G:384783

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Official Symbol Irs2
Aliases Irs-2
EntrezGene 384783
UniProt Coming Soon
Unique Molecular Interactions 11
Total Molecular Interactions 11
Total Single Events 69
Unique Interaction Partners 9

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Irs2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Irs2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Irs2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT301641 Irs2 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08
2 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 0.04 0.65 0.08
3 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 0.08 0.62 0.08
4 INT184101 Binding of Irs2 and Sh2 1 0.05 0.15 0.03
5 INT184136 Binding of Socs7 and Irs2 1 0.13 0.15 0.03
6 INT184131 Binding of Socs6 and Irs2 1 0.11 0.2 0.03
7 INT323120 Negative_regulation of Irs2 Positive_regulation of Positive_regulation of Akt1 1 0.37 0 0
8 INT321720 Binding of Ppp1r13b and Irs2 1 0.11 0.13 0
9 INT240892 Negative_regulation of Ros1 Negative_regulation of Phosphorylation of Irs2 1 0.11 0.17 0
10 INT240884 Negative_regulation of Ros1 Negative_regulation of Gene_expression of Irs2 1 0.15 0.12 0
11 INT323121 Negative_regulation of Irs2 Negative_regulation of Positive_regulation of Akt1 1 0.34 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 384783. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 384783. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT240825 Gene_expression of Irs2 14 0.78 3.88 0.32
2 INT240819 Phosphorylation of Irs2 10 0.71 4.75 0.25
3 INT250513 Negative_regulation of Irs2 8 0.56 4.04 0.23
4 INT301519 Positive_regulation of Negative_regulation of Irs2 2 0.50 0.93 0.09
5 INT349622 Negative_regulation of Negative_regulation of Irs2 1 0.41 1.98 0.09
6 INT301523 Positive_regulation of Gene_expression of Irs2 1 0.09 0.68 0.08
7 INT240855 Negative_regulation of Phosphorylation of Irs2 4 0.34 2.18 0.07
8 INT301577 Binding of Irs2 2 0.26 0.62 0.07
9 INT184067 Protein_catabolism of Irs2 1 0.26 0.4 0.04
10 INT240853 Regulation of Irs2 2 0.45 1.1 0.03
11 INT323104 Positive_regulation of Irs2 1 0.50 1.37 0
12 INT323106 Negative_regulation of Gene_expression of Irs2 1 0.37 0 0
13 INT323101 Transcription of Irs2 1 0.60 0.52 0
14 INT240829 Localization of Irs2 1 0.51 0.05 0
15 INT240851 Regulation of Gene_expression of Irs2 1 0.35 0.12 0
16 INT323098 Positive_regulation of Transcription of Irs2 1 0.44 0 0
17 INT321699 Negative_regulation of Binding of Irs2 1 0.30 0 0
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