G:4193

From wiki-pain
Jump to: navigation, search
Official Symbol MDM2
Aliases HDMX, hdm2, ACTFS, MGC5370, MGC71221
EntrezGene 4193
UniProt Coming Soon
Unique Molecular Interactions 18
Total Molecular Interactions 20
Total Single Events 82
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to MDM2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to MDM2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to MDM2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
2 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
3 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
4 INT193790 ITIH4 Regulation of Gene_expression of MDM2 1 0.06 0.45 0.07
5 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
6 INT314746 Akt1 Positive_regulation of Phosphorylation of MDM2 1 0.32 1.16 0
7 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
8 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
9 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
10 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
11 INT333450 ATM Positive_regulation of Negative_regulation of MDM2 1 0.18 0 0
12 INT208152 Binding of CDK4 and MDM2 1 0.01 1.11 0
13 INT294523 Binding of MDM2 and PDB1 1 0.40 0.1 0
14 INT333458 ATM Positive_regulation of MDM2 1 0.25 0 0
15 INT294527 Binding of MDM2 and p53 1 0.40 0.1 0
16 INT294524 Binding of MDM2 and TNF 1 0.03 0.1 0
17 INT294522 Binding of IL2 and MDM2 1 0.40 0.2 0
18 INT214922 Binding of MDM2 and TP53 1 0.08 1.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4193. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4193. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
2 INT167250 Regulation of Gene_expression of MDM2 1 0.06 0.86 0.21
3 INT88744 Positive_regulation of Gene_expression of MDM2 9 0.43 7.82 0.2
4 INT126733 Regulation of MDM2 2 0.36 0.73 0.16
5 INT113346 Binding of MDM2 10 0.35 5.73 0.15
6 INT287282 Regulation of Binding of MDM2 1 0.04 0.63 0.04
7 INT126734 Positive_regulation of MDM2 8 0.49 5.56 0
8 INT260276 Negative_regulation of MDM2 2 0.42 0.62 0
9 INT276357 Protein_catabolism of MDM2 2 0.32 1.18 0
10 INT276370 Phosphorylation of MDM2 2 0.50 1.99 0
11 INT294536 Localization of MDM2 1 0.73 0.09 0
12 INT121497 Transcription of MDM2 1 0.54 0.12 0
13 INT235473 Negative_regulation of Gene_expression of MDM2 1 0.18 0.99 0
14 INT276343 Regulation of Phosphorylation of MDM2 1 0.14 0.85 0
15 INT276359 Positive_regulation of Protein_catabolism of MDM2 1 0.15 1.79 0
16 INT276366 Positive_regulation of Phosphorylation of MDM2 1 0.15 0.85 0
17 INT113347 Negative_regulation of Binding of MDM2 1 0.25 0.13 0
18 INT276365 Negative_regulation of Protein_catabolism of MDM2 1 0.14 0.86 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox