT122540 FGF2 Positive_regulation of Binding of JUN 1 0.24 0 0
80 INT122543 FGF2 Positive_regulation of JUN 1 0.36 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3725. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3725. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
2 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
3 INT60198 Binding of JUN 54 0.48 11.56 10.27
4 INT75497 Regulation of JUN 28 0.61 11.04 7.09
5 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
6 INT67936 Transcription of JUN 18 0.52 9.52 4.13
7 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
8 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
9 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
10 INT123682 Localization of JUN 8 0.50 4.15 2.38
11 INT60199 Positive_regulation of Binding of JUN 5 0.49 1.3 2.34
12 INT110925 Positive_regulation of Positive_regulation of JUN 14 0.49 6.22 1.98
13 INT130208 Positive_regulation of Phosphorylation of JUN 4 0.38 3.07 1.92
14 INT171029 Positive_regulation of Transcription of JUN 4 0.14 2.87 1.48
15 INT68652 Regulation of Positive_regulation of JUN 4 0.54 4.95 1.26
16 INT120764 Negative_regulation of Binding of JUN 7 0.25 2.65 1.23
17 INT75503 Regulation of Gene_expression of JUN 6 0.21 2.87 1.11
18 INT303710 Negative_regulation of Transcription of JUN 1 0.06 0.84 0.65
19 INT123681 Positive_regulation of Localization of JUN 2 0.25 1.3 0.59
20 INT113840 Negative_regulation of Gene_expression of JUN 10 0.58 5.23 0.56
21 INT74209 Positive_regulation of Negative_regulation of JUN 1 0.45 0.26 0.47
22 INT139522 Positive_regulation of Regulation of JUN 1 0.49 0.37 0.41
23 INT209939 Negative_regulation of Localization of JUN 1 0.23 0.35 0.2
24 INT110182 Negative_regulation of Phosphorylation of JUN 1 0.41 0.81 0.19
25 INT264428 Regulation of Transcription of JUN 3 0.10 0 0.03
26 INT144821 Negative_regulation of Negative_regulation of JUN 1 0.51 0 0
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