G:3949

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Official Symbol LDLR
Aliases FH, FHC, LDLCQ2
EntrezGene 3949
UniProt Coming Soon
Unique Molecular Interactions 26
Total Molecular Interactions 36
Total Single Events 310
Unique Interaction Partners 21

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to LDLR. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to LDLR. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to LDLR. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
2 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
3 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
4 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
5 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
6 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
7 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05
8 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04
9 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04
10 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
11 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04
12 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
13 INT251961 Binding of LDLR and SNRNP70 2 0.04 0.55 0
14 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
15 INT209987 Binding of APOE and LDLR 1 0.24 0 0
16 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0
17 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0
18 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
19 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0
20 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
21 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0
22 INT277045 APOB Positive_regulation of Binding of APOB and LDLR 1 0.38 0.82 0
23 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0
24 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0
25 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0
26 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
27 INT251964 Binding of LDLR and RS1 1 0.00 0.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3949. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3949. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
2 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
3 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
4 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
5 INT23199 Binding of LDLR 22 0.47 17.08 1.16
6 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
7 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
8 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
9 INT197012 Regulation of Gene_expression of LDLR 4 0.40 1.31 0.4
10 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24
11 INT17474 Negative_regulation of Positive_regulation of LDLR 4 0.37 2.93 0.16
12 INT209992 Negative_regulation of Transcription of LDLR 2 0.29 0 0.16
13 INT87515 Negative_regulation of Gene_expression of LDLR 2 0.09 1.96 0.16
14 INT197014 Localization of LDLR 8 0.63 3.29 0.03
15 INT176889 Negative_regulation of Binding of LDLR 2 0.41 1.2 0
16 INT276260 Negative_regulation of Localization of LDLR 2 0.40 1.34 0
17 INT39405 Regulation of Binding of LDLR 1 0.17 0 0
18 INT170750 Negative_regulation of Negative_regulation of LDLR 1 0.07 0.93 0
19 INT268450 Protein_catabolism of LDLR 1 0.07 0.14 0
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